picolinic acid has been researched along with Hyperkalemia in 1 studies
picolinic acid: iron-chelating agent that inhibits DNA synthesis; may interfere with iron-dependent production of stable free organic radical which is essential for ribonucleotide reductase formation of deoxyribonucleotides; RN given refers to parent cpd; structure in Merck Index, 9th ed, #7206
picolinic acid : A pyridinemonocarboxylic acid in which the carboxy group is located at position 2. It is an intermediate in the metabolism of tryptophan.
Hyperkalemia: Abnormally high potassium concentration in the blood, most often due to defective renal excretion. It is characterized clinically by electrocardiographic abnormalities (elevated T waves and depressed P waves, and eventually by atrial asystole). In severe cases, weakness and flaccid paralysis may occur. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Picolinic acid (PIC) is a byproduct of tryptophan catabolism through the kynurenine pathway, with anabolic effects on bone in vivo and in vitro." | 1.62 | Evaluating the toxicity of escalating dose of oral picolinic acid in Sprague-Dawley rats. ( Bani Hassan, E; Bienvenu, JG; Doyle, N; Duque, G; Guillemin, GJ; Stent, A, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bani Hassan, E | 1 |
| Doyle, N | 1 |
| Bienvenu, JG | 1 |
| Stent, A | 1 |
| Guillemin, GJ | 1 |
| Duque, G | 1 |
1 other study available for picolinic acid and Hyperkalemia
| Article | Year |
|---|---|
Evaluating the toxicity of escalating dose of oral picolinic acid in Sprague-Dawley rats.
Topics: Animals; Dose-Response Relationship, Drug; Hypercalcemia; Hyperkalemia; Male; Neurotoxicity Syndrome | 2021 |