Compounds > picolinamide
Page last updated: 2024-08-21

picolinamide and Alloxan Diabetes

picolinamide has been researched along with Alloxan Diabetes in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Han, HY; Kim, JS; Kim, S; Lee, HJ; Park, HG; Ryu, JH; Shin, YA; Son, HJ1
Han, HY; Kim, JS; Kim, S; Kim, YH; Lee, HJ; Lee, JA; Park, HG; Ryu, JH; Son, HJ1
Okamoto, H; Yamamoto, H1

Other Studies

3 other study(ies) available for picolinamide and Alloxan Diabetes

ArticleYear
Synthesis and biological evaluation of picolinamides as potent inhibitors of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1).
    Bioorganic & medicinal chemistry letters, 2015, Feb-01, Volume: 25, Issue:3

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Amides; Animals; Binding Sites; Blood Glucose; Cell Survival; Diabetes Mellitus, Experimental; Disease Models, Animal; Enzyme Inhibitors; HEK293 Cells; Humans; Male; Mice; Mice, Inbred C57BL; Molecular Dynamics Simulation; Picolinic Acids; Protein Structure, Tertiary; Structure-Activity Relationship

2015
Synthesis and optimization of picolinamide derivatives as a novel class of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors.
    Bioorganic & medicinal chemistry letters, 2015, Apr-15, Volume: 25, Issue:8

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Administration, Oral; Amides; Animals; Blood Glucose; Catalysis; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Half-Life; HEK293 Cells; Humans; Lipids; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Palladium; Picolinic Acids; Protein Binding; Structure-Activity Relationship

2015
Protection by picolinamide, a novel inhibitor of poly (ADP-ribose) synthetase, against both streptozotocin-induced depression of proinsulin synthesis and reduction of NAD content in pancreatic islets.
    Biochemical and biophysical research communications, 1980, Jul-16, Volume: 95, Issue:1

    Topics: Amides; Animals; Cell Nucleus; Diabetes Mellitus, Experimental; Islets of Langerhans; Male; NAD; NAD+ Nucleosidase; Niacinamide; Picolinic Acids; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Proinsulin; Rats; Streptozocin

1980