pifithrin has been researched along with Myocardial Ischemia in 2 studies
pifithrin: a tetrahydrobenzothiazol; inhibitor of P53 that protects mice from the side effects of cancer therapy; structure in first source
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mocanu, MM | 1 |
| Yellon, DM | 1 |
| Liu, P | 1 |
| Xu, B | 1 |
| Cavalieri, TA | 1 |
| Hock, CE | 1 |
2 other studies available for pifithrin and Myocardial Ischemia
| Article | Year |
|---|---|
p53 down-regulation: a new molecular mechanism involved in ischaemic preconditioning.
Topics: Androstadienes; Animals; Benzothiazoles; Blotting, Northern; Down-Regulation; Enzyme Inhibitors; Isc | 2003 |
Pifithrin-alpha attenuates p53-mediated apoptosis and improves cardiac function in response to myocardial ischemia/reperfusion in aged rats.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Benzothiazoles; DNA Fragmentation; Electrocardiograp | 2006 |