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picolinic acid and Cell Transformation, Neoplastic

picolinic acid has been researched along with Cell Transformation, Neoplastic in 1 studies

picolinic acid: iron-chelating agent that inhibits DNA synthesis; may interfere with iron-dependent production of stable free organic radical which is essential for ribonucleotide reductase formation of deoxyribonucleotides; RN given refers to parent cpd; structure in Merck Index, 9th ed, #7206
picolinic acid : A pyridinemonocarboxylic acid in which the carboxy group is located at position 2. It is an intermediate in the metabolism of tryptophan.

Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gurley, LR1
Jett, JH1

Other Studies

1 other study available for picolinic acid and Cell Transformation, Neoplastic

ArticleYear
Cell cycle kinetics of Chinese hamster (CHO) cells treated with the iron-chelating agent picolinic acid.
    Cell and tissue kinetics, 1981, Volume: 14, Issue:3

    Topics: Animals; Autoradiography; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Cytological Techni

1981