pifithrin has been researched along with Ischemia in 2 studies
pifithrin: a tetrahydrobenzothiazol; inhibitor of P53 that protects mice from the side effects of cancer therapy; structure in first source
Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Renal ischemia reperfusion injury is known to shorten telomeres and upregulate stress-induced genes, such as the cyclin-dependent kinase (CDK) inhibitor p21." | 1.34 | p21 and mTERT are novel markers for determining different ischemic time periods in renal ischemia-reperfusion injury. ( Heininger, D; Hochegger, K; Huber, JM; Koppelstaetter, C; Mayer, G; Rosenkranz, AR; Tagwerker, A, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dagher, PC | 1 |
| Mai, EM | 1 |
| Hato, T | 1 |
| Lee, SY | 1 |
| Anderson, MD | 1 |
| Karozos, SC | 1 |
| Mang, HE | 1 |
| Knipe, NL | 1 |
| Plotkin, Z | 1 |
| Sutton, TA | 1 |
| Hochegger, K | 1 |
| Koppelstaetter, C | 1 |
| Tagwerker, A | 1 |
| Huber, JM | 1 |
| Heininger, D | 1 |
| Mayer, G | 1 |
| Rosenkranz, AR | 1 |
2 other studies available for pifithrin and Ischemia
| Article | Year |
|---|---|
The p53 inhibitor pifithrin-α can stimulate fibrosis in a rat model of ischemic acute kidney injury.
Topics: Acute Kidney Injury; Animals; Benzothiazoles; Fibrosis; Ischemia; Kidney; Male; Rats; Rats, Sprague- | 2012 |
p21 and mTERT are novel markers for determining different ischemic time periods in renal ischemia-reperfusion injury.
Topics: Animals; Benzothiazoles; Biomarkers; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase | 2007 |