picolinic acid has been researched along with Metabolic Syndrome in 5 studies
picolinic acid: iron-chelating agent that inhibits DNA synthesis; may interfere with iron-dependent production of stable free organic radical which is essential for ribonucleotide reductase formation of deoxyribonucleotides; RN given refers to parent cpd; structure in Merck Index, 9th ed, #7206
picolinic acid : A pyridinemonocarboxylic acid in which the carboxy group is located at position 2. It is an intermediate in the metabolism of tryptophan.
Metabolic Syndrome: A cluster of symptoms that are risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components of metabolic syndrome include ABDOMINAL OBESITY; atherogenic DYSLIPIDEMIA; HYPERTENSION; HYPERGLYCEMIA; INSULIN RESISTANCE; a proinflammatory state; and a prothrombotic (THROMBOSIS) state.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metabolic syndrome is defined by a cluster of cardiovascular disease risk factors that are associated with insulin resistance." | 2.47 | Alternative and complementary treatments for metabolic syndrome. ( Power, M; Pratley, R, 2011) |
| "To evaluate whether CrPic may aid in treatment of the insulin resistance syndrome, we assessed its effects in JCR:LA-corpulent rats, a model of this syndrome." | 1.31 | Oral chromium picolinate improves carbohydrate and lipid metabolism and enhances skeletal muscle Glut-4 translocation in obese, hyperinsulinemic (JCR-LA corpulent) rats. ( Baldor, LC; Cefalu, WT; Russell, JC; Wang, ZQ; Zhang, XH, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cicero, AF | 1 |
| Tartagni, E | 1 |
| Ertek, S | 1 |
| Iqbal, N | 1 |
| Cardillo, S | 1 |
| Volger, S | 1 |
| Bloedon, LT | 1 |
| Anderson, RA | 1 |
| Boston, R | 1 |
| Szapary, PO | 1 |
| Power, M | 1 |
| Pratley, R | 1 |
| Proctor, SD | 1 |
| Kelly, SE | 1 |
| Stanhope, KL | 1 |
| Havel, PJ | 1 |
| Russell, JC | 2 |
| Cefalu, WT | 1 |
| Wang, ZQ | 1 |
| Zhang, XH | 1 |
| Baldor, LC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Double-Blind Randomized Controlled Clinical Trial of Chromium Picolinate on Clinical and Biochemical Features of the Metabolic Syndrome[NCT00128154] | 60 participants | Interventional | 2004-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for picolinic acid and Metabolic Syndrome
| Article | Year |
|---|---|
Nutraceuticals for metabolic syndrome management: from laboratory to benchside.
Topics: Animals; Berberine; Body Weight; Cardiovascular Diseases; Cinnamomum zeylanicum; Dietary Supplements | 2014 |
Alternative and complementary treatments for metabolic syndrome.
Topics: Animals; Cinnamomum zeylanicum; Humans; Insulin Resistance; Metabolic Syndrome; Picolinic Acids; Pla | 2011 |
1 trial available for picolinic acid and Metabolic Syndrome
| Article | Year |
|---|---|
Chromium picolinate does not improve key features of metabolic syndrome in obese nondiabetic adults.
Topics: Academic Medical Centers; Adult; Aged; Blood Glucose; C-Reactive Protein; Double-Blind Method; Femal | 2009 |
2 other studies available for picolinic acid and Metabolic Syndrome
| Article | Year |
|---|---|
Synergistic effects of conjugated linoleic acid and chromium picolinate improve vascular function and renal pathophysiology in the insulin-resistant JCR:LA-cp rat.
Topics: Adiponectin; Albuminuria; Animals; Aorta; Body Weight; Diabetic Nephropathies; Dose-Response Relatio | 2007 |
Oral chromium picolinate improves carbohydrate and lipid metabolism and enhances skeletal muscle Glut-4 translocation in obese, hyperinsulinemic (JCR-LA corpulent) rats.
Topics: Administration, Oral; Animals; Area Under Curve; Blood Glucose; Carbohydrate Metabolism; Diabetes Me | 2002 |