pifithrin has been researched along with Liver Neoplasms in 6 studies
pifithrin: a tetrahydrobenzothiazol; inhibitor of P53 that protects mice from the side effects of cancer therapy; structure in first source
Liver Neoplasms: Tumors or cancer of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Human hepatoma cells (HepG2." | 1.38 | XPD could suppress growth of HepG2.2.15 and down-regulate the expression of hepatitis B virus x protein through P53 pathway. ( Ding, H; Du, FT; Huang, Y; Xu, JJ; Zhang, JX, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, W | 1 |
| Zhao, Z | 1 |
| Ni, Z | 1 |
| Zhao, Y | 1 |
| Du, W | 1 |
| Chen, S | 1 |
| Zhang, B | 1 |
| Yin, X | 1 |
| Sui, S | 1 |
| Guo, XL | 1 |
| Hu, F | 1 |
| Zhang, SS | 1 |
| Zhao, QD | 1 |
| Zong, C | 1 |
| Ye, F | 1 |
| Guo, SW | 1 |
| Zhang, JW | 1 |
| Li, R | 1 |
| Wu, MC | 1 |
| Wei, LX | 1 |
| Ding, H | 1 |
| Xu, JJ | 1 |
| Huang, Y | 1 |
| Du, FT | 1 |
| Zhang, JX | 1 |
| Farah, IO | 1 |
| Begum, RA | 1 |
| Ishaque, AB | 1 |
| Carlisi, D | 1 |
| Vassallo, B | 1 |
| Lauricella, M | 1 |
| Emanuele, S | 1 |
| D'Anneo, A | 1 |
| Di Leonardo, E | 1 |
| Di Fazio, P | 1 |
| Vento, R | 1 |
| Tesoriere, G | 1 |
6 other studies available for pifithrin and Liver Neoplasms
| Article | Year |
|---|---|
IFI16 restoration in hepatocellular carcinoma induces tumour inhibition via activation of p53 signals and inflammasome.
Topics: Benzothiazoles; Carcinoma, Hepatocellular; Cell Line; Humans; Inflammasomes; Liver Neoplasms; Nuclea | 2017 |
Resveratrol inhibited the progression of human hepatocellular carcinoma by inducing autophagy via regulating p53 and the phosphoinositide 3‑kinase/protein kinase B pathway.
Topics: Adenine; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Benzothiazoles; Carcinoma, Hepatoc | 2018 |
Inhibition of p53 increases chemosensitivity to 5-FU in nutrient-deprived hepatocarcinoma cells by suppressing autophagy.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Autophagy; Benzothiazoles; Carcinoma, Hepatocellular; Ce | 2014 |
XPD could suppress growth of HepG2.2.15 and down-regulate the expression of hepatitis B virus x protein through P53 pathway.
Topics: bcl-2-Associated X Protein; Benzothiazoles; Carcinoma, Hepatocellular; Cell Proliferation; Cell Surv | 2012 |
Differential protection and transactivation of P53, P21, Bcl2, PCNA, cyclin G, and MDM2 genes in rat liver and the HepG2 cell line upon exposure to pifithrin.
Topics: Animals; Arsenic; Benzothiazoles; Cadmium; Cell Line, Tumor; Cells, Cultured; Cytoprotection; DNA Da | 2007 |
Histone deacetylase inhibitors induce in human hepatoma HepG2 cells acetylation of p53 and histones in correlation with apoptotic effects.
Topics: Acetylation; Antineoplastic Agents; Apoptosis; Benzothiazoles; Carcinoma, Hepatocellular; Cell Line, | 2008 |