pica and Celiac-Disease

Topics: Anemia, Iron-Deficiency; Celiac Disease; Child; Diagnosis, Differential; Female; Humans; Pica

Topics: Abdomen; Anemia, Iron-Deficiency; Celiac Disease; Child, Preschool; Female; Foreign Bodies; Humans; Lactulose; Pica; Radiography

Pica is defined as developmentally inappropriate consumption of nonnutritive substances for at least 1 month. There are a few studies on serum trace element levels of patients with pica. The literature contains contracting data on the levels of oxidative stress and antioxidant levels in patients with iron-deficiency anemia (IDA). The effect of pica on oxidative stress and antioxidant capacity has not been investigated yet. The present study evaluated the effects of pica and IDA on oxidative stress and antioxidant capacity as well as on the levels of trace elements including serum zinc and selenium in 47 children with IDA plus pica, 22 children with IDA only and 21 nonanemic children as controls. The results demonstrated significantly lower levels of serum selenium and zinc in pica and IDA groups compared to the control group. Total oxidant levels were highest in the pica group and consistently, the lowest total antioxidant capacity was observed again in the pica group. Comparison of pica and IDA groups yielded significantly lower levels of total antioxidant levels and significantly higher oxidative stress index in the pica group. Consequently, it is thought that the detrimental effects of pica within the organism were mediated by adverse impacts on antioxidant capacity and oxidative stress. These effects should be kept in mind while managing patients with pica.

Topics: Adolescent; Anemia, Iron-Deficiency; Antioxidants; Case-Control Studies; Celiac Disease; Child; Child, Preschool; Duodenum; Gastroscopy; Humans; Infant; Oxidative Stress; Pica; Selenium; Trace Elements; Zinc

Topics: Anemia, Iron-Deficiency; Calcium Sulfate; Celiac Disease; Humans; Male; Pica; Young Adult

Topics: Anemia, Iron-Deficiency; Celiac Disease; Child; Diagnostic Errors; Glutens; Humans; Male; Obsessive-Compulsive Disorder; Pica

Association of pica, iron deficiency anaemia (IDA) and celiac disease (CD) have been reported in the literature. An unusual but completely reversible form of pica in the form obsessive compulsive sponge eating (pervasive disorder) was reported as an odd manifestation of IDA and CD.. The medical practice is full of challenges and complexity; and clinicians need to be vigilant all the time in their practice to appreciate unusual and rare manifestations of common clinical conditions like IDA and CD.

Topics: Anemia, Iron-Deficiency; Celiac Disease; Child; Child, Preschool; Diagnosis, Differential; Female; Humans; Iron; Male; Obsessive-Compulsive Disorder; Pica

We report on a case of childhood coeliac disease presenting with tricophagia and trichobezoar. The combination of obstructive symptoms, severe hypoalbuminaemia and a large abdominal mass detected on CT scan warranted diagnostic gastroscopy and laparotomy, resulting in removal of a large gastric trichobezoar. Surgical recovery was uneventful although serologic studies for coeliac disease were abnormal. Coeliac disease was confirmed by subsequent biopsy.. Concomitant trichobezoar and coeliac disease in a child is reported for the first time. It is postulated that the trichobezoar was a result of coeliac disease-induced pica.

Topics: Bezoars; Celiac Disease; Child; Digestive System Surgical Procedures; Female; Humans; Laparotomy; Pica

Topics: Albendazole; Anemia, Iron-Deficiency; Animals; Anthelmintics; Antibodies, Helminth; Celiac Disease; Child, Preschool; Female; Humans; Iron; Liver Diseases, Parasitic; Lung Diseases, Parasitic; Pica; Risk Factors; Tomography, X-Ray Computed; Toxocara canis; Toxocariasis; Ultrasonography

Topics: Adult; Anemia, Iron-Deficiency; Celiac Disease; Female; Humans; Pica

Topics: Celiac Disease; Child, Preschool; Female; Humans; Pica

Persistent pica may be either a cause or a result of iron deficiency. Three children are described with long-standing pica and iron-deficiency anemia and in whom total villous atrophy consistent with celiac disease was found on jejunal biopsy. Additional findings included short stature, delayed bone age, and impaired xylose absorption. A dramatic growth spurt and complete resolution of pica were observed after a gluten-free diet. In these cases pica evidently resulted from iron deficiency secondary to malabsorption. Underlying celiac disease should be considered in children with persistent pica and growth failure even if gastrointestinal disturbances are minimal.

Topics: Anemia, Hypochromic; Celiac Disease; Child, Preschool; Female; Glutens; Humans; Male; Pica

Topics: Adult; Brain Diseases; Celiac Disease; Female; Humans; Lead Poisoning; Menopause; Pica; Time Factors