Page last updated: 2024-10-19

phytic acid and Anemia, Iron-Deficiency

phytic acid has been researched along with Anemia, Iron-Deficiency in 26 studies

Phytic Acid: Complexing agent for removal of traces of heavy metal ions. It acts also as a hypocalcemic agent.
myo-inositol hexakisphosphate : A myo-inositol hexakisphosphate in which each hydroxy group of myo-inositol is monophosphorylated.

Anemia, Iron-Deficiency: Anemia characterized by decreased or absent iron stores, low serum iron concentration, low transferrin saturation, and low hemoglobin concentration or hematocrit value. The erythrocytes are hypochromic and microcytic and the iron binding capacity is increased.

Research Excerpts

ExcerptRelevanceReference
"Few studies have evaluated the impact of fortification with iron-rich foods such as amaranth grain and multi-micronutrient powder (MNP) containing low doses of highly bioavailable iron to control iron deficiency anemia (IDA) in children."2.77Maize porridge enriched with a micronutrient powder containing low-dose iron as NaFeEDTA but not amaranth grain flour reduces anemia and iron deficiency in Kenyan preschool children. ( Brouwer, ID; Kok, FJ; Macharia-Mutie, CW; Moretti, D; Mwangi, AM; Omusundi, AM; Van den Briel, N; Zimmermann, MB, 2012)
"To evaluate the effect of consuming sous vide cooked salmon fish on non-heme iron bioavailability from a bean meal, rich in phytate, in iron-deficient women."2.73Oily fish increases iron bioavailability of a phytate rich meal in young iron deficient women. ( Carbajal, A; Fairweather-Tait, SJ; Navas-Carretero, S; Pedrosa, MM; Pérez-Granados, AM; Roe, MA; Sarriá, B; Vaquero, MP, 2008)
"Phytic acid (PA) is a major inhibitor of iron bioavailability from beans, and high PA concentrations might limit the positive effect of biofortified beans (BBs) on iron status."1.43In Rwandese Women with Low Iron Status, Iron Absorption from Low-Phytic Acid Beans and Biofortified Beans Is Comparable, but Low-Phytic Acid Beans Cause Adverse Gastrointestinal Symptoms. ( Boy, E; Campion, B; Gahutu, JB; Moretti, D; Petry, N; Rohner, F; Tugirimana, PL; Wirth, JP; Zimmerman, MB; Zwahlen, C, 2016)
") lines with contrasting Fe bioavailability (ie."1.39High bioavailability iron maize (Zea mays L.) developed through molecular breeding provides more absorbable iron in vitro (Caco-2 model) and in vivo (Gallus gallus). ( Glahn, RP; Hoekenga, OA; Kochian, LV; Tako, E, 2013)
"The objective of this study was to evaluate iron bioavailability of maize genotypes, and analyze the correlation between in vitro and in vivo methods."1.38Iron bioavailability of different maize genotypes developed in a breeding program: in vitro and in vivo studies. ( Costa, NM; Guimarães, PE; Martino, HS; Nakajima, VM; Oliveira, PV; Queiroz, VA, 2012)
" The main objective of the study was to determine whether a change from red beans to white beans in the complementary food recipe would improve iron bioavailability from the mixture, as recent studies had indicated that iron bioavailability in white beans is significantly higher compared to that in the colored beans."1.36Use of white beans instead of red beans may improve iron bioavailability from a Tanzanian complementary food mixture. ( Glahn, RP; Lung'aho, MG, 2010)
