Page last updated: 2024-10-20

picolinic acid and Adult Refsum Disease

picolinic acid has been researched along with Adult Refsum Disease in 1 studies

picolinic acid: iron-chelating agent that inhibits DNA synthesis; may interfere with iron-dependent production of stable free organic radical which is essential for ribonucleotide reductase formation of deoxyribonucleotides; RN given refers to parent cpd; structure in Merck Index, 9th ed, #7206
picolinic acid : A pyridinemonocarboxylic acid in which the carboxy group is located at position 2. It is an intermediate in the metabolism of tryptophan.

Research Excerpts

ExcerptRelevanceReference
"Refsum's disease is a complex and difficult to diagnose storage disease caused by complex autosomal recessive peroxisomal disorder in which mutations of phytanolyl/pristanoyl-CoA-hydroxilase are the main cause."1.32Membrane differential filtration is safe and effective for the long-term treatment of Refsum syndrome--an update of treatment modalities and pathophysiological cognition. ( Gäckler, D; Kingreen, H; Klingel, R; Muselmann, L; Straube, R; Thiele, A, 2003)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Straube, R1
Gäckler, D1
Thiele, A1
Muselmann, L1
Kingreen, H1
Klingel, R1

Other Studies

1 other study available for picolinic acid and Adult Refsum Disease

ArticleYear
Membrane differential filtration is safe and effective for the long-term treatment of Refsum syndrome--an update of treatment modalities and pathophysiological cognition.
    Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis, 2003, Volume: 29, Issue:1

    Topics: Blood Component Removal; Diseases in Twins; Fatty Acids; Female; Filtration; Humans; Lipid Metabolis

2003