picolinic acid has been researched along with Body Weight in 36 studies
picolinic acid: iron-chelating agent that inhibits DNA synthesis; may interfere with iron-dependent production of stable free organic radical which is essential for ribonucleotide reductase formation of deoxyribonucleotides; RN given refers to parent cpd; structure in Merck Index, 9th ed, #7206
picolinic acid : A pyridinemonocarboxylic acid in which the carboxy group is located at position 2. It is an intermediate in the metabolism of tryptophan.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study tested the hypothesis that supplementation of chromium picolinate (CrPic), 200 microg Cr/d, compared with an equivalent amount of picolinic acid (1720 microg) in CrPic and placebo, decreases body weight, alters body composition, and reduces iron status of women fed diets of constant energy and nutrients." | 9.12 | Chromium picolinate supplementation in women: effects on body weight, composition, and iron status. ( Lukaski, HC; Penland, JG; Siders, WA, 2007) |
| " Tryp deficiency caused classical manifestations of pellagra although niacin intake was in excess of normal requirements." | 7.67 | Tryptophan deficiency and picolinic acid: effect on zinc metabolism and clinical manifestations of pellagra. ( Krieger, I; Statter, M, 1987) |
| "This study tested the hypothesis that supplementation of chromium picolinate (CrPic), 200 microg Cr/d, compared with an equivalent amount of picolinic acid (1720 microg) in CrPic and placebo, decreases body weight, alters body composition, and reduces iron status of women fed diets of constant energy and nutrients." | 5.12 | Chromium picolinate supplementation in women: effects on body weight, composition, and iron status. ( Lukaski, HC; Penland, JG; Siders, WA, 2007) |
| " Tryp deficiency caused classical manifestations of pellagra although niacin intake was in excess of normal requirements." | 3.67 | Tryptophan deficiency and picolinic acid: effect on zinc metabolism and clinical manifestations of pellagra. ( Krieger, I; Statter, M, 1987) |
| "Insulin sensitivity was negatively correlated to soleus and tibialis muscle intramyocellular lipids and intrahepatic lipid content." | 2.75 | Characterization of the metabolic and physiologic response to chromium supplementation in subjects with type 2 diabetes mellitus. ( Anderson, RA; Cefalu, WT; Levitan, L; Martin, CK; Martin, JM; Newcomer, B; Pinsonat, P; Qin, J; Rood, J; Sereda, O; Wang, ZQ; Zhang, XH, 2010) |
| " The CrPic supplementation consisted of a 500 ug dosage taken once per day." | 2.70 | The effect of chromium picolinate on muscular strength and body composition in women athletes. ( Adams, GM; Laguna, PL; Livolsi, JM, 2001) |
| "Body weight was measured as BMI and body composition after calculation from skinfold thickness." | 2.68 | [Effect of chromium yeast and chromium picolinate on body composition of obese, non-diabetic patients during and after a formula diet]. ( Bahadori, B; Schneider, H; Toplak, H; Wallner, S; Wascher, TC, 1997) |
