picolinic acid has been researched along with Cancer of Prostate in 3 studies
picolinic acid: iron-chelating agent that inhibits DNA synthesis; may interfere with iron-dependent production of stable free organic radical which is essential for ribonucleotide reductase formation of deoxyribonucleotides; RN given refers to parent cpd; structure in Merck Index, 9th ed, #7206
picolinic acid : A pyridinemonocarboxylic acid in which the carboxy group is located at position 2. It is an intermediate in the metabolism of tryptophan.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Androgens play a vital role in prostate cancer development, and their elimination and blockade are essential in the disease management." | 1.48 | Simultaneous determination of dihydrotestosterone and its metabolites in mouse sera by LC-MS/MS with chemical derivatization. ( Gorityala, S; Montano, MM; Xu, Y; Yang, S, 2018) |
| "Castration resistant prostate cancer (CRPC), the fatal form of prostate cancer, remains androgen dependent despite castrate levels of circulating testosterone (T) and 5α-dihydrotestosterone (DHT)." | 1.46 | Simultaneous quantitation of nine hydroxy-androgens and their conjugates in human serum by stable isotope dilution liquid chromatography electrospray ionization tandem mass spectrometry. ( Blair, IA; Huang, M; Mesaros, C; Penning, TM; Tamae, D; Wang, Q; Zang, T, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Iikuni, S | 1 |
| Tarumizu, Y | 1 |
| Tsuchihashi, S | 1 |
| Ohara, T | 1 |
| Watanabe, H | 1 |
| Ono, M | 1 |
| Gorityala, S | 1 |
| Yang, S | 1 |
| Montano, MM | 1 |
| Xu, Y | 1 |
| Zang, T | 1 |
| Tamae, D | 1 |
| Mesaros, C | 1 |
| Wang, Q | 1 |
| Huang, M | 1 |
| Blair, IA | 1 |
| Penning, TM | 1 |
3 other studies available for picolinic acid and Cancer of Prostate
| Article | Year |
|---|---|
Synthesis and Evaluation of Novel
Topics: Albumins; Animals; Antigens, Surface; Cell Line, Tumor; Glutamate Carboxypeptidase II; Humans; Indiu | 2022 |
Simultaneous determination of dihydrotestosterone and its metabolites in mouse sera by LC-MS/MS with chemical derivatization.
Topics: Animals; Chromatography, Liquid; Dihydrotestosterone; Linear Models; Male; Mice; Picolinic Acids; Pr | 2018 |
Simultaneous quantitation of nine hydroxy-androgens and their conjugates in human serum by stable isotope dilution liquid chromatography electrospray ionization tandem mass spectrometry.
Topics: Androgens; Androstenediol; Calibration; Chromatography, Liquid; Female; Humans; Limit of Detection; | 2017 |