pifithrin has been researched along with Myelodysplastic Syndromes in 2 studies
pifithrin: a tetrahydrobenzothiazol; inhibitor of P53 that protects mice from the side effects of cancer therapy; structure in first source
Myelodysplastic Syndromes: Clonal hematopoietic stem cell disorders characterized by dysplasia in one or more hematopoietic cell lineages. They predominantly affect patients over 60, are considered preleukemic conditions, and have high probability of transformation into ACUTE MYELOID LEUKEMIA.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dutt, S | 1 |
| Narla, A | 1 |
| Lin, K | 1 |
| Mullally, A | 1 |
| Abayasekara, N | 1 |
| Megerdichian, C | 1 |
| Wilson, FH | 1 |
| Currie, T | 1 |
| Khanna-Gupta, A | 1 |
| Berliner, N | 1 |
| Kutok, JL | 1 |
| Ebert, BL | 1 |
| Xu, H | 1 |
| Menendez, S | 1 |
| Schlegelberger, B | 1 |
| Bae, N | 1 |
| Aplan, PD | 1 |
| Göhring, G | 1 |
| Deblasio, TR | 1 |
| Nimer, SD | 1 |
2 other studies available for pifithrin and Myelodysplastic Syndromes
| Article | Year |
|---|---|
Haploinsufficiency for ribosomal protein genes causes selective activation of p53 in human erythroid progenitor cells.
Topics: Anemia, Diamond-Blackfan; Anemia, Macrocytic; Animals; Benzothiazoles; Cell Cycle; Cell Lineage; Cel | 2011 |
Loss of p53 accelerates the complications of myelodysplastic syndrome in a NUP98-HOXD13-driven mouse model.
Topics: Animals; Benzothiazoles; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Flow Cytom | 2012 |