"The main objective of this study was to assess the amount of bioavailable iron in Kenyan complementary foods and to determine whether strategies such as food diversification using locally available foods would improve the bioavailability of iron from these foods."1.35In vitro estimates of iron bioavailability in some Kenyan complementary foods. ( Glahn, RP; Lung'aho, MG, 2009)
" Fe bioavailability and utilization in wheat bread (WB) and corn tortillas (CT) fortified with various Fe sources was assessed after the depletion and repletion periods."1.33Cooking and Fe fortification have different effects on Fe bioavailability of bread and tortillas. ( Hernández, M; López-Alarcón, M; Montalvo, I; Moreno, A; Sousa, V; Villalpando, S, 2006)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (7.69)18.2507
2000's10 (38.46)29.6817
2010's14 (53.85)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Podder, R1
Tar'an, B1
Tyler, RT1
Henry, CJ1
DellaValle, DM1
Vandenberg, A1
Swaminathan, S1
Ghosh, S1
Varghese, JS1
Sachdev, HS1
Kurpad, AV1
Thomas, T1
Nakajima, VM1
Costa, NM1
Martino, HS1
Queiroz, VA1
Guimarães, PE1
Oliveira, PV1
Beck, KL1
Conlon, CA1
Kruger, R1
Coad, J1
Petry, N1
Rohner, F1
Gahutu, JB1
Campion, B1
Boy, E1
Tugirimana, PL1
Zimmerman, MB1
Zwahlen, C1
Wirth, JP1
Moretti, D3
Lung'aho, MG2
Glahn, RP3
Trinidad, TP1
Mallillin, AC1
Sagum, RS1
Briones, DP1
Encabo, RR1
Juliano, BO1
Prosser, NR1
Heath, AL2
Williams, SM1
Gibson, RS2
Monárrez-Espino, J1
López-Alarcón, M2
Greiner, T1
Murgia, I1
Arosio, P1
Tarantino, D1
Soave, C1
Macharia-Mutie, CW1
Van den Briel, N1
Omusundi, AM1
Mwangi, AM1
Kok, FJ1
Zimmermann, MB2
Brouwer, ID2
Chang, S1
Huang, Z1
Ma, Y1
Piao, J1
Yang, X1
Zeder, C1
Hurrell, RF2
Egli, I1
Abizari, AR1
Armar-Klemesu, M1
Tako, E1
Hoekenga, OA1
Kochian, LV1
Sandstead, HH1
Fidler, MC1
Davidsson, L1
Walczyk, T1
Hernández, M1
Sousa, V1
Villalpando, S1
Moreno, A1
Montalvo, I1
Zhang, H1
Onning, G1
Oste, R1
Gramatkovski, E1
Hulthén, L1
Navas-Carretero, S1
Pérez-Granados, AM1
Sarriá, B1
Carbajal, A1
Pedrosa, MM1
Roe, MA1
Fairweather-Tait, SJ1
Vaquero, MP1
Brunvand, L1
Henriksen, C1
Larsson, M1
Sandberg, AS1
Bakr, AA1
Skeaff, CM1
Zijp, IM1
Korver, O1
Tijburg, LB1
Mendoza, C1
Viteri, FE1
Lönnerdal, B1
Raboy, V1
Young, KA1
Brown, KH1
Bhargava, A1
Bouis, HE1
Scrimshaw, NS1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT02215278]25 participants (Actual)Interventional2014-02-28Completed
Improving Iron Status of Children in a Semi-arid Area of Kenya: the Potential of Amaranth Grain Flour[NCT01224535]270 participants (Anticipated)Interventional2010-10-31Completed
Improving Iron Status Through Consumption Of Iron Fortified Cowpea: An Intervention Study[NCT01208363]240 participants (Anticipated)Interventional2010-09-30Completed
[NCT01135576]122 participants (Actual)Interventional2008-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for phytic acid and Anemia, Iron-Deficiency

