picolinic acid has been researched along with Smith-Lemli-Opitz Syndrome in 1 studies
picolinic acid: iron-chelating agent that inhibits DNA synthesis; may interfere with iron-dependent production of stable free organic radical which is essential for ribonucleotide reductase formation of deoxyribonucleotides; RN given refers to parent cpd; structure in Merck Index, 9th ed, #7206
picolinic acid : A pyridinemonocarboxylic acid in which the carboxy group is located at position 2. It is an intermediate in the metabolism of tryptophan.
Smith-Lemli-Opitz Syndrome: An autosomal recessive disorder of CHOLESTEROL metabolism. It is caused by a deficiency of 7-dehydrocholesterol reductase, the enzyme that converts 7-dehydrocholesterol to cholesterol, leading to an abnormally low plasma cholesterol. This syndrome is characterized by multiple CONGENITAL ABNORMALITIES, growth deficiency, and INTELLECTUAL DISABILITY.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Honda, A | 1 |
| Yamashita, K | 1 |
| Miyazaki, H | 1 |
| Shirai, M | 1 |
| Ikegami, T | 1 |
| Xu, G | 1 |
| Numazawa, M | 1 |
| Hara, T | 1 |
| Matsuzaki, Y | 1 |
1 other study available for picolinic acid and Smith-Lemli-Opitz Syndrome
| Article | Year |
|---|---|
Highly sensitive analysis of sterol profiles in human serum by LC-ESI-MS/MS.
Topics: Caco-2 Cells; Chondrodysplasia Punctata; Chromatography, Liquid; Humans; Picolinic Acids; Reproducib | 2008 |