| "Picolinic acid (PiA) is an endogenous metabolite of tryptophan that has been reported to possess a wide range of physiological actions." | 1.40 | Large amounts of picolinic acid are lethal but small amounts increase the conversion of tryptophan-nicotinamide in rats. ( Fukuwatari, T; Shibata, K, 2014) |
| "Hallmark features of type 2 diabetes mellitus include glucosuria and polyuria." | 1.38 | Renal distal tubule proliferation and increased aquaporin 2 level but decreased urine osmolality in db/db mouse: treatment with chromium picolinate. ( Abdelsayed, R; Baban, B; Liu, JY; Mozaffari, MS; Zakhary, I, 2012) |
| "These data demonstrate a lack of toxicity of trivalent Cr, at levels that are on a per kg basis, several thousand times the upper limit of the estimated safe and adequate daily dietary intake for humans." | 1.30 | Lack of toxicity of chromium chloride and chromium picolinate in rats. ( Anderson, RA; Bryden, NA; Polansky, MM, 1997) |
| " But the higher bioavailability of zinc in human milk should not only be attributed to the presence of citrate." | 1.27 | [Effect of different concentrations of various zinc complexes (picolinate, citrate, 8-hydroxyquinolate) in comparison with sulfate on zinc supply status in rats]. ( Kirchgessner, M; Roth, HP, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (13.89) | 18.7374 |
| 1990's | 4 (11.11) | 18.2507 |
| 2000's | 14 (38.89) | 29.6817 |
| 2010's | 12 (33.33) | 24.3611 |
| 2020's | 1 (2.78) | 2.80 |
| Authors | Studies |
|---|---|
| Pala, R | 1 |
| Sari, MA | 1 |
| Erten, F | 1 |
| Er, B | 1 |
| Tuzcu, M | 3 |
| Orhan, C | 2 |
| Deeh, PBD | 1 |
| Sahin, N | 3 |
| Cinar, V | 1 |
| Komorowski, JR | 3 |
| Sahin, K | 5 |
| Cicero, AF | 1 |
| Tartagni, E | 1 |
| Ertek, S | 1 |
| Brownley, KA | 1 |
| Von Holle, A | 1 |
| Hamer, RM | 1 |
| La Via, M | 1 |
| Bulik, CM | 1 |
| Biswas, A | 1 |
| Divya, S | 1 |
| Mandal, AB | 1 |
| Majumdar, S | 1 |
| Singh, R | 1 |
| Shibata, K | 1 |
| Fukuwatari, T | 1 |
| Kim, BG | 2 |
| Lindemann, MD | 2 |
| Cromwell, GL | 2 |
| Cefalu, WT | 1 |
| Rood, J | 1 |
| Pinsonat, P | 1 |
| Qin, J | 1 |
| Sereda, O | 1 |
| Levitan, L | 1 |
| Anderson, RA | 2 |
| Zhang, XH | 1 |
| Martin, JM | 1 |
| Martin, CK | 1 |
| Wang, ZQ | 1 |
| Newcomer, B | 1 |
| Aghdassi, E | 1 |
| Arendt, BM | 1 |
| Salit, IE | 1 |
| Mohammed, SS | 1 |
| Jalali, P | 1 |
| Bondar, H | 1 |
| Allard, JP | 1 |
| Moeini, MM | 1 |
| Bahrami, A | 1 |
| Ghazi, S | 1 |
| Targhibi, MR | 1 |
| Mozaffari, MS | 2 |
| Abdelsayed, R | 1 |
| Liu, JY | 1 |
| Zakhary, I | 1 |
| Baban, B | 1 |
| Ahmed, AR | 1 |
| Jha, AN | 1 |
| Davies, SJ | 1 |
| Juturu, V | 2 |
| Ulas, M | 1 |
| Kim, DS | 2 |
| Kim, TW | 2 |
| Kang, JS | 2 |
| Bernao, A | 1 |
| Meseguer, I | 1 |
| Aguilar, MV | 1 |
| Para, MC | 1 |
| Muñoz, MJ | 1 |
| Rhodes, MC | 1 |
| Hébert, CD | 1 |
| Herbert, RA | 1 |
| Morinello, EJ | 1 |
| Roycroft, JH | 1 |
| Travlos, GS | 1 |
| Abdo, KM | 1 |
| Mita, Y | 1 |
| Ishihara, K | 1 |
| Fukuchi, Y | 1 |
| Fukuya, Y | 1 |
| Yasumoto, K | 1 |
| Patel, C | 1 |
| Ballas, C | 1 |
| Schaffer, SW | 1 |
| Machaliński, B | 1 |
| Walczak, M | 1 |
| Syrenicz, A | 1 |
| Machalińska, A | 1 |
| Grymuła, K | 1 |
