Page last updated: 2024-10-20

picolinic acid and Chemical and Drug Induced Liver Injury

picolinic acid has been researched along with Chemical and Drug Induced Liver Injury in 4 studies

picolinic acid: iron-chelating agent that inhibits DNA synthesis; may interfere with iron-dependent production of stable free organic radical which is essential for ribonucleotide reductase formation of deoxyribonucleotides; RN given refers to parent cpd; structure in Merck Index, 9th ed, #7206
picolinic acid : A pyridinemonocarboxylic acid in which the carboxy group is located at position 2. It is an intermediate in the metabolism of tryptophan.

Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.

Research Excerpts

ExcerptRelevanceReference
"Trivalent chromium is an essential trace element that is considered safe when ingested in normal quantities."1.30Chromium picolinate toxicity. ( Cerulli, J; Gauthier, I; Grabe, DW; Malone, M; McGoldrick, MD, 1998)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strechen', SB1
Kresiun, VI1
Fan, W2
Chen, K1
Zheng, G2
Wang, W2
Teng, A2
Liu, A2
Ming, D1
Yan, P1
Cerulli, J1
Grabe, DW1
Gauthier, I1
Malone, M1
McGoldrick, MD1

Other Studies

4 other studies available for picolinic acid and Chemical and Drug Induced Liver Injury

ArticleYear
[Mechanisms of hepatoprotective action of new nicotinic acid derivatives in experimental CCL4-induced liver injury].
    Biulleten' eksperimental'noi biologii i meditsiny, 1992, Volume: 114, Issue:7

    Topics: Animals; Carbon Tetrachloride Poisoning; Catalase; Chemical and Drug Induced Liver Injury; Liver; Li

1992
Role of liver fatty acid binding protein in hepatocellular injury: effect of CrPic treatment.
    Journal of inorganic biochemistry, 2013, Volume: 124

    Topics: Alanine Transaminase; Alloxan; Animals; Chemical and Drug Induced Liver Injury; Diabetes Mellitus, E

2013
Hepatoprotective activity of CrPic against alloxan-induced hepatotoxicity in mice.
    Biological trace element research, 2012, Volume: 149, Issue:2

    Topics: Alloxan; Animals; Chemical and Drug Induced Liver Injury; Glutathione; Liver; Malondialdehyde; Mice;

2012
Chromium picolinate toxicity.
    The Annals of pharmacotherapy, 1998, Volume: 32, Issue:4

    Topics: Acute Kidney Injury; Adult; Blood Cell Count; Chemical and Drug Induced Liver Injury; Drug Overdose;

1998