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picolinic acid and Aggression

picolinic acid has been researched along with Aggression in 1 studies

picolinic acid: iron-chelating agent that inhibits DNA synthesis; may interfere with iron-dependent production of stable free organic radical which is essential for ribonucleotide reductase formation of deoxyribonucleotides; RN given refers to parent cpd; structure in Merck Index, 9th ed, #7206
picolinic acid : A pyridinemonocarboxylic acid in which the carboxy group is located at position 2. It is an intermediate in the metabolism of tryptophan.

Aggression: Behavior which may be manifested by destructive and attacking action which is verbal or physical, by covert attitudes of hostility or by obstructionism.

Research Excerpts

ExcerptRelevanceReference
"Inflammatory proteins are thought to be causally involved in the generation of aggression, possibly due to direct effects of cytokines in the central nervous system and/or by generation of inflammatory metabolites along the tryptophan-kynurenine (TRP/KYN) pathway, including KYN and its active metabolites kynurenic acid (KA), quinolinic acid (QA), and picolinic acid (PA)."7.83Tryptophan, kynurenine, and kynurenine metabolites: Relationship to lifetime aggression and inflammatory markers in human subjects. ( Brundin, L; Christensen, K; Coccaro, EF; Coussons-Read, M; Erhardt, S; Fanning, JR; Fuchs, D; Goiny, M; Lee, R, 2016)
"Inflammatory proteins are thought to be causally involved in the generation of aggression, possibly due to direct effects of cytokines in the central nervous system and/or by generation of inflammatory metabolites along the tryptophan-kynurenine (TRP/KYN) pathway, including KYN and its active metabolites kynurenic acid (KA), quinolinic acid (QA), and picolinic acid (PA)."3.83Tryptophan, kynurenine, and kynurenine metabolites: Relationship to lifetime aggression and inflammatory markers in human subjects. ( Brundin, L; Christensen, K; Coccaro, EF; Coussons-Read, M; Erhardt, S; Fanning, JR; Fuchs, D; Goiny, M; Lee, R, 2016)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Coccaro, EF1
Lee, R1
Fanning, JR1
Fuchs, D1
Goiny, M1
Erhardt, S1
Christensen, K1
Brundin, L1
Coussons-Read, M1

Other Studies

1 other study available for picolinic acid and Aggression

ArticleYear
Tryptophan, kynurenine, and kynurenine metabolites: Relationship to lifetime aggression and inflammatory markers in human subjects.
    Psychoneuroendocrinology, 2016, Volume: 71

    Topics: Adult; Aggression; Biomarkers; C-Reactive Protein; Female; Humans; Inflammation; Interleukin-6; Kynu

2016