phytic acid has been researched along with Colorectal Neoplasms in 17 studies
Phytic Acid: Complexing agent for removal of traces of heavy metal ions. It acts also as a hypocalcemic agent.
myo-inositol hexakisphosphate : A myo-inositol hexakisphosphate in which each hydroxy group of myo-inositol is monophosphorylated.
Colorectal Neoplasms: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Inositol hexaphosphate (IP6), a widely found natural bioactive substance in grains, effectively inhibits the progression of colorectal cancer (CRC) when used in combination with inositol (INS)." | 8.31 | The Combination of Inositol Hexaphosphate and Inositol Inhibits Metastasis of Colorectal Cancer Cells by Upregulating Claudin 7. ( Chen, Z; Han, Y; Lan, T; Li, H; Ma, X; Song, Y; Tao, M; Wang, C; Wang, H; Xu, Z; Yang, N, 2023) |
| "To investigate the effects of inositol hexaphosphate (IP6) and inositol (INS) with capecitabine treatment on colorectal cancer (CRC) growth and liver metastasis in mice, we established an orthotopic xenograft mouse model." | 8.02 | Inositol Hexakisphosphate and Inositol Enhance the Inhibition of Colorectal Cancer Growth and Liver Metastasis by Capecitabine in a Mouse Model. ( Chen, C; Ci, Y; Li, C; Li, Q; Li, X; Liu, C; Liu, X; Song, Y, 2021) |
| "Phytic acid (PA) has been demonstrated to have a potent anticarcinogenic activity against colorectal cancer (CRC)." | 7.88 | Phytic acid improves intestinal mucosal barrier damage and reduces serum levels of proinflammatory cytokines in a 1,2-dimethylhydrazine-induced rat colorectal cancer model. ( Chen, C; Cheng, L; Li, X; Liu, C; Song, Y; Yang, F, 2018) |
| "Phytic acid, a major constituent of cereals, pulses, and seeds has been advocated as an important antioxidant component of dietary fibre that affords possible protection against colorectal cancer." | 7.69 | Faecal phytic acid and its relation to other putative markers of risk for colorectal cancer. ( Bartsch, H; Owen, RW; Spiegelhalder, B; Weisgerber, UM, 1996) |
| "Inositol hexaphosphate (IP6), a widely found natural bioactive substance in grains, effectively inhibits the progression of colorectal cancer (CRC) when used in combination with inositol (INS)." | 4.31 | The Combination of Inositol Hexaphosphate and Inositol Inhibits Metastasis of Colorectal Cancer Cells by Upregulating Claudin 7. ( Chen, Z; Han, Y; Lan, T; Li, H; Ma, X; Song, Y; Tao, M; Wang, C; Wang, H; Xu, Z; Yang, N, 2023) |
| "To investigate the effects of inositol hexaphosphate (IP6) and inositol (INS) with capecitabine treatment on colorectal cancer (CRC) growth and liver metastasis in mice, we established an orthotopic xenograft mouse model." | 4.02 | Inositol Hexakisphosphate and Inositol Enhance the Inhibition of Colorectal Cancer Growth and Liver Metastasis by Capecitabine in a Mouse Model. ( Chen, C; Ci, Y; Li, C; Li, Q; Li, X; Liu, C; Liu, X; Song, Y, 2021) |
| "Phytic acid (PA) has been demonstrated to have a potent anticarcinogenic activity against colorectal cancer (CRC)." | 3.88 | Phytic acid improves intestinal mucosal barrier damage and reduces serum levels of proinflammatory cytokines in a 1,2-dimethylhydrazine-induced rat colorectal cancer model. ( Chen, C; Cheng, L; Li, X; Liu, C; Song, Y; Yang, F, 2018) |
