picrotoxin has been researched along with Anxiety in 40 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (12.50) | 18.7374 |
| 1990's | 7 (17.50) | 18.2507 |
| 2000's | 20 (50.00) | 29.6817 |
| 2010's | 7 (17.50) | 24.3611 |
| 2020's | 1 (2.50) | 2.80 |
| Authors | Studies |
|---|---|
| Du, JY; Fang, JF; Fang, JQ; Jin, XM; Liang, Y; Liu, JG; Qiu, MT; Shao, FB; Shao, XM; Shen, Z; Wang, SS; Xi, DN | 1 |
| Anilakumar, KR; Chandrasekhar, Y; Navya, K; Phani Kumar, G; Ramya, EM | 1 |
| Dong, J; Li, X; Yao, Y; Zhang, A; Zhu, X | 1 |
| Arya, J; Balakrishnan, S; Girish, C; Raj, V | 1 |
| Bai, Y; Chang, F; Chen, F; Chen, L; Zhou, R | 1 |
| Hassel, JE; Lowry, CA; Spiacci, A; Yamashita, PS; Zangrossi, H | 1 |
| Cao, X; Dahlhaus, R; El-Husseini, A; Hines, DJ; Hines, RM; Hormuzdi, SG; Mansour, S; Sammler, E; Singaraja, RR; Steenland, H; Wu, L; Zhuo, M | 1 |
| Christianson, JP; Maier, SF; Thompson, BM; Watkins, LR | 1 |
| Goyal, R; Kumar, A; Prakash, A | 1 |
| Kumar, A; Singh, A | 2 |
| Cristino, L; Di Marzo, V; Drago, F; Leggio, GM; Micale, V; Petrosino, S; Tamburella, A | 1 |
| Kumar, A; Kumar, P; Singh, A | 1 |
| Carro-Juárez, M; García-Orduña, F; Rodríguez-Landa, JF; Rodríguez-Peña, Mde L; Rovirosa-Hernández, Mde J | 1 |
| Briones-Aranda, A; López-Rubalcava, C; Picazo, O | 1 |
| Bernardi, MM; Spinosa, Hde S; Stilck, SR | 1 |
| Depaulis, A; Lê-Pham, BT; Marescaux, C; Nail-Boucherie, K | 1 |
| Goncharenko, NV; Pankrat'ev, DV; Talalaenko, AN | 1 |
| CUPARENCU, B; DAMACUS, M; GROSU, L | 1 |
| Bidziński, A; Członkowska, AI; Lehner, M; Maciejak, P; Płaźnik, A; Siemiatkowski, M; Sienkiewicz-Jarosz, H; Szyndler, J; Turzyńska, D; Wisłowska, A; Zienowicz, M | 1 |
| Estrada-Reyes, R; Heinze, G; López-Rubalcava, C; Martínez-Vázquez, M; Piña-Medina, B | 1 |
| Andreatini, R; Dombrowski, PA; Fernandes, LH | 1 |
| Camilo Flório, J; Palermo-Neto, J; Rodrigues-Costa, EC; Stankevicius, D | 1 |
| Gillardin, JM; Heulard, I; Verleye, M | 1 |
| Colwell, DD; Kavaliers, M | 1 |
| Matsuda, H; Matsumoto, K; Osanai, M; Shimada, T; Terasawa, K; Watanabe, H | 1 |
| Katner, JS; Shekhar, A | 1 |
| Bernardi, MM; Felicio, LF; Nasello, AG; Silva, MR | 1 |
| Sanders, SK; Shekhar, A | 1 |
| Chen, SW; Davies, MF; Loew, GH; Rodriguez, L | 1 |
| Audette, D; Bitran, D; Foley, M; Frye, CA; Leslie, N | 1 |
| Marta, CB; Medina, JH; Pasquini, JM; Soto, EF; Viola, H | 1 |
| Dalvi, A; Rodgers, RJ | 1 |
| Gordienko, DV; Krivobok, GK; Pankrat'ev, DV; Talalaenko, AN; Zinkovich, II | 1 |
| Popik, P; Wróbel, M | 1 |
| DiMicco, JA; Hingtgen, JN; Shekhar, A | 1 |
| Bhadra, S; Idemudia, SO; Lal, H | 1 |
| File, SE | 1 |
| Gray, JA; Henney, S; Lawson, P; Mellanby, J; Quintero, S | 1 |
| Buckland, C; Gray, JA; Mellanby, J | 1 |
1 review(s) available for picrotoxin and Anxiety
| Article | Year |
|---|---|
The contribution of behavioural studies to the neuropharmacology of anxiety.