ArticleYear
Dietary determinants of and possible solutions to iron deficiency for young women living in industrialized countries: a review.
    Nutrients, 2014, Sep-19, Volume: 6, Issue:9

    Topics: Anemia, Iron-Deficiency; Ascorbic Acid; Calcium, Dietary; Developed Countries; Diet; Humans; Intesti

2014
Biofortification for combating 'hidden hunger' for iron.
    Trends in plant science, 2012, Volume: 17, Issue:1

    Topics: Anemia, Iron-Deficiency; Crops, Agricultural; Food, Fortified; Humans; Iron Deficiencies; Iron, Diet

2012
Human zinc deficiency: discovery to initial translation.
    Advances in nutrition (Bethesda, Md.), 2013, Jan-01, Volume: 4, Issue:1

    Topics: Anemia, Iron-Deficiency; Bread; Diet; Egypt; Flour; Humans; Iron, Dietary; Male; Nutritional Status;

2013
Effect of tea and other dietary factors on iron absorption.
    Critical reviews in food science and nutrition, 2000, Volume: 40, Issue:5

    Topics: Anemia, Iron-Deficiency; Ascorbic Acid; Biological Availability; Calcium; Diet; Dietary Proteins; Fl

2000

Trials

8 trials available for phytic acid and Anemia, Iron-Deficiency

ArticleYear
Influence of an iron intervention on the zinc status of young adult New Zealand women with mild iron deficiency.
    The British journal of nutrition, 2010, Volume: 104, Issue:5

    Topics: Adult; Alkaline Phosphatase; Anemia, Iron-Deficiency; Ascorbic Acid; Counseling; Diet Surveys; Dieta

2010
Randomized placebo-controlled trial of guava juice as a source of ascorbic acid to reduce iron deficiency in Tarahumara indigenous schoolchildren of northern Mexico.
    Journal of the American College of Nutrition, 2011, Volume: 30, Issue:3

    Topics: Anemia, Iron-Deficiency; Ascorbic Acid; Beverages; Child; Diet; Energy Intake; Female; Ferritins; He

2011
Maize porridge enriched with a micronutrient powder containing low-dose iron as NaFeEDTA but not amaranth grain flour reduces anemia and iron deficiency in Kenyan preschool children.
    The Journal of nutrition, 2012, Volume: 142, Issue:9

    Topics: Amaranthus; Anemia, Iron-Deficiency; Anthropometry; Child, Preschool; Edetic Acid; Edible Grain; Fem

2012
Mixture of ferric sodium ethylenediaminetetraacetate (NaFeEDTA) and ferrous sulfate: an effective iron fortificant for complementary foods for young Chinese children.
    Food and nutrition bulletin, 2012, Volume: 33, Issue:2

    Topics: Anemia, Iron-Deficiency; Child Rearing; Child, Preschool; China; Cooking; Cross-Over Studies; Diet;

2012
Whole cowpea meal fortified with NaFeEDTA reduces iron deficiency among Ghanaian school children in a malaria endemic area.
    The Journal of nutrition, 2012, Volume: 142, Issue:10

    Topics: Anemia, Iron-Deficiency; Child; Child, Preschool; Double-Blind Method; Edetic Acid; Fabaceae; Female

2012
Iron absorption from fish sauce and soy sauce fortified with sodium iron EDTA.
    The American journal of clinical nutrition, 2003, Volume: 78, Issue:2

    Topics: Adult; Anemia, Iron-Deficiency; Biological Availability; Deferoxamine; Diet; Edetic Acid; Female; Fe

2003
Improved iron bioavailability in an oat-based beverage: the combined effect of citric acid addition, dephytinization and iron supplementation.
    European journal of nutrition, 2007, Volume: 46, Issue:2

    Topics: 6-Phytase; Adult; Anemia, Iron-Deficiency; Avena; Beverages; Biological Availability; Citric Acid; D

2007
Oily fish increases iron bioavailability of a phytate rich meal in young iron deficient women.
    Journal of the American College of Nutrition, 2008, Volume: 27, Issue:1

    Topics: Adolescent; Adult; Anemia, Iron-Deficiency; Animals; Biological Availability; Cross-Over Studies; Er

2008

Other Studies

14 other studies available for phytic acid and Anemia, Iron-Deficiency

ArticleYear
Iron Fortification of Lentil (Lens culinaris Medik.) to Address Iron Deficiency.
    Nutrients, 2017, Aug-11, Volume: 9, Issue:8

    Topics: Anemia, Iron-Deficiency; Colorimetry; Cooking; Food Analysis; Food Handling; Food, Fortified; Genoty

2017
Dietary Iron Intake and Anemia Are Weakly Associated, Limiting Effective Iron Fortification Strategies in India.
    The Journal of nutrition, 2019, 05-01, Volume: 149, Issue:5

    Topics: Adolescent; Adult; Anemia; Anemia, Iron-Deficiency; Ascorbic Acid; Diet; Energy Intake; Female; Food

