phytoestrogens and Malnutrition

There is a growing interest in diets and their effects on cancer prognosis. In 2014, a report from the World Cancer Research Fund on diet and women with a history of breast cancer did not demonstrate a major effect on breast cancer prognosis. The aim of this literature review was to provide an update of knowledge in this area.. Randomized trials, prospective cohorts and meta-analyses published between 2012 and 2018 examining the impact of diet on recurrence risk and/or mortality after breast cancer were included, to achieve the objective. We evaluated study quality (according to Haute Autorité de Santé criteria) and the studied diets were categorized: macronutrients, micronutrients and selective foods.. We selected eighteen articles that met levels of evidence 1 to 3. For macronutrients, a low-fat diet was associated with better survival. With regard to micronutrients, a diet rich in phytœstrogen reduced the risk of cancer recurrence. Finally, the adoption of a healthy diet was not associated with an improved prognosis for breast cancer but with an improvement in overall survival and risk of death from cardiovascular disease.. This review suggests that nutrition influences the prognosis of breast cancer. Nevertheless, the level of evidence of the results was insufficient to make recommendations. Ultimately, a healthy and balanced diet could be encouraged in order to reduce global mortality.

Topics: Breast Neoplasms; Cardiovascular Diseases; Cooking; Diet, Fat-Restricted; Diet, Healthy; Evidence-Based Medicine; Fasting; Female; Food; Humans; Inflammation; Malnutrition; Meta-Analysis as Topic; Micronutrients; Nutrients; Nutrition Policy; Nutritional Status; Nutritional Support; Phytoestrogens; Prognosis; Prospective Studies; Randomized Controlled Trials as Topic; Recurrence; Risk