Topics: Adrenocorticotropic Hormone; Animals; Anxiety; Behavior, Animal; Binding Sites; Carbolines; Chlorides; Neuropharmacology; Norepinephrine; Picrotoxin; Pyrazoles; Receptors, GABA-A; Serotonin | 1987 |
39 other study(ies) available for picrotoxin and Anxiety
| Article | Year |
|---|---|
Anxiolytic effect of GABAergic neurons in the anterior cingulate cortex in a rat model of chronic inflammatory pain.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Central Nervous System Sensitization; Chronic Pain; Clozapine; Freund's Adjuvant; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABAergic Neurons; Genetic Vectors; Gyrus Cinguli; Inflammation; Injections; Interneurons; Male; Muscimol; Open Field Test; Pain Threshold; Patch-Clamp Techniques; Picrotoxin; Presynaptic Terminals; Pyramidal Cells; Rats; Rats, Sprague-Dawley | 2021 |
Tannins from Terminalia chebula fruits attenuates GABA antagonist-induced anxiety-like behaviour via modulation of neurotransmitters.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine; Electroencephalography; Fruit; GABA Antagonists; Gene Expression; Locomotion; Mice; Neurotransmitter Agents; Norepinephrine; Picrotoxin; Plant Extracts; RNA, Messenger; Serotonin; Tannins; Terminalia | 2018 |
Alteration of GABAergic signaling is associated with anxiety-like behavior in temporal lobe epilepsy mice.
Topics: Animals; Anxiety; Blotting, Western; Disease Models, Animal; Epilepsy, Temporal Lobe; GABAergic Neurons; Hippocampus; Male; Maze Learning; Mice; Mice, Inbred C57BL; Muscimol; Picrotoxin; Pilocarpine; Real-Time Polymerase Chain Reaction; Receptors, GABA-A | 2019 |
Involvement of the GABAergic system in the anxiolytic-like effect of the flavonoid ellagic acid in mice.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Dose-Response Relationship, Drug; Ellagic Acid; Flumazenil; GABA-A Receptor Antagonists; Male; Mice; Motor Activity; Picrotoxin; Receptors, GABA-A | 2013 |
Persistent overexpression of DNA methyltransferase 1 attenuating GABAergic inhibition in basolateral amygdala accounts for anxiety in rat offspring exposed perinatally to low-dose bisphenol A.
Topics: Air Pollutants, Occupational; Amygdala; Animals; Anxiety; Benzhydryl Compounds; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Evoked Potentials; Female; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation, Enzymologic; Glutamate Decarboxylase; In Vitro Techniques; Indolizines; Male; Methionine; Neural Inhibition; Neurons; Phenols; Picrotoxin; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley | 2013 |
Disinhibition of the rat prelimbic cortex promotes serotonergic activation of the dorsal raphe nucleus and panicolytic-like behavioral effects.
Topics: Animals; Anxiety; Anxiety Disorders; Behavior, Animal; Dorsal Raphe Nucleus; Escape Reaction; gamma-Aminobutyric Acid; Male; Panic; Panic Disorder; Periaqueductal Gray; Picrotoxin; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Serotonin | 2017 |
Synaptic imbalance, stereotypies, and impaired social interactions in mice with altered neuroligin 2 expression.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Cell Adhesion Molecules, Neuronal; Chlorocebus aethiops; COS Cells; Electroencephalography; Inhibitory Postsynaptic Potentials; Interpersonal Relations; Membrane Proteins; Mice; Mice, Transgenic; Microscopy, Electron, Transmission; Nerve Tissue Proteins; Patch-Clamp Techniques; Picrotoxin; Prefrontal Cortex; Pyramidal Cells; Stereotyped Behavior; Synapses; Transfection; Vesicular Glutamate Transport Proteins | 2008 |
Medial prefrontal cortical activation modulates the impact of controllable and uncontrollable stressor exposure on a social exploration test of anxiety in the rat.
