Page last updated: 2024-10-20

picolinic acid and Pregnancy

picolinic acid has been researched along with Pregnancy in 16 studies

picolinic acid: iron-chelating agent that inhibits DNA synthesis; may interfere with iron-dependent production of stable free organic radical which is essential for ribonucleotide reductase formation of deoxyribonucleotides; RN given refers to parent cpd; structure in Merck Index, 9th ed, #7206
picolinic acid : A pyridinemonocarboxylic acid in which the carboxy group is located at position 2. It is an intermediate in the metabolism of tryptophan.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"Chromium (Cr) is a micromineral that is involved in the metabolism of carbohydrates, lipids, ammonia, and nucleic acids; thus, its supplementation can influence the nutritional status of ruminants, and consequently, colostrum profile, since this secretion depends on products secreted by the mammary gland and elements of the maternal bloodstream."1.56Long-term chromium picolinate supplementation improves colostrum profile of Santa Ines ewe. ( Abdalla, AL; Bompadre, TFV; Fernandes, EAN; Ieda, EH; Louvandini, H; Machado-Neto, R; Martinez, MIV; Moretti, DB; Sakita, GZ, 2020)
" The results showed that no pathological, toxic feces and urine changes were observed in clinical signs of parental and fetal rats in chromium malate groups."1.42Evaluation of the Reproductive Toxicity, Glycometabolism, Glycometabolism-Related Enzyme Levels and Lipid Metabolism of Chromium Malate Supplementation in Sprague-Dawley Rats. ( Bao, Y; Feng, W; Huang, J; Mao, G; Wang, W; Wu, X; Yang, L; Zhang, W; Zhao, T; Zhou, Z, 2015)
" Dams were sacrificed on GD 17, and their litters were examined for adverse effects."1.35Comparison of the potential for developmental toxicity of prenatal exposure to two dietary chromium supplements, chromium picolinate and [Cr3O(O2CCH2CH3)(6(H2O)3]+, in mice. ( Ankareddi, I; Bailey, MM; Bushman, J; Hood, RD; Jernigan, PL; Rasco, JF; Sturdivant, J; Townsend, MB; Vincent, JB, 2008)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19905 (31.25)18.7374
1990's1 (6.25)18.2507
2000's5 (31.25)29.6817
2010's4 (25.00)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Shi, Z2
Song, W1
Sun, Y1
Wang, L2
Shi, B2
Shan, A2
Bi, Z1
Bompadre, TFV1
Moretti, DB1
Sakita, GZ1
Ieda, EH1
Martinez, MIV1
Fernandes, EAN1
Machado-Neto, R1
Abdalla, AL1
Louvandini, H1
Jia, Z1
Su, B1
Zavitsanou, K1
Lim, CK1
Purves-Tyson, T1
Karl, T1
Kassiou, M1
Banister, SD1
Guillemin, GJ1
Weickert, CS1
Feng, W1
Zhang, W1
Zhao, T1
Mao, G1
Wang, W1
Wu, X2
Zhou, Z1
Huang, J1
Bao, Y1
Yang, L1
Young, MG1
Tokach, MD2
Noblet, J1
Aherne, FX1
Dritz, SS2
Goodband, RD2
Nelssen, JL2
van Milgen, J1
Woodworth, JC2
Bailey, MM3
Boohaker, JG2
Sawyer, RD1
Behling, JE1
Rasco, JF3
Jernigan, JJ1
Hood, RD3
Vincent, JB3
Koo, SI1
Minton, JE1
Owen, KQ1
Sturdivant, J2
Jernigan, PL2
Townsend, MB2
Bushman, J1
Ankareddi, I1
van Winkle, LJ1
Doman, DR1
Campione, AL1
Hurley, LS1
Lönnerdal, B1
May, PM1
Smith, GL1
Williams, DR1
Lindemann, MD1
Wood, CM1
Harper, AF1
Kornegay, ET1
Anderson, RA1
Jendryczko, A2
Drózdz, M2
Magner, K1

Reviews

1 review available for picolinic acid and Pregnancy

ArticleYear
Zinc binding in human milk: citrate versus picolinate.
    Nutrition reviews, 1982, Volume: 40, Issue:3

    Topics: Absorption; Animals; Cattle; Citrates; Female; Humans; Infant; Infant, Newborn; Ligands; Milk; Milk,

1982

Other Studies

15 other studies available for picolinic acid and Pregnancy

ArticleYear
Dietary supplementation of l-arginine and chromium picolinate in sows during gestation affects the muscle fibre characteristics but not the performance of their progeny.
    Journal of the science of food and agriculture, 2018, Volume: 98, Issue:1

    Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Arginine; Birth Weight; Dietary Su

2018
Long-term chromium picolinate supplementation improves colostrum profile of Santa Ines ewe.
    Biological trace element research, 2020, Volume: 193, Issue:2

    Topics: Animals; Animals, Newborn; Catalase; Ceruloplasmin; Chromium; Colostrum; Dietary Supplements; Female

2020
The effects of dietary supplementation with chromium picolinate throughout gestation on productive performance, Cr concentration, serum parameters, and colostrum composition in sows.
    Biological trace element research, 2013, Volume: 154, Issue:1

    Topics: Animals; Animals, Newborn; Birth Weight; Blood Chemical Analysis; Chromium; Colostrum; Dietary Suppl

2013
Effect of maternal immune activation on the kynurenine pathway in preadolescent rat offspring and on MK801-induced hyperlocomotion in adulthood: amelioration by COX-2 inhibition.
    Brain, behavior, and immunity, 2014, Volume: 41

    Topics: Animals; Brain; Celecoxib; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Dizocilpine Maleate;

2014
Evaluation of the Reproductive Toxicity, Glycometabolism, Glycometabolism-Related Enzyme Levels and Lipid Metabolism of Chromium Malate Supplementation in Sprague-Dawley Rats.
    Biological trace element research, 2015, Volume: 168, Issue:1

    Topics: Animals; Chromium Compounds; Diabetes Mellitus, Experimental; Dietary Supplements; Dose-Response Rel

2015
Influence of Carnichrome on the energy balance of gestating sows.
    Journal of animal science, 2004, Volume: 82, Issue:7

    Topics: Animals; Body Temperature Regulation; Calorimetry, Indirect; Carnitine; Digestion; Drug Synergism; E

2004
Exposure of pregnant mice to chromium picolinate results in skeletal defects in their offspring.
    Birth defects research. Part B, Developmental and reproductive toxicology, 2006, Volume: 77, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Cervical Vertebrae; Female; Mice; Picolinic Acids; Pregnancy;

2006
Influence of dietary L-carnitine and chromium picolinate on blood hormones and metabolites of gestating sows fed one meal per day.
    Journal of animal science, 2007, Volume: 85, Issue:10

    Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Blood Urea Nitrogen; C-Peptide; Ca

2007
Comparison of the potential for developmental toxicity of prenatal exposure to two dietary chromium supplements, chromium picolinate and [Cr3O(O2CCH2CH3)(6(H2O)3]+, in mice.
    Birth defects research. Part B, Developmental and reproductive toxicology, 2008, Volume: 83, Issue:1

    Topics: Administration, Oral; Animals; Dietary Supplements; Dose-Response Relationship, Drug; Embryonic Deve

2008
Effects of pre- and postnatal exposure to chromium picolinate or picolinic acid on neurological development in CD-1 mice.
    Biological trace element research, 2008, Volume: 124, Issue:1

    Topics: Animals; Biophysical Phenomena; Biophysics; Female; Forelimb; Hippocampus; Male; Maternal Exposure;

2008
Effects of dietary picolinate on mice deprived of tryptophan, niacin and vitamin B-6.
    Journal of nutritional science and vitaminology, 1983, Volume: 29, Issue:6

    Topics: Animals; Blastocyst; Body Weight; Diet; Female; Mice; Niacin; Picolinic Acids; Pregnancy; Tryptophan

1983
Computer calculation of zinc(II)-complex distribution in milk.
    The Journal of nutrition, 1982, Volume: 112, Issue:10

    Topics: Animals; Cattle; Citrates; Computers; Female; Glutamates; Ligands; Milk; Milk, Human; Molecular Weig

1982
Dietary chromium picolinate additions improve gain:feed and carcass characteristics in growing-finishing pigs and increase litter size in reproducing sows.
    Journal of animal science, 1995, Volume: 73, Issue:2

    Topics: Animal Feed; Animals; Body Composition; Crosses, Genetic; Diet; Eating; Female; Litter Size; Male; P

1995
[Picolinic acid concentration in human milk].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1985, Jan-14, Volume: 40, Issue:2

    Topics: Adult; Age Factors; Female; Humans; Milk, Human; Picolinic Acids; Pregnancy

1985
[Picolinic acid level in human milk].
    Pediatria polska, 1985, Volume: 60, Issue:7

    Topics: Female; Humans; Milk, Human; Picolinic Acids; Postpartum Period; Pregnancy

1985