pi103 has been researched along with Arrhythmias--Cardiac* in 1 studies
1 other study(ies) available for pi103 and Arrhythmias--Cardiac
Article | Year |
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Modulating the voltage sensor of a cardiac potassium channel shows antiarrhythmic effects.
Cardiac arrhythmias are the most common cause of sudden cardiac death worldwide. Lengthening the ventricular action potential duration (APD), either congenitally or via pathologic or pharmacologic means, predisposes to a life-threatening ventricular arrhythmia, Torsade de Pointes. I Topics: Action Potentials; Amino Acid Substitution; Animals; Arrhythmias, Cardiac; Calcium; Dogs; Furans; Gene Expression; Guinea Pigs; Heart Atria; Heart Ventricles; Humans; KCNQ1 Potassium Channel; Moxifloxacin; Myocytes, Cardiac; Oocytes; Patch-Clamp Techniques; Phenethylamines; Potassium; Primary Cell Culture; Pyridines; Pyrimidines; Small Molecule Libraries; Sodium; Sulfonamides; Transgenes; Xenopus laevis | 2021 |