pifithrin has been researched along with Carcinoma in 5 studies
pifithrin: a tetrahydrobenzothiazol; inhibitor of P53 that protects mice from the side effects of cancer therapy; structure in first source
Carcinoma: A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We explored the effect of the combination of the histone deacetylase inhibitor ST2782 and the proteasome inhibitor bortezomib in ovarian carcinoma cell lines, including the IGROV-1 cell line and two p53 mutant platinum-resistant sublines (IGROV-1/OHP and IGROV-1/Pt1)." | 7.78 | Synergistic interaction between the novel histone deacetylase inhibitor ST2782 and the proteasome inhibitor bortezomib in platinum-sensitive and resistant ovarian carcinoma cells. ( Benedetti, V; Cincinelli, R; Corna, E; De Cesare, M; Gatti, L; Perego, P; Zaffaroni, N; Zunino, F, 2012) |
| " We explored the effect of the combination of the histone deacetylase inhibitor ST2782 and the proteasome inhibitor bortezomib in ovarian carcinoma cell lines, including the IGROV-1 cell line and two p53 mutant platinum-resistant sublines (IGROV-1/OHP and IGROV-1/Pt1)." | 3.78 | Synergistic interaction between the novel histone deacetylase inhibitor ST2782 and the proteasome inhibitor bortezomib in platinum-sensitive and resistant ovarian carcinoma cells. ( Benedetti, V; Cincinelli, R; Corna, E; De Cesare, M; Gatti, L; Perego, P; Zaffaroni, N; Zunino, F, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shi, C | 1 |
| Guan, Y | 1 |
| Zeng, L | 1 |
| Liu, G | 1 |
| Zhu, Y | 1 |
| Xu, H | 1 |
| Lu, Y | 1 |
| Liu, J | 1 |
| Guo, J | 1 |
| Feng, X | 1 |
| Zhao, X | 1 |
| Jiang, W | 1 |
| Li, G | 2 |
| Dai, Y | 1 |
| Jin, F | 1 |
| Li, W | 1 |
| Zhou, W | 1 |
| Struckhoff, AP | 1 |
| Patel, B | 1 |
| Beckman, BS | 1 |
| Gatti, L | 1 |
| Benedetti, V | 1 |
| De Cesare, M | 1 |
| Corna, E | 1 |
| Cincinelli, R | 1 |
| Zaffaroni, N | 1 |
| Zunino, F | 1 |
| Perego, P | 1 |
| Kuo, PC | 1 |
| Liu, HF | 1 |
| Chao, JI | 1 |
| Plísková, M | 1 |
| Vondrácek, J | 1 |
| Vojtesek, B | 1 |
| Kozubík, A | 1 |
| Machala, M | 1 |
5 other studies available for pifithrin and Carcinoma
| Article | Year |
|---|---|
High COX-2 expression contributes to a poor prognosis through the inhibition of chemotherapy-induced senescence in nasopharyngeal carcinoma.
Topics: Animals; Antineoplastic Agents; Benzothiazoles; Biomarkers, Tumor; Carcinoma; Cell Line, Tumor; Cell | 2018 |
Inhibition of p53 sensitizes MCF-7 cells to ceramide treatment.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzothiazoles; Breast Neoplasms; Carcino | 2010 |
Synergistic interaction between the novel histone deacetylase inhibitor ST2782 and the proteasome inhibitor bortezomib in platinum-sensitive and resistant ovarian carcinoma cells.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-2-Associated X | 2012 |
Survivin and p53 modulate quercetin-induced cell growth inhibition and apoptosis in human lung carcinoma cells.
Topics: Apoptosis; Benzothiazoles; Blotting, Western; Carcinoma; Cell Cycle; Cell Cycle Proteins; Cell Line, | 2004 |
Deregulation of cell proliferation by polycyclic aromatic hydrocarbons in human breast carcinoma MCF-7 cells reflects both genotoxic and nongenotoxic events.
Topics: Benz(a)Anthracenes; Benzo(a)pyrene; Benzothiazoles; Breast Neoplasms; Bromodeoxyuridine; Carcinogens | 2005 |