phytic acid has been researched along with Cell Transformation, Neoplastic in 5 studies
Phytic Acid: Complexing agent for removal of traces of heavy metal ions. It acts also as a hypocalcemic agent.
myo-inositol hexakisphosphate : A myo-inositol hexakisphosphate in which each hydroxy group of myo-inositol is monophosphorylated.
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To test the hypothesis that the antineoplastic activity of phytic acid [inositol hexaphosphate (InsP6)] is a result of rapid intake by the cells and its conversion to lower inositol phosphates (InsP1-5), thereby affecting the intracellular inositol phosphate pool, YAC-1 (mouse T cell leukemia), K562 (human erythroleukemia) and HT-29 (human colon adenocarcinoma) cell lines were incubated at 37 degrees C with [3H]InsP6." | 3.69 | [3H]inositol hexaphosphate (phytic acid) is rapidly absorbed and metabolized by murine and human malignant cells in vitro. ( Shamsuddin, AM; Vucenik, I, 1994) |
| "A striking anticancer action of IP(6) was demonstrated in different experimental models." | 2.43 | Protection against cancer by dietary IP6 and inositol. ( Shamsuddin, AM; Vucenik, I, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vucenik, I | 2 |
| Shamsuddin, AM | 3 |
| Huang, C | 1 |
| Ma, WY | 1 |
| Hecht, SS | 1 |
| Dong, Z | 2 |
| Bode, AM | 1 |
3 reviews available for phytic acid and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Protection against cancer by dietary IP6 and inositol.
Topics: Animals; Antineoplastic Agents; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic | 2006 |
Inositol phosphates have novel anticancer function.
Topics: Animals; Antineoplastic Agents; Cell Division; Cell Transformation, Neoplastic; Dietary Fiber; Human | 1995 |
Signal transduction pathways: targets for chemoprevention of skin cancer.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Cell Transformat | 2000 |
2 other studies available for phytic acid and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
[3H]inositol hexaphosphate (phytic acid) is rapidly absorbed and metabolized by murine and human malignant cells in vitro.
Topics: Adenocarcinoma; Animals; Cell Transformation, Neoplastic; Chromatography, Ion Exchange; Colonic Neop | 1994 |
Inositol hexaphosphate inhibits cell transformation and activator protein 1 activation by targeting phosphatidylinositol-3' kinase.
Topics: Animals; Anticarcinogenic Agents; Cell Line; Cell Transformation, Neoplastic; Epidermal Growth Facto | 1997 |