Page last updated: 2024-10-20

picolinic acid and Colonic Neoplasms

picolinic acid has been researched along with Colonic Neoplasms in 3 studies

picolinic acid: iron-chelating agent that inhibits DNA synthesis; may interfere with iron-dependent production of stable free organic radical which is essential for ribonucleotide reductase formation of deoxyribonucleotides; RN given refers to parent cpd; structure in Merck Index, 9th ed, #7206
picolinic acid : A pyridinemonocarboxylic acid in which the carboxy group is located at position 2. It is an intermediate in the metabolism of tryptophan.

Colonic Neoplasms: Tumors or cancer of the COLON.

Research Excerpts

ExcerptRelevanceReference
"A lactoferrin receptor has been found on the brush-border membrane of intestinal epithelial cells of several species, including humans."1.29Effect of intracellular iron depletion by picolinic acid on expression of the lactoferrin receptor in the human colon carcinoma cell subclone HT29-18-C1. ( Marianne, T; Mikogami, T; Spik, G, 1995)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Poljarević, JM1
Tamás Gál, G1
May, NV1
Spengler, G1
Dömötör, O1
Savić, AR1
Grgurić-Šipka, S1
Enyedy, ÉA1
van Rijt, SH1
Peacock, AF1
Johnstone, RD1
Parsons, S1
Sadler, PJ1
Mikogami, T1
Marianne, T1
Spik, G1

Other Studies

3 other studies available for picolinic acid and Colonic Neoplasms

ArticleYear
Comparative solution equilibrium and structural studies of half-sandwich ruthenium(II)(η
    Journal of inorganic biochemistry, 2018, Volume: 181

    Topics: Adenocarcinoma; Antineoplastic Agents; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Surviva

2018
Organometallic osmium(II) arene anticancer complexes containing picolinate derivatives.
    Inorganic chemistry, 2009, Feb-16, Volume: 48, Issue:4

    Topics: Antineoplastic Agents; Cell Line, Tumor; Colonic Neoplasms; Drug Stability; Female; Humans; Ligands;

2009
Effect of intracellular iron depletion by picolinic acid on expression of the lactoferrin receptor in the human colon carcinoma cell subclone HT29-18-C1.
    The Biochemical journal, 1995, Jun-01, Volume: 308 ( Pt 2)

    Topics: Biological Transport; Colonic Neoplasms; Humans; In Vitro Techniques; Intestinal Absorption; Intesti

1995