picolinic acid has been researched along with Aging in 4 studies
picolinic acid: iron-chelating agent that inhibits DNA synthesis; may interfere with iron-dependent production of stable free organic radical which is essential for ribonucleotide reductase formation of deoxyribonucleotides; RN given refers to parent cpd; structure in Merck Index, 9th ed, #7206
picolinic acid : A pyridinemonocarboxylic acid in which the carboxy group is located at position 2. It is an intermediate in the metabolism of tryptophan.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The kynurenine pathway of tryptophan catabolism plays an important role in several biological systems affected by aging." | 3.77 | Changes in kynurenine pathway metabolism in the brain, liver and kidney of aged female Wistar rats. ( Braidy, N; Chan-Ling, T; Grant, R; Guillemin, GJ; Mansour, H, 2011) |
| "In patients with no apparent CNS disease, CSF PIC levels were 10-fold higher in samples taken between 20:00 and 16:00 h compared with those collected between 04:00 and 12:00 h." | 1.35 | Age and circadian influences on picolinic acid concentrations in human cerebrospinal fluid. ( Bilgin, A; Coggan, SE; Grant, RS; Smythe, GA, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Coggan, SE | 1 |
| Smythe, GA | 1 |
| Bilgin, A | 1 |
| Grant, RS | 1 |
| Braidy, N | 1 |
| Guillemin, GJ | 1 |
| Mansour, H | 1 |
| Chan-Ling, T | 1 |
| Grant, R | 1 |
| McCarty, MF | 2 |
4 other studies available for picolinic acid and Aging
| Article | Year |
|---|---|
Age and circadian influences on picolinic acid concentrations in human cerebrospinal fluid.
Topics: Aging; Analysis of Variance; C-Reactive Protein; Case-Control Studies; Central Nervous System Diseas | 2009 |
Changes in kynurenine pathway metabolism in the brain, liver and kidney of aged female Wistar rats.
Topics: Aging; Animals; Brain; Chromatography, High Pressure Liquid; Female; Gas Chromatography-Mass Spectro | 2011 |
Longevity effect of chromium picolinate--'rejuvenation' of hypothalamic function?
Topics: Aging; Animals; Humans; Hypothalamus; Insulin; Phenformin; Picolinic Acids; Rats; Rejuvenation | 1994 |
Homologous physiological effects of phenformin and chromium picolinate.
Topics: Adipose Tissue; Aging; Animals; Brain; Humans; Insulin Resistance; Longevity; Neoplasms, Experimenta | 1993 |