picolinic acid has been researched along with Innate Inflammatory Response in 9 studies
picolinic acid: iron-chelating agent that inhibits DNA synthesis; may interfere with iron-dependent production of stable free organic radical which is essential for ribonucleotide reductase formation of deoxyribonucleotides; RN given refers to parent cpd; structure in Merck Index, 9th ed, #7206
picolinic acid : A pyridinemonocarboxylic acid in which the carboxy group is located at position 2. It is an intermediate in the metabolism of tryptophan.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Inflammatory proteins are thought to be causally involved in the generation of aggression, possibly due to direct effects of cytokines in the central nervous system and/or by generation of inflammatory metabolites along the tryptophan-kynurenine (TRP/KYN) pathway, including KYN and its active metabolites kynurenic acid (KA), quinolinic acid (QA), and picolinic acid (PA)." | 7.83 | Tryptophan, kynurenine, and kynurenine metabolites: Relationship to lifetime aggression and inflammatory markers in human subjects. ( Brundin, L; Christensen, K; Coccaro, EF; Coussons-Read, M; Erhardt, S; Fanning, JR; Fuchs, D; Goiny, M; Lee, R, 2016) |
| " The kynurenine pathway (KP), activated during neuroinflammation, is emerging as a possible contributory factor in ALS." | 7.76 | The kynurenine pathway and inflammation in amyotrophic lateral sclerosis. ( Brew, BJ; Chen, Y; Coggan, S; Cullen, KM; Garner, B; Grant, R; Guillemin, GJ; Meininger, V; Stankovic, R, 2010) |
| "Primary deficit schizophrenia is accompanied by an activated TRYCAT pathway as compared to controls and nondeficit schizophrenia." | 5.48 | Deficit, but Not Nondeficit, Schizophrenia Is Characterized by Mucosa-Associated Activation of the Tryptophan Catabolite (TRYCAT) Pathway with Highly Specific Increases in IgA Responses Directed to Picolinic, Xanthurenic, and Quinolinic Acid. ( Anderson, G; Carvalho, AF; Geffard, M; Kanchanatawan, B; Maes, M; Ormstad, H; Ruxrungtham, K; Sirivichayakul, S, 2018) |
| "Inflammatory proteins are thought to be causally involved in the generation of aggression, possibly due to direct effects of cytokines in the central nervous system and/or by generation of inflammatory metabolites along the tryptophan-kynurenine (TRP/KYN) pathway, including KYN and its active metabolites kynurenic acid (KA), quinolinic acid (QA), and picolinic acid (PA)." | 3.83 | Tryptophan, kynurenine, and kynurenine metabolites: Relationship to lifetime aggression and inflammatory markers in human subjects. ( Brundin, L; Christensen, K; Coccaro, EF; Coussons-Read, M; Erhardt, S; Fanning, JR; Fuchs, D; Goiny, M; Lee, R, 2016) |
| " The kynurenine pathway (KP), activated during neuroinflammation, is emerging as a possible contributory factor in ALS." | 3.76 | The kynurenine pathway and inflammation in amyotrophic lateral sclerosis. ( Brew, BJ; Chen, Y; Coggan, S; Cullen, KM; Garner, B; Grant, R; Guillemin, GJ; Meininger, V; Stankovic, R, 2010) |
| "Primary deficit schizophrenia is accompanied by an activated TRYCAT pathway as compared to controls and nondeficit schizophrenia." | 1.48 | Deficit, but Not Nondeficit, Schizophrenia Is Characterized by Mucosa-Associated Activation of the Tryptophan Catabolite (TRYCAT) Pathway with Highly Specific Increases in IgA Responses Directed to Picolinic, Xanthurenic, and Quinolinic Acid. ( Anderson, G; Carvalho, AF; Geffard, M; Kanchanatawan, B; Maes, M; Ormstad, H; Ruxrungtham, K; Sirivichayakul, S, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 8 (88.89) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chia, EW | 1 |