| Stecewicz, I | 1 |
| Wiszniewska, B | 1 |
| Dabkowska, E | 1 |
| Hockney, RA | 1 |
| Montgomery, P | 1 |
| Williams, C | 1 |
| Geddes, JR | 1 |
| Cowen, PJ | 1 |
| Proctor, SD | 1 |
| Kelly, SE | 1 |
| Stanhope, KL | 1 |
| Havel, PJ | 1 |
| Russell, JC | 1 |
| Lukaski, HC | 1 |
| Siders, WA | 1 |
| Penland, JG | 1 |
| Onderci, M | 2 |
| Ustundag, B | 1 |
| Cikim, G | 2 |
| Ozercan, IH | 1 |
| Sriramoju, V | 1 |
| Roth, HP | 2 |
| Kirchgessner, M | 2 |
| van Winkle, LJ | 1 |
| Doman, DR | 1 |
| Campione, AL | 1 |
| Wise, A | 1 |
| Gilburt, DJ | 1 |
| Myers, MJ | 2 |
| Farrell, DE | 2 |
| Evock-Clover, CM | 2 |
| Cope, CV | 1 |
| Henderson, M | 1 |
| Steele, NC | 2 |
| Bryden, NA | 1 |
| Polansky, MM | 1 |
| McDonald, MW | 1 |
| Bahadori, B | 1 |
| Wallner, S | 1 |
| Schneider, H | 1 |
| Wascher, TC | 1 |
| Toplak, H | 1 |
| Küçük, O | 1 |
| Livolsi, JM | 1 |
| Adams, GM | 1 |
| Laguna, PL | 1 |
| Park, IK | 1 |
| Om, AS | 1 |
| Ozbey, O | 1 |
| Aysondu, MH | 1 |
| Krieger, I | 1 |
| Statter, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Chromium Picolinate in Binge Eating Disorder: A Feasibility Study[NCT00904306] | Phase 1/Phase 2 | 26 participants (Actual) | Interventional | 2008-07-31 | Completed | ||
| Chromium and Insulin Action[NCT00398853] | Phase 4 | 100 participants (Actual) | Interventional | 2003-10-31 | Completed | ||
| The Effects of Chromium Supplementation on Glucose and Lipid Metabolism in Patients With HIV Infection[NCT00152893] | Phase 2 | 52 participants (Actual) | Interventional | 2002-08-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for picolinic acid and Body Weight
| Article | Year |
|---|---|
Nutraceuticals for metabolic syndrome management: from laboratory to benchside.
Topics: Animals; Berberine; Body Weight; Cardiovascular Diseases; Cinnamomum zeylanicum; Dietary Supplements | 2014 |
8 trials available for picolinic acid and Body Weight
| Article | Year |
|---|---|
A double-blind, randomized pilot trial of chromium picolinate for binge eating disorder: results of the Binge Eating and Chromium (BEACh) study.
Topics: Adult; Binge-Eating Disorder; Body Mass Index; Body Weight; Double-Blind Method; Female; Humans; Iro | 2013 |
Effects of dietary supplementation of organic chromium (picolinate) on physical and biochemical characteristics of semen and carcass traits of male turkeys.
Topics: Animal Feed; Animals; Biomarkers; Body Constitution; Body Weight; Chromium; Dietary Supplements; Fer | 2014 |
Characterization of the metabolic and physiologic response to chromium supplementation in subjects with type 2 diabetes mellitus.
Topics: Adult; Aged; Blood Glucose; Body Composition; Body Weight; Cohort Studies; Diabetes Mellitus, Type 2 | 2010 |
In patients with HIV-infection, chromium supplementation improves insulin resistance and other metabolic abnormalities: a randomized, double-blind, placebo controlled trial.
Topics: Blood Chemical Analysis; Body Composition; Body Weight; Diet; Dietary Supplements; Female; HIV; HIV | 2010 |
Lack of effect of chromium supplementation on mental state and body weight in people with schizophrenia.
