pifithrin has been researched along with Colorectal Cancer in 3 studies
pifithrin: a tetrahydrobenzothiazol; inhibitor of P53 that protects mice from the side effects of cancer therapy; structure in first source
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study, we chose human colorectal adenocarcinoma cell line HT-29 as the experimental model, and investigated the differential biological effects between 250 mGy single dose LDIR and 250 mGy intermittent LDIR pretreatments in high dose irradiation (HDIR) radiotherapy and 5-fluorouracil (5-FU) based chemotherapy." | 3.85 | Intermittent low dose irradiation enhances the effectiveness of radio- and chemo-therapy for human colorectal adenocarcinoma cell line HT-29. ( Li, Y; Wang, Y; Yang, L; Yin, D, 2017) |
| "5-Fluorouracil (5-FU) is a chemotherapeutic agent used in the treatment of colorectal cancer." | 3.85 | 5-Fluorouracil inhibits cell migration by induction of Sestrin2 in colon cancer cells. ( Ki, SH; Park, EY; Seo, K; Shin, SM, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Y | 1 |
| Li, Y | 1 |
| Yang, L | 1 |
| Yin, D | 1 |
| Jaiswal, AS | 1 |
| Panda, H | 1 |
| Law, BK | 1 |
| Sharma, J | 1 |
| Jani, J | 1 |
| Hromas, R | 1 |
| Narayan, S | 1 |
| Seo, K | 1 |
| Ki, SH | 1 |
| Park, EY | 1 |
| Shin, SM | 1 |
3 other studies available for pifithrin and Colorectal Cancer
| Article | Year |
|---|---|
Intermittent low dose irradiation enhances the effectiveness of radio- and chemo-therapy for human colorectal adenocarcinoma cell line HT-29.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Ataxia Telangiectasia Mutated Proteins; Benzothiazo | 2017 |
NSC666715 and Its Analogs Inhibit Strand-Displacement Activity of DNA Polymerase β and Potentiate Temozolomide-Induced DNA Damage, Senescence and Apoptosis in Colorectal Cancer Cells.
Topics: Apoptosis; Benzothiazoles; Cell Cycle; Cell Cycle Checkpoints; Cellular Senescence; Colorectal Neopl | 2015 |
5-Fluorouracil inhibits cell migration by induction of Sestrin2 in colon cancer cells.
Topics: Antimetabolites, Antineoplastic; Antioxidants; Benzothiazoles; Cell Movement; Colorectal Neoplasms; | 2017 |