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pifithrin and Astrocytoma

pifithrin has been researched along with Astrocytoma in 1 studies

pifithrin: a tetrahydrobenzothiazol; inhibitor of P53 that protects mice from the side effects of cancer therapy; structure in first source

Astrocytoma: Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)

Research Excerpts

ExcerptRelevanceReference
"Astrocytic tumors are the most common brain tumors with various genetic defects."1.35Axin induces cell death and reduces cell proliferation in astrocytoma by activating the p53 pathway. ( Chen, GS; Gu, Y; Li, FF; Li, H; Li, Q; Liu, F; Ye, J; Zhang, F; Zhang, LY, 2009)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhang, LY1
Ye, J1
Zhang, F1
Li, FF1
Li, H1
Gu, Y1
Liu, F1
Chen, GS1
Li, Q1

Other Studies

1 other study available for pifithrin and Astrocytoma

ArticleYear
Axin induces cell death and reduces cell proliferation in astrocytoma by activating the p53 pathway.
    International journal of oncology, 2009, Volume: 35, Issue:1

    Topics: Adolescent; Adult; Aged; Animals; Apoptosis; Astrocytoma; Axin Protein; Benzothiazoles; Brain Neopla

2009