pifithrin has been researched along with Astrocytoma in 1 studies
pifithrin: a tetrahydrobenzothiazol; inhibitor of P53 that protects mice from the side effects of cancer therapy; structure in first source
Astrocytoma: Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Astrocytic tumors are the most common brain tumors with various genetic defects." | 1.35 | Axin induces cell death and reduces cell proliferation in astrocytoma by activating the p53 pathway. ( Chen, GS; Gu, Y; Li, FF; Li, H; Li, Q; Liu, F; Ye, J; Zhang, F; Zhang, LY, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, LY | 1 |
| Ye, J | 1 |
| Zhang, F | 1 |
| Li, FF | 1 |
| Li, H | 1 |
| Gu, Y | 1 |
| Liu, F | 1 |
| Chen, GS | 1 |
| Li, Q | 1 |
1 other study available for pifithrin and Astrocytoma
| Article | Year |
|---|---|
Axin induces cell death and reduces cell proliferation in astrocytoma by activating the p53 pathway.
Topics: Adolescent; Adult; Aged; Animals; Apoptosis; Astrocytoma; Axin Protein; Benzothiazoles; Brain Neopla | 2009 |