Topics: Animals; Anxiety; Behavior, Animal; Electroshock; Escape Reaction; Exploratory Behavior; Helplessness, Learned; Male; Muscimol; Picrotoxin; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Stress, Physiological; Stress, Psychological | 2009 |
Possible GABAergic mechanism in the protective effect of allopregnenolone against immobilization stress.
Topics: Animals; Anxiety; Behavior, Animal; GABA Agents; Immobilization; Mice; Muscimol; Oxidative Stress; Picrotoxin; Pregnenolone; Stereoisomerism; Stress, Psychological | 2009 |
Possible GABAergic modulation in the protective effect of allopregnanolone on sleep deprivation-induced anxiety-like behavior and oxidative damage in mice.
Topics: Animals; Anxiety; Behavior, Animal; Body Weight; Catalase; Dose-Response Relationship, Drug; Flumazenil; GABA Agonists; GABA Antagonists; GABA Modulators; Glutathione; Lipid Peroxidation; Male; Maze Learning; Mice; Motor Activity; Muscimol; Neuroprotective Agents; Nitrites; Oxidative Stress; Picrotoxin; Pregnanolone; Sleep Deprivation | 2008 |
Altered responses of dopamine D3 receptor null mice to excitotoxic or anxiogenic stimuli: Possible involvement of the endocannabinoid and endovanilloid systems.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anti-Inflammatory Agents, Non-Steroidal; Anxiety; Arachidonic Acids; Brain; Cannabinoid Receptor Modulators; Capsaicin; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Endocannabinoids; Epilepsy; GABA Antagonists; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Knockout; Picrotoxin; Piperidines; Pyrazoles; Reaction Time; Receptor, Cannabinoid, CB1; Receptors, Dopamine D3; Serotonin; TRPV Cation Channels | 2009 |
Possible involvement of GABAergic mechanism in protective effect of melatonin against sleep deprivation-induced behaviour modification and oxidative damage in mice.
Topics: Animals; Antioxidants; Anxiety; Behavior, Animal; Body Weight; Dose-Response Relationship, Drug; Female; Flumazenil; GABA Agonists; GABA Antagonists; GABA Modulators; Lipid Peroxidation; Male; Maze Learning; Melatonin; Mice; Motor Activity; Muscimol; Oxidative Stress; Picrotoxin; Sleep Deprivation | 2009 |
Possible involvement of GABAergic mechanism in protective effect of melatonin against sleep deprivation-induced behavior modification and oxidative damage in mice.
Topics: Animals; Antioxidants; Anxiety; Behavior, Animal; Flumazenil; GABA Modulators; gamma-Aminobutyric Acid; Lipid Peroxidation; Male; Melatonin; Mice; Motor Activity; Muscimol; Oxidative Stress; Picrotoxin; Sleep Deprivation | 2011 |
The aqueous crude extract of Montanoa frutescens produces anxiolytic-like effects similarly to diazepam in Wistar rats: involvement of GABAA receptor.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Diazepam; GABA Antagonists; Male; Montanoa; Motor Activity; Phytotherapy; Picrotoxin; Plant Extracts; Rats; Rats, Wistar; Receptors, GABA-A; Water | 2012 |
Influence of forced swimming-induced stress on the anxiolytic-like effect of 5HT(1A) agents in mice.
Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Buspirone; GABA Antagonists; Injections, Intraperitoneal; Male; Mice; Picrotoxin; Piperazines; Pyridines; Receptors, GABA-A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists; Stress, Psychological; Swimming | 2002 |
Possible anxiolytic effects of ivermectin in rats.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Behavior, Animal; Diazepam; Ivermectin; Locomotion; Male; Picrotoxin; Rats; Rats, Wistar; Seizures | 2002 |
Suppression of absence seizures by electrical and pharmacological activation of the caudal superior colliculus in a genetic model of absence epilepsy in the rat.
