picolinic acid has been researched along with Depressive Disorder, Major in 2 studies
picolinic acid: iron-chelating agent that inhibits DNA synthesis; may interfere with iron-dependent production of stable free organic radical which is essential for ribonucleotide reductase formation of deoxyribonucleotides; RN given refers to parent cpd; structure in Merck Index, 9th ed, #7206
picolinic acid : A pyridinemonocarboxylic acid in which the carboxy group is located at position 2. It is an intermediate in the metabolism of tryptophan.
Depressive Disorder, Major: Disorder in which five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1) depressed mood or (2) loss of interest or pleasure. Symptoms include: depressed mood most of the day, nearly every daily; markedly diminished interest or pleasure in activities most of the day, nearly every day; significant weight loss when not dieting or weight gain; Insomnia or hypersomnia nearly every day; psychomotor agitation or retardation nearly every day; fatigue or loss of energy nearly every day; feelings of worthlessness or excessive or inappropriate guilt; diminished ability to think or concentrate, or indecisiveness, nearly every day; or recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt. (DSM-5)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Colle, R | 1 |
| Masson, P | 1 |
| Verstuyft, C | 1 |
| Fève, B | 1 |
| Werner, E | 1 |
| Boursier-Neyret, C | 1 |
| Walther, B | 1 |
| David, DJ | 1 |
| Boniface, B | 1 |
| Falissard, B | 1 |
| Chanson, P | 1 |
| Corruble, E | 1 |
| Becquemont, L | 1 |
| McIntyre, RS | 1 |
| Soczynska, JK | 1 |
| Lewis, GF | 1 |
| MacQueen, GM | 1 |
| Konarski, JZ | 1 |
| Kennedy, SH | 1 |
1 review available for picolinic acid and Depressive Disorder, Major
| Article | Year |
|---|---|
Managing psychiatric disorders with antidiabetic agents: translational research and treatment opportunities.
Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Animals; Bipolar Disorder; Brain; Cognition; Depr | 2006 |
1 other study available for picolinic acid and Depressive Disorder, Major
| Article | Year |
|---|---|
Peripheral tryptophan, serotonin, kynurenine, and their metabolites in major depression: A case-control study.
Topics: 3-Hydroxyanthranilic Acid; Adult; Case-Control Studies; Cohort Studies; Depressive Disorder, Major; | 2020 |