picolinic acid has been researched along with Disease Models, Animal in 14 studies
picolinic acid: iron-chelating agent that inhibits DNA synthesis; may interfere with iron-dependent production of stable free organic radical which is essential for ribonucleotide reductase formation of deoxyribonucleotides; RN given refers to parent cpd; structure in Merck Index, 9th ed, #7206
picolinic acid : A pyridinemonocarboxylic acid in which the carboxy group is located at position 2. It is an intermediate in the metabolism of tryptophan.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hyperlipidemia is one of the major risk factors for atherosclerosis and ischemic heart disease." | 1.46 | Synergistic Cardioprotective Effects of Combined Chromium Picolinate and Atorvastatin Treatment in Triton X-100-Induced Hyperlipidemia in Rats: Impact on Some Biochemical Markers. ( Baalash, A; Ebeid, AM; Shafik, NM, 2017) |
| "Hallmark features of type 2 diabetes mellitus include glucosuria and polyuria." | 1.38 | Renal distal tubule proliferation and increased aquaporin 2 level but decreased urine osmolality in db/db mouse: treatment with chromium picolinate. ( Abdelsayed, R; Baban, B; Liu, JY; Mozaffari, MS; Zakhary, I, 2012) |
| "To evaluate whether CrPic may aid in treatment of the insulin resistance syndrome, we assessed its effects in JCR:LA-corpulent rats, a model of this syndrome." | 1.31 | Oral chromium picolinate improves carbohydrate and lipid metabolism and enhances skeletal muscle Glut-4 translocation in obese, hyperinsulinemic (JCR-LA corpulent) rats. ( Baldor, LC; Cefalu, WT; Russell, JC; Wang, ZQ; Zhang, XH, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.14) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (50.00) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Chia, EW | 1 |
| Pearce, AN | 1 |
| Berridge, MV | 1 |
| Larsen, L | 1 |
| Perry, NB | 1 |
| Sansom, CE | 1 |
| Godfrey, CA | 1 |
| Hanton, LR | 1 |
| Lu, GL | 1 |
| Walton, M | 1 |
| Denny, WA | 1 |
| Webb, VL | 1 |
| Copp, BR | 1 |
| Harper, JL | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Akhtar, A | 1 |
| Dhaliwal, J | 1 |
| Saroj, P | 1 |
| Uniyal, A | 1 |
| Bishnoi, M | 1 |
| Sah, SP | 1 |
| Shafik, NM | 1 |
| Baalash, A | 1 |
| Ebeid, AM | 1 |
| Zavitsanou, K | 1 |
| Lim, CK | 1 |
| Purves-Tyson, T | 1 |
| Karl, T | 1 |
| Kassiou, M | 1 |
| Banister, SD | 1 |
| Guillemin, GJ | 1 |
| Weickert, CS | 1 |
| Refaie, FM | 1 |
| Esmat, AY | 1 |
| Mohamed, AF | 1 |
| Aboul Nour, WH | 1 |
| Mozaffari, MS | 2 |
| Baban, B | 2 |
| Abdelsayed, R | 2 |
| Liu, JY | 2 |
| Wimborne, H | 1 |
| Rodriguez, N | 1 |
| Abebe, W | 1 |
| Zakhary, I | 1 |
| Clark, CJ | 1 |
| Mackay, GM | 1 |
| Smythe, GA | 1 |
| Bustamante, S | 1 |
| Stone, TW | 1 |
| Phillips, RS | 1 |
| Machaliński, B | 1 |
| Walczak, M | 1 |
| Syrenicz, A | 1 |
| Machalińska, A | 1 |
| Grymuła, K | 1 |
| Stecewicz, I | 1 |
| Wiszniewska, B | 1 |
| Dabkowska, E | 1 |
| Sahin, K | 1 |
| Onderci, M | 1 |
| Tuzcu, M | 1 |
| Ustundag, B | 1 |
| Cikim, G | 1 |
| Ozercan, IH | 1 |
| Sriramoju, V | 1 |
| Juturu, V | 1 |
| Komorowski, JR | 1 |
| Khanam, R | 1 |
| Pillai, KK | 1 |
| Lönnerdal, B | 1 |
| Keen, CL | 1 |
| Hurley, LS | 1 |
| Cefalu, WT | 1 |
| Wang, ZQ | 1 |
| Zhang, XH | 1 |
| Baldor, LC | 1 |
| Russell, JC | 1 |
1 review available for picolinic acid and Disease Models, Animal
| Article | Year |
|---|---|
Zinc binding ligands and complexes in zinc metabolism.