| "Phytic acid, a major constituent of cereals, pulses, and seeds has been advocated as an important antioxidant component of dietary fibre that affords possible protection against colorectal cancer." | 3.69 | Faecal phytic acid and its relation to other putative markers of risk for colorectal cancer. ( Bartsch, H; Owen, RW; Spiegelhalder, B; Weisgerber, UM, 1996) |
| "Three types of human colorectal cancer cells were utilized in the present study." | 1.46 | Inositol hexaphosphate hydrolysate competitively binds to AKT to inhibit the proliferation of colon carcinoma. ( Chen, C; Cui, L; Fu, M; Liu, C; Song, Y; Yang, F, 2017) |
| "A human colorectal cancer cell line (HT-29) was used for the study." | 1.42 | Inositol hexaphosphate suppresses growth and induces apoptosis in HT-29 colorectal cancer cells in culture: PI3K/Akt pathway as a potential target. ( Cui, L; Liu, G; Lu, X; Song, Y; Wen, Z, 2015) |
| "Phytic acid (IP-6) is a polyphosphorylated carbohydrate with antitumor activity for many kinds of tumors." | 1.35 | Novel irinotecan-loaded liposome using phytic acid with high therapeutic efficacy for colon tumors. ( Ding, W; Hakoshima, M; Hattori, Y; Kawano, K; Koga, K; Maitani, Y; Shi, L, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (23.53) | 18.2507 |
| 2000's | 1 (5.88) | 29.6817 |
| 2010's | 10 (58.82) | 24.3611 |
| 2020's | 2 (11.76) | 2.80 |
| Authors | Studies |
|---|---|
| Han, Y | 1 |
| Lan, T | 1 |
| Ma, X | 1 |
| Yang, N | 1 |
| Wang, C | 1 |
| Xu, Z | 1 |
| Chen, Z | 1 |
| Tao, M | 1 |
| Li, H | 1 |
| Wang, H | 1 |
| Song, Y | 7 |
| Li, C | 1 |
| Ci, Y | 1 |
| Liu, X | 1 |
| Chen, C | 3 |
| Liu, C | 5 |
| Li, X | 3 |
| Li, Q | 1 |
| Yu, W | 1 |
| Yang, F | 3 |
| Cheng, L | 2 |
| Cui, L | 3 |
| Fu, M | 2 |
| Schröterová, L | 2 |
| Ježková, A | 1 |
| Rudolf, E | 2 |
| Caltová, K | 1 |
| Králová, V | 1 |
| Hanušová, V | 1 |
| Shafie, NH | 1 |
| Mohd Esa, N | 1 |
| Ithnin, H | 1 |
| Md Akim, A | 1 |
| Saad, N | 1 |
| Pandurangan, AK | 1 |
| Liu, G | 1 |
| Wen, Z | 2 |
| Lu, X | 2 |
| Hattori, Y | 1 |
| Shi, L | 1 |
| Ding, W | 1 |
| Koga, K | 1 |
| Kawano, K | 1 |
| Hakoshima, M | 1 |
| Maitani, Y | 1 |
| Prieto, RM | 1 |
| Fiol, M | 1 |
| Perello, J | 1 |
| Estruch, R | 1 |
| Ros, E | 1 |
| Sanchis, P | 1 |
| Grases, F | 1 |
| Hasková, P | 1 |
| Cervinka, M | 1 |
| Suzuki, T | 1 |
| Nishioka, T | 1 |
| Ishizuka, S | 1 |
| Hara, H | 1 |
| Weinberg, ED | 1 |
| Owen, RW | 3 |
| Weisgerber, UM | 1 |
| Spiegelhalder, B | 2 |
| Bartsch, H | 2 |
3 reviews available for phytic acid and Colorectal Neoplasms
| Article | Year |
|---|---|
Association of iron with colorectal cancer.
Topics: Animals; Body Burden; Colorectal Neoplasms; Humans; Iron; Phytic Acid; Transferrin | 1994 |
Dietary and chemopreventive strategies.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Bile Acids and Salts; Calcium; Chemoprevention; Colorectal | 1998 |
Phytate, reactive oxygen species and colorectal cancer.
