picolinic acid has been researched along with Germinoblastoma in 2 studies
picolinic acid: iron-chelating agent that inhibits DNA synthesis; may interfere with iron-dependent production of stable free organic radical which is essential for ribonucleotide reductase formation of deoxyribonucleotides; RN given refers to parent cpd; structure in Merck Index, 9th ed, #7206
picolinic acid : A pyridinemonocarboxylic acid in which the carboxy group is located at position 2. It is an intermediate in the metabolism of tryptophan.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In order to study the mechanism of observed cellular toxicity and mutagenicity, chromium picolinate and its component compounds, chromium (III) chloride and picolinic acid, were evaluated in Salmonella typhimurium and L5178Y mouse lymphoma cells." | 7.73 | Mutagenicity of chromium picolinate and its components in Salmonella typhimurium and L5178Y mouse lymphoma cells. ( Clarke, JJ; Dunkel, VC; San, RH; Seifried, HE; Whittaker, P, 2005) |
| " In order to study the mechanism of observed cellular toxicity and mutagenicity, chromium picolinate and its component compounds, chromium (III) chloride and picolinic acid, were evaluated in Salmonella typhimurium and L5178Y mouse lymphoma cells." | 3.73 | Mutagenicity of chromium picolinate and its components in Salmonella typhimurium and L5178Y mouse lymphoma cells. ( Clarke, JJ; Dunkel, VC; San, RH; Seifried, HE; Whittaker, P, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Whittaker, P | 1 |
| San, RH | 1 |
| Clarke, JJ | 1 |
| Seifried, HE | 1 |
| Dunkel, VC | 1 |
| Ruffmann, R | 1 |
| Welker, RD | 1 |
| Saito, T | 1 |
| Chirigos, MA | 1 |
| Varesio, L | 1 |
2 other studies available for picolinic acid and Germinoblastoma
| Article | Year |
|---|---|
Mutagenicity of chromium picolinate and its components in Salmonella typhimurium and L5178Y mouse lymphoma cells.
Topics: Animals; Cell Line, Tumor; Cell Survival; Chromium; Cricetinae; In Vitro Techniques; Liver; Lymphoma | 2005 |
In vivo activation of macrophages but not natural killer cells by picolinic acid (PLA).
Topics: Animals; Cell Line; Cytotoxicity, Immunologic; Killer Cells, Natural; Leukemia, Experimental; Lympho | 1984 |