phytic acid has been researched along with HbS Disease in 8 studies
Phytic Acid: Complexing agent for removal of traces of heavy metal ions. It acts also as a hypocalcemic agent.
myo-inositol hexakisphosphate : A myo-inositol hexakisphosphate in which each hydroxy group of myo-inositol is monophosphorylated.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The cystamine-treated cells demonstrated a marked inhibition of sickling under hypoxic conditions, a decrease in their mean corpuscular hemoglobin concentration, and a significant increase in their oxygen affinity." | 1.26 | Inhibition of erythrocyte sickling by cystamine, a thiol reagent. ( Beuzard, Y; Hassan, W; Rosa, J, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bourgeaux, V | 3 |
| Hequet, O | 1 |
| Campion, Y | 3 |
| Delcambre, G | 1 |
| Chevrier, AM | 2 |
| Rigal, D | 1 |
| Godfrin, Y | 3 |
| Aufradet, E | 1 |
| De Souza, G | 1 |
| Horand, F | 1 |
| Bessaad, A | 1 |
| Canet-Soulas, E | 1 |
| Martin, C | 2 |
| Lamarre, Y | 1 |
| Pichon, A | 1 |
| Hardeman, MR | 1 |
| Hardeman-Zijp, M | 1 |
| Richalet, JP | 1 |
| Bernaudin, F | 1 |
| Driss, F | 1 |
| Connes, P | 1 |
| Kumpati, J | 1 |
| Franco, RS | 2 |
| Weiner, M | 2 |
| Martelo, OJ | 1 |
| Barker-Gear, R | 2 |
| Green, R | 2 |
| Hassan, W | 1 |
| Beuzard, Y | 1 |
| Rosa, J | 1 |
| Franco, R | 1 |
| Silberstein, E | 1 |
| Mayfield, G | 1 |
| Palascak, J | 1 |
| Binnur, K | 1 |
| Firat, G | 1 |
| Sukran, T | 1 |
| Metin, E | 1 |
8 other studies available for phytic acid and HbS Disease
| Article | Year |
|---|---|
Inositol hexaphosphate-loaded red blood cells prevent in vitro sickling.
Topics: Adolescent; Adult; Anemia, Sickle Cell; Erythrocytes; Female; Humans; In Vitro Techniques; Male; Phy | 2010 |
Efficacy of homologous inositol hexaphosphate-loaded red blood cells in sickle transgenic mice.
Topics: Anemia, Sickle Cell; Animals; Arterial Occlusive Diseases; Brain; Disease Models, Animal; Erythrocyt | 2012 |
Effect of inositol hexaphosphate-loaded red blood cells (RBCs) on the rheology of sickle RBCs.
Topics: Anemia, Sickle Cell; Blood Viscosity; Erythrocyte Aggregation; Erythrocytes; Erythrocytes, Abnormal; | 2013 |
Sickling as a function of oxygen delivery: effect of simulated transfusions of stored, fresh and inositol-hexaphosphate-loaded (low affinity) red cells.
Topics: 2,3-Diphosphoglycerate; Anemia, Sickle Cell; Diphosphoglyceric Acids; Erythrocytes, Abnormal; Exchan | 1982 |
Inhibition of sickling after reduction of intracellular hemoglobin concentration with an osmotic pulse: characterization of the density and hemoglobin concentration distributions.
Topics: Anemia, Sickle Cell; Cell Separation; Centrifugation, Zonal; Diphosphates; Erythrocyte Membrane; Ery | 1993 |
Inhibition of erythrocyte sickling by cystamine, a thiol reagent.
Topics: Anemia, Sickle Cell; Cystamine; Erythrocytes; Erythrocytes, Abnormal; Gels; Humans; Oxygen Consumpti | 1976 |
Sickle cells modified by an osmotic pulse in the presence of inositol hexaphosphate have decreased intracellular hemoglobin concentration and decreased in vitro sickling without prolonged in vivo survival.
Topics: Anemia, Sickle Cell; Erythrocyte Aging; Erythrocytes, Abnormal; Hemoglobin, Sickle; Humans; In Vitro | 1992 |
Tc-99m HMDP uptake by the kidney in sickle cell disease.
Topics: Anemia, Sickle Cell; Child; Female; Humans; Kidney; Organotechnetium Compounds; Phytic Acid; Radionu | 1992 |