Page last updated: 2024-11-02

pifithrin and Abnormalities, Autosome

pifithrin has been researched along with Abnormalities, Autosome in 4 studies

pifithrin: a tetrahydrobenzothiazol; inhibitor of P53 that protects mice from the side effects of cancer therapy; structure in first source

Research Excerpts

Excerpt	Relevance	Reference
"Apoptosis and chromosomal aberrations were quantified at later sampling times following irradiation."	1.36	Relation between DNA repair, apoptosis and chromosomal aberrations in presence of pifithrin-alpha, an inhibitor of p53. ( Berni, A; Mancinelli, P; Meschini, R; Ortenzi, V; Palitti, F, 2010)

4 other studies available for pifithrin and Abnormalities, Autosome

Article	Year
Relation between DNA repair, apoptosis and chromosomal aberrations in presence of pifithrin-alpha, an inhibitor of p53. Mutation research, 2010, Aug-14, Volume: 701, Issue:1 Topics: Alpha Particles; Apoptosis; Benzothiazoles; Chromosome Aberrations; DNA Repair; Humans; Linear Energ	2010
Study on X-ray-induced apoptosis and chromosomal damage in G2 human lymphocytes in the presence of pifithrin-α, an inhibitor of p53. Mutation research, 2011, Nov-27, Volume: 726, Issue:1 Topics: Apoptosis; Benzothiazoles; Cells, Cultured; Chromosome Aberrations; DNA Repair; G2 Phase; Humans; Ly	2011
Inhibition of p73 function by Pifithrin-alpha as revealed by studies in zebrafish embryos. Cell cycle (Georgetown, Tex.), 2008, May-01, Volume: 7, Issue:9 Topics: Animals; Apoptosis; Benzothiazoles; Cell Survival; Chromosome Aberrations; DNA Damage; Down-Regulati	2008
Pifithrin-alpha, an inhibitor of p53, enhances the genetic instability induced by etoposide (VP16) in human lymphoblastoid cells treated in vitro. Mutation research, 2002, Feb-20, Volume: 499, Issue:2 Topics: Antineoplastic Agents, Phytogenic; Benzothiazoles; Cell Cycle; Cell Survival; Chromosome Aberrations	2002