pi103 and Lymphoma--B-Cell

pi103 has been researched along with Lymphoma--B-Cell* in 1 studies

Other Studies

1 other study(ies) available for pi103 and Lymphoma--B-Cell

ArticleYear
Design, synthesis and biological evaluation of novel benzothiadiazine derivatives as potent PI3Kδ-selective inhibitors for treating B-cell-mediated malignancies.
    European journal of medicinal chemistry, 2019, May-15, Volume: 170

    A series of 24 benzothiadiazine derivatives with structural novelty were designed, synthesized and biologically evaluated as PI3Kδ-selective inhibitors. As a consequence of the structure-activity relationship (SAR) study, compounds 63 and 71 were identified with single-digit nanomolar IC

    Topics: Administration, Oral; Animals; Antineoplastic Agents; B-Lymphocytes; Benzothiadiazines; Cell Line, Tumor; Cell Proliferation; Class I Phosphatidylinositol 3-Kinases; Drug Design; Lymphoma, B-Cell; Molecular Docking Simulation; Protein Kinase Inhibitors; Rats, Sprague-Dawley

2019