Page last updated: 2024-10-20

picolinic acid and Depression, Endogenous

picolinic acid has been researched along with Depression, Endogenous in 3 studies

picolinic acid: iron-chelating agent that inhibits DNA synthesis; may interfere with iron-dependent production of stable free organic radical which is essential for ribonucleotide reductase formation of deoxyribonucleotides; RN given refers to parent cpd; structure in Merck Index, 9th ed, #7206
picolinic acid : A pyridinemonocarboxylic acid in which the carboxy group is located at position 2. It is an intermediate in the metabolism of tryptophan.

Research Excerpts

ExcerptRelevanceReference
" (1) The chronic administration of isoniazid for the prevention or treatment of tuberculosis can produce peripheral neuropathy which can be prevented by the concurrent administration of pyridoxine."2.36Drug-pyridoxal phosphate interactions. ( Al-Sayegh, A; Ebadi, M; Gessert, CF, 1982)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davidson, JR1
Abraham, K1
Connor, KM1
McLeod, MN1
Docherty, JP1
Sack, DA1
Roffman, M1
Finch, M1
Komorowski, JR1
Ebadi, M1
Gessert, CF1
Al-Sayegh, A1

Reviews

1 review available for picolinic acid and Depression, Endogenous

ArticleYear
Drug-pyridoxal phosphate interactions.
    Quarterly reviews on drug metabolism and drug interactions, 1982, Volume: 4, Issue:4

    Topics: Animals; Contraceptives, Oral, Hormonal; Depressive Disorder; Disease; Drug Interactions; Drug Thera

1982

Trials

2 trials available for picolinic acid and Depression, Endogenous

ArticleYear
Effectiveness of chromium in atypical depression: a placebo-controlled trial.
    Biological psychiatry, 2003, Feb-01, Volume: 53, Issue:3

    Topics: Adult; Antidepressive Agents; Depressive Disorder; Double-Blind Method; Female; Humans; Male; Middle

2003
A double-blind, placebo-controlled, exploratory trial of chromium picolinate in atypical depression: effect on carbohydrate craving.
    Journal of psychiatric practice, 2005, Volume: 11, Issue:5

    Topics: Adult; Appetite; Depressive Disorder; Dietary Carbohydrates; Double-Blind Method; Female; Humans; Hy

2005