| Pearce, AN | 1 |
| Berridge, MV | 1 |
| Larsen, L | 1 |
| Perry, NB | 1 |
| Sansom, CE | 1 |
| Godfrey, CA | 1 |
| Hanton, LR | 1 |
| Lu, GL | 1 |
| Walton, M | 1 |
| Denny, WA | 1 |
| Webb, VL | 1 |
| Copp, BR | 1 |
| Harper, JL | 1 |
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Heilman, P | 1 |
| Hill, MN | 1 |
| Coussons-Read, M | 2 |
| Brundin, L | 3 |
| Coccaro, EF | 2 |
| Al-Rasheed, NM | 2 |
| Attia, HA | 1 |
| Mohamed, RA | 1 |
| Al-Amin, MA | 1 |
| Zhou, J | 1 |
| Xu, H | 1 |
| Huang, K | 1 |
| Lee, R | 1 |
| Fanning, JR | 1 |
| Fuchs, D | 2 |
| Goiny, M | 1 |
| Erhardt, S | 2 |
| Christensen, K | 1 |
| Sellgren, CM | 1 |
| Lim, CK | 1 |
| Grit, J | 1 |
| Pålsson, E | 1 |
| Landén, M | 1 |
| Samuelsson, M | 1 |
| Lundgren, K | 1 |
| Brundin, P | 1 |
| Postolache, TT | 1 |
| Traskman-Bendz, L | 1 |
| Guillemin, GJ | 2 |
| Kanchanatawan, B | 1 |
| Sirivichayakul, S | 1 |
| Ruxrungtham, K | 1 |
| Carvalho, AF | 1 |
| Geffard, M | 1 |
| Ormstad, H | 1 |
| Anderson, G | 1 |
| Maes, M | 1 |
| Chen, Y | 1 |
| Stankovic, R | 1 |
| Cullen, KM | 1 |
| Meininger, V | 1 |
| Garner, B | 1 |
| Coggan, S | 1 |
| Grant, R | 1 |
| Brew, BJ | 1 |
1 review available for picolinic acid and Innate Inflammatory Response
| Article | Year |
|---|---|
Organoselenium Small Molecules and Chromium(III) Complexes for Intervention in Chronic Low-grade Inflammation and Type 2 Diabetes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Azoles; Chromium Compounds; Cysteine; Diabetes Mellitus, Ty | 2016 |
8 other studies available for picolinic acid and Innate Inflammatory Response
| Article | Year |
|---|---|
Synthesis and anti-inflammatory structure-activity relationships of thiazine-quinoline-quinones: inhibitors of the neutrophil respiratory burst in a model of acute gouty arthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Cell Proliferation; Disease Mode | 2008 |
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
Role of the kynurenine pathway and the endocannabinoid system as modulators of inflammation and personality traits.
Topics: Adult; Anxiety Disorders; Arachidonic Acids; Cohort Studies; Endocannabinoids; Female; Glycerides; H | 2019 |
Preventive effects of selenium yeast, chromium picolinate, zinc sulfate and their combination on oxidative stress, inflammation, impaired angiogenesis and atherogenesis in myocardial infarction in rats.
Topics: Animals; Atherosclerosis; Cardiotonic Agents; Drug Therapy, Combination; Dyslipidemias; Inflammation | 2013 |
Tryptophan, kynurenine, and kynurenine metabolites: Relationship to lifetime aggression and inflammatory markers in human subjects.
Topics: Adult; Aggression; Biomarkers; C-Reactive Protein; Female; Humans; Inflammation; Interleukin-6; Kynu | 2016 |
An enzyme in the kynurenine pathway that governs vulnerability to suicidal behavior by regulating excitotoxicity and neuroinflammation.
Topics: Adolescent; Adult; Aged; Alleles; Carboxy-Lyases; Case-Control Studies; Child; Female; Humans; Infla | 2016 |
Deficit, but Not Nondeficit, Schizophrenia Is Characterized by Mucosa-Associated Activation of the Tryptophan Catabolite (TRYCAT) Pathway with Highly Specific Increases in IgA Responses Directed to Picolinic, Xanthurenic, and Quinolinic Acid.
Topics: Adult; Cross-Sectional Studies; Female; Humans; Immunoglobulin A; Inflammation; Male; Middle Aged; P | 2018 |
The kynurenine pathway and inflammation in amyotrophic lateral sclerosis.
Topics: Adult; Amyotrophic Lateral Sclerosis; Brain; Female; HLA-DR Antigens; Humans; Indoleamine-Pyrrole 2, | 2010 |