pifithrin has been researched along with Hypoxia-Ischemia, Brain in 3 studies
pifithrin: a tetrahydrobenzothiazol; inhibitor of P53 that protects mice from the side effects of cancer therapy; structure in first source
Hypoxia-Ischemia, Brain: A disorder characterized by a reduction of oxygen in the blood combined with reduced blood flow (ISCHEMIA) to the brain from a localized obstruction of a cerebral artery or from systemic hypoperfusion. Prolonged hypoxia-ischemia is associated with ISCHEMIC ATTACK, TRANSIENT; BRAIN INFARCTION; BRAIN EDEMA; COMA; and other conditions.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nijboer, CH | 1 |
| Heijnen, CJ | 1 |
| van der Kooij, MA | 1 |
| Zijlstra, J | 1 |
| van Velthoven, CT | 1 |
| Culmsee, C | 1 |
| van Bel, F | 1 |
| Hagberg, H | 1 |
| Kavelaars, A | 1 |
| Tu, YF | 1 |
| Lu, PJ | 1 |
| Huang, CC | 1 |
| Ho, CJ | 1 |
| Chou, YP | 1 |
| Xu, FL | 1 |
| Zhu, CL | 1 |
| Wang, XY | 1 |
| Qiu, L | 1 |
| Ji, L | 1 |
| Cheng, XY | 1 |
| Luan, B | 1 |
3 other studies available for pifithrin and Hypoxia-Ischemia, Brain
| Article | Year |
|---|---|
Targeting the p53 pathway to protect the neonatal ischemic brain.
Topics: Animals; Animals, Newborn; Apoptosis; Benzothiazoles; Biomarkers; Brain; Hypoxia-Ischemia, Brain; Mi | 2011 |
Moderate dietary restriction reduces p53-mediated neurovascular damage and microglia activation after hypoxic ischemia in neonatal brain.
Topics: Animals; Animals, Newborn; Apoptosis; Benzothiazoles; Blood-Brain Barrier; Blotting, Western; Body W | 2012 |
[Expression of p53 in neonatal mice following hypoxia-ischemia and effects of its inhibitor on neonatal brain injury].
Topics: Animals; Animals, Newborn; Benzothiazoles; Brain; Dose-Response Relationship, Drug; Female; Hypoxia- | 2006 |