picolinic acid has been researched along with Dysthymic Disorder in 1 studies
picolinic acid: iron-chelating agent that inhibits DNA synthesis; may interfere with iron-dependent production of stable free organic radical which is essential for ribonucleotide reductase formation of deoxyribonucleotides; RN given refers to parent cpd; structure in Merck Index, 9th ed, #7206
picolinic acid : A pyridinemonocarboxylic acid in which the carboxy group is located at position 2. It is an intermediate in the metabolism of tryptophan.
Dysthymic Disorder: Chronically depressed mood that occurs for most of the day more days than not for at least 2 years. The required minimum duration in children to make this diagnosis is 1 year. During periods of depressed mood, at least 2 of the following additional symptoms are present: poor appetite or overeating, insomnia or hypersomnia, low energy or fatigue, low self-esteem, poor concentration or difficulty making decisions, and feelings of hopelessness. (DSM-IV)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Following a patient's report of dramatic response to the addition of chromium supplementation to sertraline pharmacotherapy for dysthymic disorder (DSM-IV), the authors initiated a series of single-blind and open-label trials of chromium picolinate or chromium polynicotinate in the treatment of antidepressant-refractory dysthymic disorder." | 9.09 | Chromium potentiation of antidepressant pharmacotherapy for dysthymic disorder in 5 patients. ( Gaynes, BN; Golden, RN; McLeod, MN, 1999) |
| "Following a patient's report of dramatic response to the addition of chromium supplementation to sertraline pharmacotherapy for dysthymic disorder (DSM-IV), the authors initiated a series of single-blind and open-label trials of chromium picolinate or chromium polynicotinate in the treatment of antidepressant-refractory dysthymic disorder." | 5.09 | Chromium potentiation of antidepressant pharmacotherapy for dysthymic disorder in 5 patients. ( Gaynes, BN; Golden, RN; McLeod, MN, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McLeod, MN | 1 |
| Gaynes, BN | 1 |
| Golden, RN | 1 |
1 trial available for picolinic acid and Dysthymic Disorder
| Article | Year |
|---|---|
Chromium potentiation of antidepressant pharmacotherapy for dysthymic disorder in 5 patients.
Topics: Adult; Antidepressive Agents; Ascorbic Acid; Chromium; Dietary Supplements; Drug Synergism; Drug The | 1999 |