Topics: Adult; Affect; Aged; Antipsychotic Agents; Body Weight; Dietary Supplements; Double-Blind Method; Fe | 2006 |
Chromium picolinate supplementation in women: effects on body weight, composition, and iron status.
Topics: Absorptiometry, Photon; Adult; Anthropometry; Biomarkers; Body Composition; Body Weight; Chromium; D | 2007 |
[Effect of chromium yeast and chromium picolinate on body composition of obese, non-diabetic patients during and after a formula diet].
Topics: Adult; Body Composition; Body Mass Index; Body Weight; Chromium; Diet, Reducing; Double-Blind Method | 1997 |
The effect of chromium picolinate on muscular strength and body composition in women athletes.
Topics: Adolescent; Adult; Baseball; Body Composition; Body Weight; Dietary Supplements; Female; Humans; Iro | 2001 |
27 other studies available for picolinic acid and Body Weight
| Article | Year |
|---|---|
The effects of chromium picolinate on glucose and lipid metabolism in running rats.
Topics: Animals; Body Weight; Feeding Behavior; Gene Expression Regulation; Glucose; Glucose Transporter Typ | 2020 |
Large amounts of picolinic acid are lethal but small amounts increase the conversion of tryptophan-nicotinamide in rats.
Topics: Animals; Body Weight; Carboxy-Lyases; Dose-Response Relationship, Drug; Iron Chelating Agents; Kynur | 2014 |
Effects of dietary chromium (III) picolinate on growth performance, respiratory rate, plasma variables, and carcass traits of pigs fed high-fat diets.
Topics: Animal Feed; Animals; Body Composition; Body Weight; Dietary Fats; Dietary Supplements; Female; Male | 2010 |
The effects of dietary chromium(III) picolinate on growth performance, vital signs, and blood measurements of pigs during immune stress.
Topics: Animal Nutritional Physiological Phenomena; Animals; Blood Glucose; Body Temperature; Body Weight; C | 2010 |
The effect of different levels of organic and inorganic chromium supplementation on production performance, carcass traits and some blood parameters of broiler chicken under heat stress condition.
Topics: Animal Feed; Animals; Body Composition; Body Weight; Chickens; Chlorides; Cholesterol; Cholesterol, | 2011 |
Renal distal tubule proliferation and increased aquaporin 2 level but decreased urine osmolality in db/db mouse: treatment with chromium picolinate.
Topics: Animals; Aquaporin 2; Biological Transport; Blood Glucose; Body Weight; Cell Proliferation; Dehydrat | 2012 |
The efficacy of chromium as a growth enhancer for mirror carp (Cyprinus carpio L): an integrated study using biochemical, genetic, and histological responses.
Topics: Animal Husbandry; Animals; Blood Glucose; Body Weight; Carps; Chlorides; Chromium Compounds; Comet A | 2012 |
Chromium picolinate modulates serotonergic properties and carbohydrate metabolism in a rat model of diabetes.
Topics: Animals; Body Weight; Brain; Carbohydrate Metabolism; Chromium; Diabetes Mellitus, Experimental; Die | 2012 |
Chromium picolinate supplementation improves insulin sensitivity in Goto-Kakizaki diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Dietary Supplements; Glucose T | 2004 |
Effect of different doses of chromium picolinate on protein metabolism in infant rats.
Topics: Animals; Animals, Newborn; Body Weight; Cathepsin A; Dietary Proteins; Dietary Supplements; Insulin; | 2004 |
Absence of toxic effects in F344/N rats and B6C3F1 mice following subchronic administration of chromium picolinate monohydrate.
Topics: Administration, Oral; Animals; Body Composition; Body Weight; Dose-Response Relationship, Drug; Eati | 2005 |
Supplementation with chromium picolinate recovers renal Cr concentration and improves carbohydrate metabolism and renal function in type 2 diabetic mice.
Topics: Animals; Blood Glucose; Body Weight; Carbohydrate Metabolism; Chromium; Creatinine; Diabetes Mellitu | 2005 |
Effects of chronic chromium picolinate treatment in uninephrectomized rat.
