pifithrin has been researched along with Ischemic Stroke in 1 studies
pifithrin: a tetrahydrobenzothiazol; inhibitor of P53 that protects mice from the side effects of cancer therapy; structure in first source
Ischemic Stroke: Stroke due to BRAIN ISCHEMIA resulting in interruption or reduction of blood flow to a part of the brain. When obstruction is due to a BLOOD CLOT formed within in a cerebral blood vessel it is a thrombotic stroke. When obstruction is formed elsewhere and moved to block a cerebral blood vessel (see CEREBRAL EMBOLISM) it is referred to as embolic stroke. Wake-up stroke refers to ischemic stroke occurring during sleep while cryptogenic stroke refers to ischemic stroke of unknown origin.
| Excerpt | Relevance | Reference |
|---|---|---|
| "PFT-α inhibited neurological deficits, brain infarct volume, neuroinflammation, apoptosis, and BBB integrity than the MCAO/R rats; however, this inhibition was reversed by DKK1." | 1.91 | PFT-α protects the blood-brain barrier through the Wnt/β-catenin pathway after acute ischemic stroke. ( Du, D; Gao, X; Li, Z; Liu, P; Tian, X; Wang, B; Xu, Y; Yang, S; Zhang, H, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, H | 1 |
| Du, D | 1 |
| Gao, X | 1 |
| Tian, X | 1 |
| Xu, Y | 1 |
| Wang, B | 1 |
| Yang, S | 1 |
| Liu, P | 1 |
| Li, Z | 1 |
1 other study available for pifithrin and Ischemic Stroke
| Article | Year |
|---|---|
PFT-α protects the blood-brain barrier through the Wnt/β-catenin pathway after acute ischemic stroke.
Topics: Animals; beta Catenin; Blood-Brain Barrier; Brain Infarction; Endothelial Cells; Fluorescein; Ischem | 2023 |