phytic acid has been researched along with Benign Neoplasms in 20 studies
Phytic Acid: Complexing agent for removal of traces of heavy metal ions. It acts also as a hypocalcemic agent.
myo-inositol hexakisphosphate : A myo-inositol hexakisphosphate in which each hydroxy group of myo-inositol is monophosphorylated.
| Excerpt | Relevance | Reference |
|---|---|---|
| "IP6 (phytic acid) is a naturally occurring compound in plant seeds and grains." | 3.01 | Cellular and Molecular Activities of IP6 in Disease Prevention and Therapy. ( Dilworth, L; Omoruyi, F; Stennett, D, 2023) |
| "Phytic acid (IP6) is a natural antioxidant that is found mainly in cereals and vegetables and, for a long period of time, was considered an antinutritional factor." | 2.53 | Phytic Acid: From Antinutritional to Multiple Protection Factor of Organic Systems. ( Bracarense, AP; Silva, EO, 2016) |
| "A striking anticancer action of IP(6) was demonstrated in different experimental models." | 2.43 | Protection against cancer by dietary IP6 and inositol. ( Shamsuddin, AM; Vucenik, I, 2006) |
| "A striking anticancer effect of IP6 was demonstrated in different experimental models." | 2.42 | Cancer inhibition by inositol hexaphosphate (IP6) and inositol: from laboratory to clinic. ( Shamsuddin, AM; Vucenik, I, 2003) |
| "A striking anti-cancer action of IP6 has been demonstrated both in vivo and in vitro, which is based on the hypotheses that exogenously administered IP6 may be internalized, dephosphorylated to IP(1-5), and inhibit cell growth." | 2.40 | IP6: a novel anti-cancer agent. ( Cole, KE; Shamsuddin, AM; Vucenik, I, 1997) |
| "(1) Phytic acid (PA) is a component of cereal seeds and legumes, therefore its consumption is much higher in a vegan and vegetarian diet compared to a conventional diet." | 1.72 | Phytate Hydrolysate Differently Modulates the Immune Response of Human Healthy and Cancer Colonocytes to Intestinal Bacteria. ( Markiewicz, LH; Ogrodowczyk, AM; Wiczkowski, W; Wróblewska, B, 2022) |
| "A significant anticancer activity of the naturally occurring carbohydrate inositol hexaphosphate (IP(6)) has been reported against numerous cancer models." | 1.32 | Anti-angiogenic activity of inositol hexaphosphate (IP6). ( Eggleton, P; Passaniti, A; Shamsuddin, AM; Tantivejkul, K; Vitolo, MI; Vucenik, I, 2004) |
| "Phytic acid alone did not cause DNA damage and thus, it should not act as a prooxidant." | 1.31 | Protective effect of phytic acid on oxidative DNA damage with reference to cancer chemoprevention. ( Hiraku, Y; Kawanishi, S; Midorikawa, K; Murata, M; Oikawa, S, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.00) | 18.7374 |
| 1990's | 5 (25.00) | 18.2507 |
| 2000's | 8 (40.00) | 29.6817 |
| 2010's | 3 (15.00) | 24.3611 |
| 2020's | 3 (15.00) | 2.80 |
| Authors | Studies |
|---|---|
| Markiewicz, LH | 1 |
| Ogrodowczyk, AM | 1 |
| Wiczkowski, W | 1 |
| Wróblewska, B | 1 |
| Dilworth, L | 1 |
| Stennett, D | 1 |
| Omoruyi, F | 1 |
| Zhang, X | 1 |
| Shi, S | 1 |
| Su, Y | 1 |
| Yang, X | 2 |
| He, S | 1 |
| Wu, J | 1 |
| Zhang, J | 1 |
| Rao, F | 1 |
| Brehm, MA | 1 |
| Windhorst, S | 1 |
| Silva, EO | 1 |
| Bracarense, AP | 1 |
| Fardet, A | 1 |
| Vucenik, I | 4 |
| Shamsuddin, AM | 5 |
| Passaniti, A | 1 |
| Vitolo, MI | 1 |
| Tantivejkul, K | 1 |
| Eggleton, P | 1 |
| Bohn, L | 1 |
| Meyer, AS | 1 |
| Rasmussen, SK | 1 |
| Cole, KE | 1 |
| Ferguson, LR | 1 |
| Harris, PJ | 1 |
| Urbano, G | 1 |
| López-Jurado, M | 1 |
| Aranda, P | 1 |
| Vidal-Valverde, C | 1 |
| Tenorio, E | 1 |
| Porres, J | 1 |
| Birt, DF | 1 |
| Raboy, V | 1 |
| Midorikawa, K | 1 |
| Murata, M | 1 |
| Oikawa, S | 1 |
| Hiraku, Y | 1 |
| Kawanishi, S | 1 |
| Zumkley, H | 1 |
| Losse, H | 1 |
| Messina, M | 1 |
| Barnes, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Acceptability, Tolerance, Satiety and Prebiotic Effect of a New Infant Cereal in Infant Between 5 and 8 Months of Age, at the Beginning of Complementary Feeding[NCT02781298] | 46 participants (Actual) | Interventional | 2014-12-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
12 reviews available for phytic acid and Benign Neoplasms
| Article | Year |
|---|---|
Cellular and Molecular Activities of IP6 in Disease Prevention and Therapy.