Topics: Acrodermatitis; Animals; Bile; Carrier Proteins; Cattle; Cattle Diseases; Chromatography, High Press | 1984 |
13 other studies available for picolinic acid and Disease Models, Animal
| Article | Year |
|---|---|
Synthesis and anti-inflammatory structure-activity relationships of thiazine-quinoline-quinones: inhibitors of the neutrophil respiratory burst in a model of acute gouty arthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Cell Proliferation; Disease Mode | 2008 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Chromium picolinate attenuates cognitive deficit in ICV-STZ rat paradigm of sporadic Alzheimer's-like dementia via targeting neuroinflammatory and IRS-1/PI3K/AKT/GSK-3β pathway.
Topics: Alzheimer Disease; Animals; Cognitive Dysfunction; Dementia; Disease Models, Animal; Dose-Response R | 2020 |
Synergistic Cardioprotective Effects of Combined Chromium Picolinate and Atorvastatin Treatment in Triton X-100-Induced Hyperlipidemia in Rats: Impact on Some Biochemical Markers.
Topics: Animals; Aorta; Atorvastatin; Biomarkers; C-Reactive Protein; Cardiotonic Agents; Chromium; Combined | 2017 |
Effect of maternal immune activation on the kynurenine pathway in preadolescent rat offspring and on MK801-induced hyperlocomotion in adulthood: amelioration by COX-2 inhibition.
Topics: Animals; Brain; Celecoxib; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Dizocilpine Maleate; | 2014 |
Effect of chromium supplementation on the diabetes induced-oxidative stress in liver and brain of adult rats.
Topics: Alloxan; Animals; Brain; Catalase; Chromium; Diabetes Mellitus; Diabetes Mellitus, Experimental; Dis | 2009 |
Renal and glycemic effects of high-dose chromium picolinate in db/db mice: assessment of DNA damage.
Topics: Albuminuria; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; DNA Breaks, | 2012 |
Renal distal tubule proliferation and increased aquaporin 2 level but decreased urine osmolality in db/db mouse: treatment with chromium picolinate.
Topics: Animals; Aquaporin 2; Biological Transport; Blood Glucose; Body Weight; Cell Proliferation; Dehydrat | 2012 |
Prolonged survival of a murine model of cerebral malaria by kynurenine pathway inhibition.
Topics: Animals; Chemokine CCL4; Disease Models, Animal; Kynurenine; Kynurenine 3-Monooxygenase; Macrophage | 2005 |
Hypoglycemic potency of novel trivalent chromium in hyperglycemic insulin-deficient rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Glucose; Body Weight; Cell Line; C | 2006 |
Effect of chromium on carbohydrate and lipid metabolism in a rat model of type 2 diabetes mellitus: the fat-fed, streptozotocin-treated rat.
Topics: Animals; Biomarkers; Body Weight; Carbohydrate Metabolism; Diabetes Mellitus, Experimental; Diet, At | 2007 |
Effect of chronic chromium picolinate in animal models of anxiety and memory.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Diabetes Mellitus, Experimental; Disease Mo | 2007 |
Oral chromium picolinate improves carbohydrate and lipid metabolism and enhances skeletal muscle Glut-4 translocation in obese, hyperinsulinemic (JCR-LA corpulent) rats.
Topics: Administration, Oral; Animals; Area Under Curve; Blood Glucose; Carbohydrate Metabolism; Diabetes Me | 2002 |