Topics: Animals; Anxiety; Behavior, Animal; Disease Models, Animal; Electric Stimulation Therapy; Electroencephalography; Epilepsy, Absence; Fear; GABA Antagonists; GABA-A Receptor Antagonists; Genetic Predisposition to Disease; Male; Maze Learning; Microinjections; Neural Inhibition; Picrotoxin; Rats; Rats, Inbred Strains; Superior Colliculi; Treatment Outcome; Water Deprivation | 2002 |
Neurochemical characteristics of the ventromedial hypothalamus in mediating the antiaversive effects of anxiolytics in different models of anxiety.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Apomorphine; Avoidance Learning; Biguanides; Brain Chemistry; Chlordiazepoxide; Clonidine; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Droperidol; Drug Interactions; GABA Agents; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Glutamic Acid; Male; Memantine; Mephenytoin; Microinjections; Pentylenetetrazole; Phentolamine; Picrotoxin; Piperazines; Propranolol; Pyrimidines; Rats; Serotonin; Sulpiride; Ventromedial Hypothalamic Nucleus; Yohimbine | 2003 |
The influence of certain drugs with a predominant central nervous action on protein assimilation and disassimilation.
Topics: Amphetamine; Amphetamines; Anxiety; Barbiturates; Chlorpromazine; Humans; Picrotoxin; Proteins | 1961 |
Rat behavior in two models of anxiety and brain [3H]muscimol binding: pharmacological, correlation, and multifactor analysis.
Topics: Analysis of Variance; Animals; Anxiety; Autoradiography; Behavior, Animal; Binding Sites; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Exploratory Behavior; Factor Analysis, Statistical; Fear; GABA Agonists; GABA Antagonists; GABA Modulators; Male; Midazolam; Muscimol; Picrotoxin; Rats; Rats, Wistar; Time Factors; Tritium | 2003 |
Anxiolytic-like actions of the hexane extract from leaves of Annona cherimolia in two anxiety paradigms: possible involvement of the GABA/benzodiazepine receptor complex.
Topics: Animals; Annona; Anti-Anxiety Agents; Anxiety; Anxiety Disorders; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; GABA Agonists; GABA Antagonists; Hexanes; Male; Mice; Muscimol; Picrotoxin; Plant Extracts; Plant Leaves; Receptors, GABA-A | 2006 |
Picrotoxin blocks the anxiolytic- and panicolytic-like effects of sodium valproate in the rat elevated T-maze.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Avoidance Learning; Escape Reaction; GABA Antagonists; Male; Motor Activity; Panic; Picrotoxin; Rats; Rats, Wistar; Valproic Acid | 2006 |
Neuroendocrine, behavioral and macrophage activity changes induced by picrotoxin effects in mice.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Brain Chemistry; Corticosterone; Diazepam; Flow Cytometry; GABA Antagonists; Hypothalamus; Immunity, Innate; Macrophages, Alveolar; Methoxyhydroxyphenylglycol; Mice; Neurosecretory Systems; Norepinephrine; Picrotoxin; Prefrontal Cortex; Respiratory Burst; Stress, Psychological | 2008 |
Investigation of the anticonvulsive effect of acute immobilization stress in anxious Balb/cByJ mice using GABA A-related mechanistic probes.
Topics: Allosteric Regulation; Animals; Anxiety; Bridged Bicyclo Compounds, Heterocyclic; Clonazepam; Convulsants; Drug Interactions; Finasteride; Isoquinolines; Male; Mice; Mice, Inbred BALB C; Oxazines; Picrotoxin; Pregnanolone; Progesterone; Receptors, GABA-A; Restraint, Physical; Seizures; Stress, Psychological | 2008 |
Decreased predator avoidance in parasitized mice: neuromodulatory correlates.
Topics: Animals; Anxiety; Avoidance Learning; Bicuculline; Cats; Coccidiosis; Dizocilpine Maleate; Eimeria; Flumazenil; GABA Antagonists; GABA-A Receptor Antagonists; Male; Mice; N-Methylaspartate; Naloxone; Odorants; Picrotoxin; Predatory Behavior; Receptors, GABA-A | 1995 |
The modified light/dark transition test in mice: evaluation of classic and putative anxiolytic and anxiogenic drugs.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Anxiety; Carbolines; Darkness; Light; Male; Methamphetamine; Mice; Motor Activity; Picrotoxin; Yohimbine | 1995 |
Dorsomedial hypothalamic GABA regulates anxiety in the social interaction test.