2019
Iron bioavailability of different maize genotypes developed in a breeding program: in vitro and in vivo studies.
    Archivos latinoamericanos de nutricion, 2012, Volume: 62, Issue:2

    Topics: Anemia, Iron-Deficiency; Animals; Biological Assay; Biological Availability; Breeding; Dialysis; Foo

2012
In Rwandese Women with Low Iron Status, Iron Absorption from Low-Phytic Acid Beans and Biofortified Beans Is Comparable, but Low-Phytic Acid Beans Cause Adverse Gastrointestinal Symptoms.
    The Journal of nutrition, 2016, Volume: 146, Issue:5

    Topics: Adolescent; Adult; Anemia, Iron-Deficiency; Biological Availability; Diet; Digestion; Female; Food,

2016
In vitro estimates of iron bioavailability in some Kenyan complementary foods.
    Food and nutrition bulletin, 2009, Volume: 30, Issue:2

    Topics: Anemia, Iron-Deficiency; Biological Availability; Caco-2 Cells; Diet; Digestion; Ferritins; Food, Fo

2009
Iron absorption from brown rice/brown rice-based meal and milled rice/milled rice-based meal.
    International journal of food sciences and nutrition, 2009, Volume: 60, Issue:8

    Topics: Adult; Anemia, Iron-Deficiency; Animals; Beverages; Dietary Fiber; Food Handling; Humans; Intestinal

2009
Use of white beans instead of red beans may improve iron bioavailability from a Tanzanian complementary food mixture.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 2010, Volume: 80, Issue:1

    Topics: Anemia, Iron-Deficiency; Bifidobacterium; Biological Availability; Caco-2 Cells; Digestion; Enterocy

2010
High bioavailability iron maize (Zea mays L.) developed through molecular breeding provides more absorbable iron in vitro (Caco-2 model) and in vivo (Gallus gallus).
    Nutrition journal, 2013, Jan-04, Volume: 12

    Topics: Anemia, Iron-Deficiency; Animals; Biological Availability; Caco-2 Cells; Cation Transport Proteins;

2013
Cooking and Fe fortification have different effects on Fe bioavailability of bread and tortillas.
    Journal of the American College of Nutrition, 2006, Volume: 25, Issue:1

    Topics: Anemia, Iron-Deficiency; Animals; Biological Availability; Bread; Cooking; Female; Ferrous Compounds

2006
Iron deficiency among pregnant Pakistanis in Norway and the content of phytic acid in their diet.
    Acta obstetricia et gynecologica Scandinavica, 1995, Volume: 74, Issue:7

    Topics: Adult; Anemia, Iron-Deficiency; Cross-Sectional Studies; Feeding Behavior; Female; Ferritins; Hemogl

1995
Effect of Egyptian cooking methods of faba beans on its nutritive value, dietary protein utilization and iron deficiency anemia. 1. The role of main technological pretreatments.
    Plant foods for human nutrition (Dordrecht, Netherlands), 1996, Volume: 49, Issue:1

    Topics: Adult; Amino Acids; Anemia, Iron-Deficiency; Cooking; Dietary Proteins; Egypt; Fabaceae; Food Handli

1996
The relative validity of a computerized food frequency questionnaire for estimating intake of dietary iron and its absorption modifiers.
    European journal of clinical nutrition, 2000, Volume: 54, Issue:7

    Topics: Adult; Anemia, Iron-Deficiency; Ascorbic Acid; Biological Availability; Calcium, Dietary; Coffee; Co

2000
Absorption of iron from unmodified maize and genetically altered, low-phytate maize fortified with ferrous sulfate or sodium iron EDTA.
    The American journal of clinical nutrition, 2001, Volume: 73, Issue:1

    Topics: Adult; Analysis of Variance; Anemia, Iron-Deficiency; Edetic Acid; Female; Ferric Compounds; Ferrous

2001
Dietary intakes and socioeconomic factors are associated with the hemoglobin concentration of Bangladeshi women.
    The Journal of nutrition, 2001, Volume: 131, Issue:3

    Topics: Adolescent; Adult; Algorithms; Anemia, Iron-Deficiency; Anthropometry; Bangladesh; Biological Availa

2001