picibanil has been researched along with Urogenital-Neoplasms* in 4 studies
4 other study(ies) available for picibanil and Urogenital-Neoplasms
| Article | Year |
|---|---|
[Changes in ASP (antigroup-A streptococcal C polysaccharide antibody) and cardiac and renal effects in cases of urogenital cancers during OK-432 immunotherapy, streptococcus preparation].
Topics: Adult; Aged; Antibodies, Bacterial; Antibody Formation; Biological Products; Female; Humans; Immunotherapy; Kidney; Male; Middle Aged; Myocardium; Picibanil; Polysaccharides, Bacterial; Urogenital Neoplasms | 1988 |
[Studies of immunotherapy of malignant urogenital tumors: 2nd report. Changes in the K-cell population of the peripheral blood in patients with malignant tumors and the significance of antibody dependent cell-mediated cytotoxicity (ADCC) in OK-432 immunot
Topics: Adult; Aged; Antibody-Dependent Cell Cytotoxicity; Biological Products; Female; Humans; Killer Cells, Natural; Leukocyte Count; Male; Middle Aged; Picibanil; Urogenital Neoplasms | 1987 |
Effect of streptococcal preparation (picibanil) on the postoperative rise in serum alanine aminotransferase activity in patients with urogenital cancer.
The effect of Picibanil, a streptococcal agent, on the development of liver injury after operations for urogenital cancer was studied retrospectively in the light of serum alanine aminotransferase (ALT) activity. The series comprised 32 cases receiving Picibanil and 33 controls with otherwise comparable clinical backgrounds. Picibanil reduced the incidence of postoperative ALT rise over 50 U/l within 6 weeks but increased it thereafter. The increase in ALT activity after 6 weeks was relatively small and was seen more often in patients given blood transfusions. It was interpreted as retardation and suppression of ALT rise and as being related to the induction of interferon or to immunopotentiation. Other antihepatotoxic effects of Picibanil, due to its antioxidant activity, for example, may also account for the prevention of the early postoperative rise in ALT activity. Topics: Adult; Aged; Alanine Transaminase; Biological Products; Female; Humans; Liver Diseases; Male; Middle Aged; Picibanil; Postoperative Period; Urogenital Neoplasms | 1980 |
Adjuvant immunotherapy with a S. pyogenes preparation (OK432) in urogenital cancer patients.
We evaluated the immunostimulative activity of a Streptococcus pyogenes preparation (OK432) in 50 patients with urogenital carcinoma. Differential lymphocyte blastogenic response to mitogens and quantitation of the lymphocyte subpopulation bearing Fc receptor sites were the two immunoparameters used in this study to assess the status of the cancer-bearing host. Using these immunoparameters, we observed a pattern whereby a substantial deviation from unity in the mitogen reactive ratio and an increase in the number of IgGFcR+T cells were correlated with malignant progression; administration of the immunopotentiator OK432 had a marked effect on immunoparameters reflected by our assays, with a trend toward return to normal values with progression of immunotherapy. Topics: Adult; Aged; Biological Products; Doxorubicin; Female; Humans; Lymphocyte Activation; Male; Middle Aged; Picibanil; Receptors, Fc; T-Lymphocytes; Urinary Bladder Neoplasms; Urogenital Neoplasms | 1980 |