Topics: Animals; Anxiety; Atenolol; Atropine Derivatives; Bicuculline; Blood Pressure; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Heart Rate; Hypothalamus, Middle; Male; Microinjections; Muscimol; Parasympatholytics; Picrotoxin; Rats; Rats, Sprague-Dawley; Social Behavior | 1995 |
Is perinatal picrotoxin anxiogenic?
Topics: Animals; Anxiety; Behavior, Animal; Central Nervous System Stimulants; Female; Male; Motor Activity; Picrotoxin; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar | 1995 |
Regulation of anxiety by GABAA receptors in the rat amygdala.
Topics: Amygdala; Animals; Anxiety; Bicuculline; Interpersonal Relations; Male; Muscimol; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A | 1995 |
The hyperphagic effect of 3 alpha-hydroxylated pregnane steroids in male rats.
Topics: Animals; Anxiety; Dose-Response Relationship, Drug; Eating; Feeding Behavior; Flumazenil; GABA Antagonists; GABA Modulators; GABA-A Receptor Antagonists; Male; Picrotoxin; Pregnanes; Pregnanolone; Rats; Rats, Sprague-Dawley | 1996 |
Activation of peripheral mitochondrial benzodiazepine receptors in the hippocampus stimulates allopregnanolone synthesis and produces anxiolytic-like effects in the rat.
Topics: Analysis of Variance; Animals; Anxiety; GABA Antagonists; Hippocampus; Indoleacetic Acids; Isoquinolines; Male; Mitochondria; Picrotoxin; Pregnanolone; Rats; Rats, Long-Evans; Receptors, GABA-A | 2000 |
Anxiolytic-like behavior in rats is induced by the neonatal intracranial injection of apotransferrin.
Topics: Animals; Animals, Newborn; Anxiety; Apoproteins; Behavior, Animal; Brain; GABA Antagonists; Male; Maze Learning; Motor Activity; Myelin Sheath; Oligodendroglia; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Transferrin | 2001 |
Anxiolytic effects of valproate and diazepam in mice are differentially sensitive to picrotoxin antagonism.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Decision Making; Diazepam; Exploratory Behavior; GABA Antagonists; Male; Mice; Mice, Inbred DBA; Motor Activity; Picrotoxin; Valproic Acid | 2001 |
The role of neurochemical mechanisms of ventromedial hypothalamus in various models of anxiety in rats.
Topics: Adrenergic Agents; Animals; Anxiety; Apomorphine; Avoidance Learning; Disease Models, Animal; Dopamine; Dopamine Agents; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hypothalamus, Middle; Male; Memantine; Microinjections; Neurotransmitter Agents; Phenylephrine; Picrotoxin; Rats; Serotonin; Sulpiride; Yohimbine | 2001 |
Anxiogenic action of ibogaine.
Topics: Animals; Anxiety; Ibogaine; Male; Maze Learning; Mice; Picrotoxin | 2001 |
GABA receptors in the posterior hypothalamus regulate experimental anxiety in rats.
Topics: Animals; Anxiety; Bicuculline; Heart Rate; Hypothalamus; Hypothalamus, Posterior; Male; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1990 |
The pentylenetetrazol-like interoceptive stimulus produced by ethanol withdrawal is potentiated by bicuculline and picrotoxinin.
Topics: Animals; Anxiety; Bicuculline; Discrimination Learning; Dose-Response Relationship, Drug; Ethanol; GABA Antagonists; Male; Pentylenetetrazole; Picrotoxin; Rats; Seizures; Sesterterpenes; Substance Withdrawal Syndrome | 1989 |
The effects of compounds related to gamma-aminobutyrate and benzodiazepine receptors on behavioural responses to anxiogenic stimuli in the rat: punished barpressing.
Topics: Amobarbital; Animals; Anti-Anxiety Agents; Anxiety; Baclofen; Bicuculline; Carbolines; Chlordiazepoxide; Drug Interactions; Humans; Male; Muscimol; Neural Inhibition; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptic Transmission | 1985 |
The effects of compounds related to gamma-aminobutyrate and benzodiazepine receptors on behavioural responses to anxiogenic stimuli in the rat: extinction and successive discrimination.
Topics: Animals; Anxiety; Baclofen; Behavior, Animal; Bicuculline; Chlordiazepoxide; Discrimination Learning; Discrimination, Psychological; Drug Interactions; Extinction, Psychological; Male; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Time Factors | 1986 |