picolinic acid has been researched along with Colonic Neoplasms in 3 studies
picolinic acid: iron-chelating agent that inhibits DNA synthesis; may interfere with iron-dependent production of stable free organic radical which is essential for ribonucleotide reductase formation of deoxyribonucleotides; RN given refers to parent cpd; structure in Merck Index, 9th ed, #7206
picolinic acid : A pyridinemonocarboxylic acid in which the carboxy group is located at position 2. It is an intermediate in the metabolism of tryptophan.
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A lactoferrin receptor has been found on the brush-border membrane of intestinal epithelial cells of several species, including humans." | 1.29 | Effect of intracellular iron depletion by picolinic acid on expression of the lactoferrin receptor in the human colon carcinoma cell subclone HT29-18-C1. ( Marianne, T; Mikogami, T; Spik, G, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Poljarević, JM | 1 |
| Tamás Gál, G | 1 |
| May, NV | 1 |
| Spengler, G | 1 |
| Dömötör, O | 1 |
| Savić, AR | 1 |
| Grgurić-Šipka, S | 1 |
| Enyedy, ÉA | 1 |
| van Rijt, SH | 1 |
| Peacock, AF | 1 |
| Johnstone, RD | 1 |
| Parsons, S | 1 |
| Sadler, PJ | 1 |
| Mikogami, T | 1 |
| Marianne, T | 1 |
| Spik, G | 1 |
3 other studies available for picolinic acid and Colonic Neoplasms
| Article | Year |
|---|---|
Comparative solution equilibrium and structural studies of half-sandwich ruthenium(II)(η
Topics: Adenocarcinoma; Antineoplastic Agents; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Surviva | 2018 |
Organometallic osmium(II) arene anticancer complexes containing picolinate derivatives.
Topics: Antineoplastic Agents; Cell Line, Tumor; Colonic Neoplasms; Drug Stability; Female; Humans; Ligands; | 2009 |
Effect of intracellular iron depletion by picolinic acid on expression of the lactoferrin receptor in the human colon carcinoma cell subclone HT29-18-C1.
Topics: Biological Transport; Colonic Neoplasms; Humans; In Vitro Techniques; Intestinal Absorption; Intesti | 1995 |