Topics: Antioxidants; Apoptosis; Cardiovascular Diseases; Humans; Neoplasms; Phytic Acid | 2023 |
New options of cancer treatment employing InsP
Topics: Animals; Antineoplastic Agents; Cell Proliferation; Humans; Neoplasms; Phytic Acid | 2019 |
Phytic Acid: From Antinutritional to Multiple Protection Factor of Organic Systems.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Cell Line, Tumor; Disease Models, Animal; Edible Gra | 2016 |
New hypotheses for the health-protective mechanisms of whole-grain cereals: what is beyond fibre?
Topics: Anticarcinogenic Agents; Antioxidants; Blood Glucose; Butyric Acid; Cardiovascular Diseases; Diabete | 2010 |
Cancer inhibition by inositol hexaphosphate (IP6) and inositol: from laboratory to clinic.
Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Carcinogens; Colonic Neoplasms; Disease Mod | 2003 |
Protection against cancer by dietary IP6 and inositol.
Topics: Animals; Antineoplastic Agents; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic | 2006 |
Phytate: impact on environment and human nutrition. A challenge for molecular breeding.
Topics: 6-Phytase; Animals; Diet; Environment; Humans; Iron; Neoplasms; Phytic Acid | 2008 |
Inositol phosphates have novel anticancer function.
Topics: Animals; Antineoplastic Agents; Cell Division; Cell Transformation, Neoplastic; Dietary Fiber; Human | 1995 |
IP6: a novel anti-cancer agent.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents; Cell Differentiation; Cell Division; Humans | 1997 |
Protection against cancer by wheat bran: role of dietary fibre and phytochemicals.
Topics: Animals; Anticarcinogenic Agents; Breast Neoplasms; Colonic Neoplasms; Dietary Fiber; Disease Models | 1999 |
The role of phytic acid in legumes: antinutrient or beneficial function?
Topics: Fabaceae; Humans; Intestinal Absorption; Minerals; Neoplasms; Nutritional Physiological Phenomena; P | 2000 |
Soybeans and cancer prevention: a complex food and a complex disease.
Topics: alpha-Amylases; Animals; Estrogens, Non-Steroidal; Glycine max; Humans; Isoflavones; Neoplasms; Phyt | 2001 |
8 other studies available for phytic acid and Benign Neoplasms
| Article | Year |
|---|---|
Phytate Hydrolysate Differently Modulates the Immune Response of Human Healthy and Cancer Colonocytes to Intestinal Bacteria.
Topics: Bacteria; Cytokines; Humans; Immunity; Interleukin-10; Interleukin-8; Mucins; Myeloid Differentiatio | 2022 |
Suramin and NF449 are IP5K inhibitors that disrupt inositol hexakisphosphate-mediated regulation of cullin-RING ligase and sensitize cancer cells to MLN4924/pevonedistat.
Topics: Benzenesulfonates; Cullin Proteins; Cyclopentanes; Enzyme Inhibitors; HCT116 Cells; HEK293 Cells; Hu | 2020 |
Anti-angiogenic activity of inositol hexaphosphate (IP6).
Topics: Angiogenesis Inhibitors; Animals; Aorta; Calreticulin; Cattle; Cell Division; Endothelium, Vascular; | 2004 |
Inositol hexaphosphate, a natural substance found in whole kernel corn and brown rice, activates natural killer cell function - inhibits cancer.
Topics: Animals; Anti-HIV Agents; Antineoplastic Agents; Complementary Therapies; Cooking; Edible Grain; HIV | 1998 |
Seeds for a better future: 'low phytate' grains help to overcome malnutrition and reduce pollution.
Topics: Aged; Animals; Biotechnology; Child; Developed Countries; Developing Countries; Diet; Fabaceae; Huma | 2001 |
Protective effect of phytic acid on oxidative DNA damage with reference to cancer chemoprevention.
Topics: Binding Sites; Chemoprevention; Copper; Deoxyadenosines; DNA; DNA Damage; Drug Interactions; Genes, | 2001 |
[Clinical aspects and therapy of hypercalcemia].
Topics: Glucocorticoids; Humans; Hypercalcemia; Hyperthyroidism; Neoplasms; Oxalates; Phosphates; Phytic Aci | 1977 |
The role of soy products in reducing risk of cancer.
Topics: Animals; Glycine max; Humans; Isoflavones; Neoplasms; Phytic Acid; Phytosterols; Protease Inhibitors | 1991 |