Topics: Animals; Body Weight; Diabetes Mellitus, Type 2; Glucose Intolerance; Insulin; Iron Chelating Agents | 2005 |
Hypoglycemic potency of novel trivalent chromium in hyperglycemic insulin-deficient rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Glucose; Body Weight; Cell Line; C | 2006 |
Synergistic effects of conjugated linoleic acid and chromium picolinate improve vascular function and renal pathophysiology in the insulin-resistant JCR:LA-cp rat.
Topics: Adiponectin; Albuminuria; Animals; Aorta; Body Weight; Diabetic Nephropathies; Dose-Response Relatio | 2007 |
Effect of chromium on carbohydrate and lipid metabolism in a rat model of type 2 diabetes mellitus: the fat-fed, streptozotocin-treated rat.
Topics: Animals; Biomarkers; Body Weight; Carbohydrate Metabolism; Diabetes Mellitus, Experimental; Diet, At | 2007 |
[Effect of different concentrations of various zinc complexes (picolinate, citrate, 8-hydroxyquinolate) in comparison with sulfate on zinc supply status in rats].
Topics: Alkaline Phosphatase; Animals; Body Weight; Citrates; Citric Acid; Diet; Hydroxyquinolines; Male; Ox | 1983 |
Effects of dietary picolinate on mice deprived of tryptophan, niacin and vitamin B-6.
Topics: Animals; Blastocyst; Body Weight; Diet; Female; Mice; Niacin; Picolinic Acids; Pregnancy; Tryptophan | 1983 |
In vitro competition between calcium phytate and the soluble fraction of rat small intestine contents for cadmium, copper and zinc.
Topics: Amino Acids; Animals; Binding, Competitive; Body Weight; Cadmium; Copper; In Vitro Techniques; Intes | 1982 |
Effect of recombinant growth hormone and chromium picolinate on cytokine production and growth performance in swine.
Topics: Animals; Body Composition; Body Weight; Cytokines; Diet; Growth Hormone; Iron Chelating Agents; Pico | 1995 |
Lack of toxicity of chromium chloride and chromium picolinate in rats.
Topics: Animals; Blood Glucose; Body Weight; Chlorides; Cholesterol; Chromium Compounds; Diet; Iron Chelatin | 1997 |
Effect of growth hormone or chromium picolinate on swine metabolism and inflammatory cytokine production after endotoxin challenge exposure.
Topics: Analysis of Variance; Animals; Aspartate Aminotransferases; Bilirubin; Blood Glucose; Blood Urea Nit | 1997 |
Effects of dietary chromium picolinate supplementation on performance and plasma concentrations of insulin and corticosterone in laying hens under low ambient temperature.
Topics: Animals; Body Weight; Chickens; Corticosterone; Dietary Supplements; Dose-Response Relationship, Dru | 2001 |
Effects of chromium picolinate supplementation on insulin sensitivity, serum lipids, and body weight in dexamethasone-treated rats.
Topics: Animals; Blood Glucose; Body Weight; Cholesterol; Dexamethasone; Dietary Supplements; Glucocorticoid | 2002 |
Chromium supplementation can alleviate negative effects of heat stress on egg production, egg quality and some serum metabolites of laying Japanese quail.
Topics: Animals; Blood Glucose; Body Weight; Corticosterone; Coturnix; Dietary Supplements; Dose-Response Re | 2002 |
Tryptophan deficiency and picolinic acid: effect on zinc metabolism and clinical manifestations of pellagra.
Topics: Animals; Body Weight; Bone and Bones; Diet; Male; Pellagra; Picolinic Acids; Rats; Rats, Inbred Stra | 1987 |
Utilization of zinc from picolinic or citric acid complexes in relation to dietary protein source in rats.
Topics: Animals; Body Weight; Caseins; Citrates; Citric Acid; Dietary Proteins; Femur; Male; Milk Proteins; | 1985 |