phytic acid has been researched along with Prostatic Neoplasms in 15 studies
Phytic Acid: Complexing agent for removal of traces of heavy metal ions. It acts also as a hypocalcemic agent.
myo-inositol hexakisphosphate : A myo-inositol hexakisphosphate in which each hydroxy group of myo-inositol is monophosphorylated.
Prostatic Neoplasms: Tumors or cancer of the PROSTATE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "IP6 inhibited prostate cancer progression at prostatic intraepithelial neoplasia stage and strongly reduced the incidence of adenocarcinoma (prostatic intraepithelial neoplasia/adenocarcinoma, 75:25% in the IP6 group versus 39:61% in the control group; P < 0." | 1.35 | Chemopreventive efficacy of inositol hexaphosphate against prostate tumor growth and progression in TRAMP mice. ( Agarwal, R; Raina, K; Rajamanickam, S; Singh, RP, 2008) |
| "Because few prostate cancer (PCa) cell lines have been used to study IP6, we assessed its efficacy in a panel of PCa cell lines." | 1.33 | An androgen-independent androgen receptor function protects from inositol hexakisphosphate toxicity in the PC3/PC3(AR) prostate cancer cell lines. ( Delvoye, N; Diallo, JS; Le Page, C; Lessard, L; Mes-Masson, AM; Péant, B; Saad, F, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.67) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 10 (66.67) | 29.6817 |
| 2010's | 3 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhu, HP | 1 |
| Yun, F | 1 |
| Jiu, T | 1 |
| Diallo, JS | 2 |
| Betton, B | 1 |
| Parent, N | 1 |
| Péant, B | 2 |
| Lessard, L | 2 |
| Le Page, C | 2 |
| Bertrand, R | 1 |
| Mes-Masson, AM | 2 |
| Saad, F | 2 |
| Roy, S | 2 |
| Gu, M | 3 |
| Ramasamy, K | 1 |
| Singh, RP | 6 |
| Agarwal, C | 5 |
| Siriwardana, S | 1 |
| Sclafani, RA | 1 |
| Agarwal, R | 9 |
| Raina, K | 4 |
| Ravichandran, K | 1 |
| Rajamanickam, S | 2 |
| Huber, KM | 1 |
| Serkova, NJ | 1 |
| Sharma, G | 2 |
| Mallikarjuna, GU | 1 |
| Dhanalakshmi, S | 1 |
| Delvoye, N | 1 |
| Jagadeesh, S | 1 |
| Banerjee, PP | 1 |
| Osborne, MP | 1 |
| Meijer, WS | 1 |
| Yeh, SD | 1 |
| DeCosse, JJ | 1 |
| Shamsuddin, AM | 1 |
| Yang, GY | 1 |
| Zi, X | 1 |
1 review available for phytic acid and Prostatic Neoplasms
| Article | Year |
|---|---|
Lymphoscintigraphy in the staging of solid tumors.
Topics: Antimony; Ascites; Breast Neoplasms; Colloids; Female; Gastrointestinal Neoplasms; Gold Colloid, Rad | 1983 |
14 other studies available for phytic acid and Prostatic Neoplasms
| Article | Year |
|---|---|
[Inhibitory effect of inositol hexaphosphate on proliferation of LNCaP cells and its relation to IGFBP 3 expression].
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Gene Silencing; Humans; Insulin-Like Growth Factor | 2014 |
Enhanced killing of androgen-independent prostate cancer cells using inositol hexakisphosphate in combination with proteasome inhibitors.
Topics: Androgens; Anticarcinogenic Agents; Apoptosis; Cell Line, Tumor; Humans; Male; Phytic Acid; Prostati | 2008 |
p21/Cip1 and p27/Kip1 Are essential molecular targets of inositol hexaphosphate for its antitumor efficacy against prostate cancer.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase | 2009 |
Inositol hexaphosphate downregulates both constitutive and ligand-induced mitogenic and cell survival signaling, and causes caspase-mediated apoptotic death of human prostate carcinoma PC-3 cells.
Topics: Apoptosis; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA, Neoplasm; Down-Regul | 2010 |
Inositol hexaphosphate suppresses growth and induces apoptosis in prostate carcinoma cells in culture and nude mouse xenograft: PI3K-Akt pathway as potential target.
Topics: Animals; Apoptosis; Cell Growth Processes; Cyclin D1; DNA, Neoplasm; Humans; Hypoxia-Inducible Facto | 2009 |
Inositol hexaphosphate inhibits tumor growth, vascularity, and metabolism in TRAMP mice: a multiparametric magnetic resonance study.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Biomarkers, Tumor; Body Weight; Cell Proliferatio | 2013 |
Inositol hexaphosphate inhibits growth, and induces G1 arrest and apoptotic death of prostate carcinoma DU145 cells: modulation of CDKI-CDK-cyclin and pRb-related protein-E2F complexes.
Topics: Apoptosis; Cell Cycle Proteins; Cell Division; Cyclin-Dependent Kinases; Cyclins; DNA-Binding Protei | 2003 |
Growth inhibitory and apoptotic effects of inositol hexaphosphate in transgenic adenocarcinoma of mouse prostate (TRAMP-C1) cells.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Caspase Inhibitors; Caspases; Cell Cycle; | 2003 |
In vivo suppression of hormone-refractory prostate cancer growth by inositol hexaphosphate: induction of insulin-like growth factor binding protein-3 and inhibition of vascular endothelial growth factor.
Topics: Animal Feed; Animals; Apoptosis; Body Weight; Enzyme-Linked Immunosorbent Assay; Humans; Immunoenzym | 2004 |
An androgen-independent androgen receptor function protects from inositol hexakisphosphate toxicity in the PC3/PC3(AR) prostate cancer cell lines.
Topics: Androgens; Apoptosis; Caspase 3; Caspases; Cell Line, Tumor; DNA Fragmentation; DNA, Neoplasm; Drug | 2006 |
Inositol hexaphosphate represses telomerase activity and translocates TERT from the nucleus in mouse and human prostate cancer cells via the deactivation of Akt and PKCalpha.
Topics: Animals; Cell Line, Tumor; Cell Nucleus; Dose-Response Relationship, Drug; Down-Regulation; Enzyme A | 2006 |
Chemopreventive efficacy of inositol hexaphosphate against prostate tumor growth and progression in TRAMP mice.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Cell Proliferation; Immunohistochemistry; | 2008 |
Inositol hexaphosphate inhibits growth and induces differentiation of PC-3 human prostate cancer cells.
Topics: Acid Phosphatase; Cell Differentiation; Cell Division; DNA; Histocompatibility Antigens Class I; Hum | 1995 |
Impairment of erbB1 receptor and fluid-phase endocytosis and associated mitogenic signaling by inositol hexaphosphate in human prostate carcinoma DU145 cells.
Topics: Adaptor Protein Complex 2; Adaptor Protein Complex alpha Subunits; Adaptor Proteins, Vesicular Trans | 2000 |