Page last updated: 2024-08-23

picrotoxin and Down Syndrome

picrotoxin has been researched along with Down Syndrome in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (57.14)29.6817
2010's2 (28.57)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Barker, S; Costa, ACS; Faber, J; Pinheiro, DJLL; Scorza, CA; Scott-McKean, JJ; Stasko, MR; Victorino, DB1
Costa, ACS; Johnson, MW; Roque, AL; Scott-McKean, JJ; Surewicz, K; Surewicz, WK1
Underwood, E1
Belichenko, PV; Epstein, CJ; Kleschevnikov, AM; Malenka, RC; Mobley, WC; Villar, AJ1
Costa, AC; Grybko, MJ1
Blank, M; Fernandez, F; Garner, CC; Malenka, RC; Morishita, W; Nguyen, J; Zuniga, E1
Buckley, F; Sacks, B1

Other Studies

7 other study(ies) available for picrotoxin and Down Syndrome

ArticleYear
Atypical electrophysiological and behavioral responses to diazepam in a leading mouse model of Down syndrome.
    Scientific reports, 2021, 05-04, Volume: 11, Issue:1

    Topics: Animals; Diazepam; Disease Models, Animal; Down Syndrome; Electrophysiological Phenomena; Female; Long-Term Potentiation; Male; Maze Learning; Memory Disorders; Mice; Mice, Inbred C57BL; Neuronal Plasticity; Picrotoxin; Seizures; Synaptic Transmission

2021
Pharmacological Modulation of Three Modalities of CA1 Hippocampal Long-Term Potentiation in the Ts65Dn Mouse Model of Down Syndrome.
    Neural plasticity, 2018, Volume: 2018

    Topics: Amyloid beta-Peptides; Animals; CA1 Region, Hippocampal; Disease Models, Animal; Down Syndrome; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; Humans; Long-Term Potentiation; Male; Memantine; Mice, Inbred C57BL; Mice, Transgenic; Picrotoxin; Prion Proteins

2018
Can Down syndrome be treated?
    Science (New York, N.Y.), 2014, Feb-28, Volume: 343, Issue:6174

    Topics: Adult; Animals; Brain; Child; Chromosomes, Human, Pair 21; Clinical Trials as Topic; Cognition Disorders; Down Syndrome; Early Medical Intervention; Female; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Male; Mice; Mutagenesis, Insertional; Picrotoxin; RNA, Long Noncoding

2014
Hippocampal long-term potentiation suppressed by increased inhibition in the Ts65Dn mouse, a genetic model of Down syndrome.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Sep-15, Volume: 24, Issue:37

    Topics: 2-Amino-5-phosphonovalerate; Animals; Cognition Disorders; Crosses, Genetic; Dentate Gyrus; Disease Models, Animal; Down Syndrome; Evoked Potentials; Female; GABA-A Receptor Antagonists; Gene Dosage; Glycine; Hippocampus; Long-Term Potentiation; Magnesium; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Mutant Strains; Patch-Clamp Techniques; Picrotoxin; Presynaptic Terminals; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Species Specificity; Trisomy

2004
Deficits in hippocampal CA1 LTP induced by TBS but not HFS in the Ts65Dn mouse: a model of Down syndrome.
    Neuroscience letters, 2005, Jul-15, Volume: 382, Issue:3

    Topics: Animals; Disease Models, Animal; Down Syndrome; Electric Stimulation; Excitatory Postsynaptic Potentials; GABA Antagonists; Hippocampus; Long-Term Potentiation; Male; Mice; Organ Culture Techniques; Picrotoxin; Synaptic Transmission

2005
Pharmacotherapy for cognitive impairment in a mouse model of Down syndrome.
    Nature neuroscience, 2007, Volume: 10, Issue:4

    Topics: Animals; Behavior, Animal; Cognition Disorders; Disease Models, Animal; Down Syndrome; Electric Stimulation; Excitatory Postsynaptic Potentials; Exploratory Behavior; Female; GABA Antagonists; Hippocampus; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Neurons; Pentylenetetrazole; Picrotoxin

2007
Drug treatment improves memory in mice.
    Down's syndrome, research and practice : the journal of the Sarah Duffen Centre, 2007, Volume: 12, Issue:1

    Topics: Animals; Central Nervous System Stimulants; Chromosomes, Human, Pair 21; Cyclopentanes; Disease Models, Animal; Down Syndrome; Furans; GABA Antagonists; Ginkgolides; Humans; Maze Learning; Memory; Mice; Mice, Transgenic; Neuropsychological Tests; Pentylenetetrazole; Picrotoxin

2007