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picolinic acid and Central Nervous System Diseases

picolinic acid has been researched along with Central Nervous System Diseases in 2 studies

picolinic acid: iron-chelating agent that inhibits DNA synthesis; may interfere with iron-dependent production of stable free organic radical which is essential for ribonucleotide reductase formation of deoxyribonucleotides; RN given refers to parent cpd; structure in Merck Index, 9th ed, #7206
picolinic acid : A pyridinemonocarboxylic acid in which the carboxy group is located at position 2. It is an intermediate in the metabolism of tryptophan.

Central Nervous System Diseases: Diseases of any component of the brain (including the cerebral hemispheres, diencephalon, brain stem, and cerebellum) or the spinal cord.

Research Excerpts

ExcerptRelevanceReference
"In patients with no apparent CNS disease, CSF PIC levels were 10-fold higher in samples taken between 20:00 and 16:00 h compared with those collected between 04:00 and 12:00 h."1.35Age and circadian influences on picolinic acid concentrations in human cerebrospinal fluid. ( Bilgin, A; Coggan, SE; Grant, RS; Smythe, GA, 2009)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Lin, SX1
Curtis, MA1
Sperry, J1
Coggan, SE1
Smythe, GA1
Bilgin, A1
Grant, RS1

Reviews

1 review available for picolinic acid and Central Nervous System Diseases

ArticleYear
Pyridine alkaloids with activity in the central nervous system.
    Bioorganic & medicinal chemistry, 2020, 12-15, Volume: 28, Issue:24

    Topics: Alkaloids; Amphibians; Animals; Bacteria; Central Nervous System Diseases; Fungi; Nicotine; Plants;

2020

Other Studies

1 other study available for picolinic acid and Central Nervous System Diseases

ArticleYear
Age and circadian influences on picolinic acid concentrations in human cerebrospinal fluid.
    Journal of neurochemistry, 2009, Volume: 108, Issue:5

    Topics: Aging; Analysis of Variance; C-Reactive Protein; Case-Control Studies; Central Nervous System Diseas

2009