Topics: Animals; Chromatography, High Pressure Liquid; Colorectal Neoplasms; Feces; Humans; Phytic Acid; Rea | 1998 |
1 trial available for phytic acid and Colorectal Neoplasms
| Article | Year |
|---|---|
Effects of Mediterranean diets with low and high proportions of phytate-rich foods on the urinary phytate excretion.
Topics: Aged; Calcinosis; Colorectal Neoplasms; Cross-Sectional Studies; Diet, Mediterranean; Edible Grain; | 2010 |
13 other studies available for phytic acid and Colorectal Neoplasms
| Article | Year |
|---|---|
The Combination of Inositol Hexaphosphate and Inositol Inhibits Metastasis of Colorectal Cancer Cells by Upregulating Claudin 7.
Topics: Animals; Cell Line, Tumor; Claudins; Colonic Neoplasms; Colorectal Neoplasms; Epithelial-Mesenchymal | 2023 |
Inositol Hexakisphosphate and Inositol Enhance the Inhibition of Colorectal Cancer Growth and Liver Metastasis by Capecitabine in a Mouse Model.
Topics: Animals; Capecitabine; Colorectal Neoplasms; Humans; Inositol; Liver Neoplasms; Mice; Phytic Acid | 2021 |
Inositol hexaphosphate suppresses colorectal cancer cell proliferation via the Akt/GSK-3β/β-catenin signaling cascade in a 1,2-dimethylhydrazine-induced rat model.
Topics: 1,2-Dimethylhydrazine; Animals; Apoptosis; beta Catenin; Cell Proliferation; Colorectal Neoplasms; D | 2017 |
Inositol hexaphosphate hydrolysate competitively binds to AKT to inhibit the proliferation of colon carcinoma.
Topics: Caco-2 Cells; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Gene Expression Regulation | 2017 |
Phytic acid improves intestinal mucosal barrier damage and reduces serum levels of proinflammatory cytokines in a 1,2-dimethylhydrazine-induced rat colorectal cancer model.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Cadherins; Claudin-1; Colon; Colorectal Neoplasms; Cyto | 2018 |
Inositol hexaphosphate limits the migration and the invasiveness of colorectal carcinoma cells in vitro.
Topics: Antineoplastic Agents; Biomarkers, Tumor; Cell Adhesion; Cell Line, Tumor; Cell Movement; Colorectal | 2018 |
Preventive inositol hexaphosphate extracted from rice bran inhibits colorectal cancer through involvement of Wnt/β-catenin and COX-2 pathways.
Topics: Animals; Antineoplastic Agents; beta Catenin; Colorectal Neoplasms; Cyclooxygenase 2; Dietary Fiber; | 2013 |
Inositol hexaphosphate suppresses growth and induces apoptosis in HT-29 colorectal cancer cells in culture: PI3K/Akt pathway as a potential target.
Topics: Apoptosis; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Dose-Response Relationship, Drug | 2015 |
Inositol Hexaphosphate and Inositol Inhibit Colorectal Cancer Metastasis to the Liver in BALB/c Mice.
Topics: Adenocarcinoma; Animals; Colorectal Neoplasms; Female; Inositol; Liver Neoplasms; Mice; Mice, Inbred | 2016 |
Novel irinotecan-loaded liposome using phytic acid with high therapeutic efficacy for colon tumors.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Cell Pro | 2009 |
Effect of phytic acid and inositol on the proliferation and apoptosis of cells derived from colorectal carcinoma.
Topics: Apoptosis; Caspase 3; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Humans; Inositol; | 2010 |
A novel mechanism underlying phytate-mediated biological action-phytate hydrolysates induce intracellular calcium signaling by a Gαq protein-coupled receptor and phospholipase C-dependent mechanism in colorectal cancer cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Caco-2 Cells; Calcium Channel Blockers; Calcium Signalin | 2010 |
Faecal phytic acid and its relation to other putative markers of risk for colorectal cancer.
Topics: Adenoma; Biomarkers, Tumor; Chromatography, High Pressure Liquid; Colorectal Neoplasms; Edible Grain | 1996 |