pifithrin has been researched along with Cardiovascular Stroke in 4 studies
pifithrin: a tetrahydrobenzothiazol; inhibitor of P53 that protects mice from the side effects of cancer therapy; structure in first source
| Excerpt | Relevance | Reference |
|---|---|---|
| "Exposure to isoflurane before and during early reperfusion protects against myocardial infarction by activating phosphatidylinositol-3-kinase (PI3K)-mediated signaling." | 3.73 | Inhibition of apoptotic protein p53 lowers the threshold of isoflurane-induced cardioprotection during early reperfusion in rabbits. ( Kersten, JR; Krolikowski, JG; Pagel, PS; Pratt, PF; Venkatapuram, S; Wang, C; Warltier, DC; Weihrauch, D, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yano, T | 1 |
| Abe, K | 1 |
| Tanno, M | 1 |
| Miki, T | 1 |
| Kuno, A | 1 |
| Miura, T | 1 |
| Steenbergen, C | 1 |
| Zhang, Y | 1 |
| Köhler, K | 1 |
| Xu, J | 1 |
| Lu, D | 1 |
| Braun, T | 1 |
| Schlitt, A | 1 |
| Buerke, M | 1 |
| Müller-Werdan, U | 1 |
| Werdan, K | 1 |
| Ebelt, H | 1 |
| Mocanu, MM | 1 |
| Yellon, DM | 1 |
| Venkatapuram, S | 1 |
| Wang, C | 1 |
| Krolikowski, JG | 1 |
| Weihrauch, D | 1 |
| Kersten, JR | 1 |
| Warltier, DC | 1 |
| Pratt, PF | 1 |
| Pagel, PS | 1 |
4 other studies available for pifithrin and Cardiovascular Stroke
| Article | Year |
|---|---|
Does p53 Inhibition Suppress Myocardial Ischemia-Reperfusion Injury?
Topics: Animals; Benzothiazoles; Disease Models, Animal; Male; Mice, Inbred C57BL; Mice, Knockout; Myocardia | 2018 |
Inhibition of p53 after acute myocardial infarction: reduction of apoptosis is counteracted by disturbed scar formation and cardiac rupture.
Topics: Animals; Apoptosis; Benzothiazoles; Cell Proliferation; Cells, Cultured; Collagen; Heart Rupture; Hy | 2011 |
p53 down-regulation: a new molecular mechanism involved in ischaemic preconditioning.
Topics: Androstadienes; Animals; Benzothiazoles; Blotting, Northern; Down-Regulation; Enzyme Inhibitors; Isc | 2003 |
Inhibition of apoptotic protein p53 lowers the threshold of isoflurane-induced cardioprotection during early reperfusion in rabbits.
Topics: Animals; Benzothiazoles; Glycogen Synthase Kinases; Ischemic Preconditioning, Myocardial; Isoflurane | 2006 |