Page last updated: 2024-10-19

phytic acid and Tooth Discoloration

phytic acid has been researched along with Tooth Discoloration in 2 studies

Phytic Acid: Complexing agent for removal of traces of heavy metal ions. It acts also as a hypocalcemic agent.
myo-inositol hexakisphosphate : A myo-inositol hexakisphosphate in which each hydroxy group of myo-inositol is monophosphorylated.

Tooth Discoloration: Any change in the hue, color, or translucency of a tooth due to any cause. Restorative filling materials, drugs (both topical and systemic), pulpal necrosis, or hemorrhage may be responsible. (Jablonski, Dictionary of Dentistry, 1992, p253)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Liu, H1
Tu, J1
Milleman, KR1
Creeth, JE1
Burnett, GR1
Milleman, JL1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy of a Commercial Dentifrice Containing 10% High Cleaning Silica Base, 0.5% Sodium Phytate and 0.5% Sodium Pyrophosphate on Tooth Whitening: A 8-week Clinical Study in Adults in China[NCT04238429]86 participants (Actual)Interventional2018-05-07Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Lobene Stain Index of Stain Area Scores 4 Weeks After Dentifrice Use

Tooth stain of the anterior teeth were measured using the Lobene Stain Index. The index measures the area and intensity of extrinsic tooth stain on the facial and lingual surfaces of the lower anterior teeth and facial surfaces of the upper anterior teeth. The tooth surfaces were divided into two parts: body and gingival. For each part, the stain area was assessed using 0-3 scale. 0= No stain detected; 1= stain covering up to 1/3 of the region; 2= Stain covering >1/3 to 2/3 of the region; 3=Stain covering >2/3 of the region. (NCT04238429)
Timeframe: 4 weeks after dentifrice use

Interventionscore on a scale (Mean)
Toothpaste Containing Effective Ingredients1.1
Negative Control Toothpaste1.32

Lobene Stain Index of Stain Area Scores 8 Weeks After Dentifrice Use

Tooth stain of the anterior teeth were measured using the Lobene Stain Index. The index measures the area and intensity of extrinsic tooth stain on the facial and lingual surfaces of the lower anterior teeth and facial surfaces of the upper anterior teeth. The tooth surfaces were divided into two parts: body and gingival. For each part, the stain area was assessed using 0-3 scale. 0= No stain detected; 1= stain covering up to 1/3 of the region; 2= Stain covering >1/3 to 2/3 of the region; 3=Stain covering >2/3 of the region. (NCT04238429)
Timeframe: 8 weeks after dentifrice use

Interventionscore on a scale (Mean)
Toothpaste Containing Effective Ingredients0.83
Negative Control Toothpaste1.12

Lobene Stain Index of Stain Composite Scores 4 Weeks After Dentifrice Use

Tooth stain of the anterior teeth were measured using the Lobene Stain Index. The tooth surfaces were divided into two parts: body and gingival. For each part, the stain area was assessed using 0-3 scale and the stain intensity was assessed using 0-3 scale. Lobene Stain Index: Composite for each part is the product of the stain area and intensity scores. The minimum score for Lobene Stain Index: Composite is 0 when both the stain area and intensity scores are 0. The maximum score for Lobene Stain Index: Composite is 9 when both the stain area and intensity scores are 3. (NCT04238429)
Timeframe: 4 weeks after dentifrice use

Interventionscore on a scale (Mean)
Toothpaste Containing Effective Ingredients2.39
Negative Control Toothpaste3.23

Lobene Stain Index of Stain Composite Scores 8 Weeks After Dentifrice Use

Tooth stain of the anterior teeth were measured using the Lobene Stain Index. The tooth surfaces were divided into two parts: body and gingival. For each part, the stain area was assessed using 0-3 scale and the stain intensity was assessed using 0-3 scale. Lobene Stain Index: Composite for each part is the product of the stain area and intensity scores. The minimum score for Lobene Stain Index: Composite is 0 when both the stain area and intensity scores are 0. The maximum score for Lobene Stain Index: Composite is 9 when both the stain area and intensity scores are 3. (NCT04238429)
Timeframe: 8 weeks after dentifrice use

Interventionscore on a scale (Mean)
Toothpaste Containing Effective Ingredients1.45
Negative Control Toothpaste2.5

Lobene Stain Index of Stain Extent Scores 4 Weeks After Dentifrice Use

Tooth stain of the anterior teeth were measured using the Lobene Stain Index. The index measures the area and intensity of extrinsic tooth stain on the facial and lingual surfaces of the lower anterior teeth and facial surfaces of the upper anterior teeth. The tooth surfaces were divided into two parts: body and gingival. For each part, the stain intensity was assessed using 0-3 scale. 0= No stain; 1=Light stain(yellow to light brown or gray); 2=Moderate stain(medium brown); 3=Heavy stain(dark brown to black). (NCT04238429)
Timeframe: 4 weeks after dentifrice use

Interventionscore on a scale (Mean)
Toothpaste Containing Effective Ingredients1.35
Negative Control Toothpaste1.64

Lobene Stain Index of Stain Extent Scores 8 Weeks After Dentifrice Use

Tooth stain of the anterior teeth were measured using the Lobene Stain Index. The index measures the area and intensity of extrinsic tooth stain on the facial and lingual surfaces of the lower anterior teeth and facial surfaces of the upper anterior teeth. The tooth surfaces were divided into two parts: body and gingival. For each part, the stain intensity was assessed using 0-3 scale. 0= No stain; 1=Light stain(yellow to light brown or gray); 2=Moderate stain(medium brown); 3=Heavy stain(dark brown to black). (NCT04238429)
Timeframe: 8 weeks after dentifrice use

Interventionscore on a scale (Mean)
Toothpaste Containing Effective Ingredients0.98
Negative Control Toothpaste1.33

Trials

2 trials available for phytic acid and Tooth Discoloration

ArticleYear
Reduction of extrinsic tooth stain by a toothpaste containing 10% high cleaning silica, 0.5% sodium phytate and 0.5% sodium pyrophosphate: an 8-week randomised clinical trial.
    BMC oral health, 2021, 03-11, Volume: 21, Issue:1

    Topics: Adult; Dentifrices; Diphosphates; Humans; Phytic Acid; Silicon Dioxide; Sodium Fluoride; Tooth Bleac

2021
A randomized clinical trial to evaluate the stain removal efficacy of a sodium phytate dentifrice formulation.
    Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.], 2018, Volume: 30, Issue:2

    Topics: Coloring Agents; Dentifrices; Double-Blind Method; Humans; Phytic Acid; Silicon Dioxide; Tooth Disco

2018