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physostigmine heptyl and Acute Confusional Senile Dementia

physostigmine heptyl has been researched along with Acute Confusional Senile Dementia in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.56)18.7374
1990's11 (61.11)18.2507
2000's3 (16.67)29.6817
2010's2 (11.11)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Boido, V; Carotti, A; Catto, M; Giangreco, I; Nicolotti, O; Novelli, F; Pisani, L; Sparatore, A; Sparatore, F; Tasso, B; Tonelli, M1
Andrisano, V; Bartolini, M; Belluti, F; Bisi, A; Di Marzo, V; Gobbi, S; Ligresti, A; Montanari, S; Mor, M; Rampa, A; Rivara, S; Scalvini, L1
Li, X; Wang, S; Wang, Y; Wang, Z; Zhang, H1
Rakonczay, Z1
Chapin, D; Hubbard, ST; Jones, SB; Liston, DR; Nason, D; Nielsen, JA; Ramirez, A; Shalaby, IA; Villalobos, A; White, WF1
Imbimbo, BP; Luzzana, M; Mosca, A; Onelli, E; Paleari, R; Rosti, E1
Barchowsky, A; Block, GA; Cutler, NR; Reines, SA; Sawin, SF; Sramek, JJ1
Cutler, NR; Sramek, JJ2
Canal, N; Imbimbo, BP1
Ghezzi, A; Imbimbo, BP; Luzzana, M; Mosca, A; Paleari, R1
Alberoni, M; Imbimbo, BP; Lucca, U; Lucchelli, F; Thal, LJ1
Calcagnini, G; Fieschi, C; Frontoni, M; Giubilei, F; Imbimbo, BP; Lino, S; Santini, M; Strano, S; Tisei, P1
Scheltens, P; Verhey, FR1
Imbimbo, BP; Lucca, U; Lucchelli, F; Martelli, P; Thal, LJ; Troetel, WM1
Braida, D; Sala, M1
Becker, RE; Hutt, V; Imbimbo, BP; Unni, LK1
Brufani, M; Marta, M; Pomponi, M1

Reviews

2 review(s) available for physostigmine heptyl and Acute Confusional Senile Dementia

ArticleYear
Recent advance on carbamate-based cholinesterase inhibitors as potential multifunctional agents against Alzheimer's disease.
    European journal of medicinal chemistry, 2022, Oct-05, Volume: 240

    Topics: Aged; Alzheimer Disease; Carbamates; Cholinesterase Inhibitors; Humans; Ligands

2022
Eptastigmine: ten years of pharmacology, toxicology, pharmacokinetic, and clinical studies.
    CNS drug reviews, 2001,Winter, Volume: 7, Issue:4

    Topics: Acetylcholine; Acetylcholinesterase; Activities of Daily Living; Agranulocytosis; Alzheimer Disease; Animals; Behavior, Animal; Biogenic Monoamines; Brain; Cholinesterase Inhibitors; Cognition Disorders; Erythrocytes; Humans; Learning; Memory; Physostigmine; Randomized Controlled Trials as Topic

2001

Trials

6 trial(s) available for physostigmine heptyl and Acute Confusional Senile Dementia

ArticleYear
A patient-side technique for real-time measurement of acetylcholinesterase activity during monitoring of eptastigmine treatment.
    Therapeutic drug monitoring, 1995, Volume: 17, Issue:3

    Topics: Acetylcholinesterase; Adolescent; Adult; Alzheimer Disease; Cholinesterase Inhibitors; Double-Blind Method; Drug Monitoring; Female; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Physostigmine; Reproducibility of Results

1995
A multiple-dose safety trial of eptastigmine in Alzheimer's disease, with pharmacodynamic observations of red blood cell cholinesterase.
    Life sciences, 1995, Volume: 56, Issue:5

    Topics: Acetylcholinesterase; Aged; Aged, 80 and over; Alzheimer Disease; Butyrylcholinesterase; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Erythrocytes; Female; Humans; Male; Middle Aged; Physostigmine; Placebos

1995
The target population in phase I clinical trials of cholinergic compounds in Alzheimer disease: the role of the "bridging study".
    Alzheimer disease and associated disorders, 1995,Fall, Volume: 9, Issue:3

    Topics: Alzheimer Disease; Cholinergic Agents; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Tolerance; Humans; Physostigmine; Safety; Tacrine

1995
Relationship between pharmacodynamic activity and cognitive effects of eptastigmine in patients with Alzheimer's disease. Eptastigmine Study Group.
    Clinical pharmacology and therapeutics, 1996, Volume: 60, Issue:2

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Cognition; Double-Blind Method; Drug Administration Schedule; Erythrocytes; Female; Humans; Male; Middle Aged; Physostigmine

1996
A 25-week placebo-controlled study of eptastigmine in patients with Alzheimer disease.
    Alzheimer disease and associated disorders, 1998, Volume: 12, Issue:4

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Mental Status Schedule; Middle Aged; Neuropsychological Tests; Physostigmine; Treatment Outcome

1998
Efficacy and safety of eptastigmine for the treatment of patients with Alzheimer's disease.
    Neurology, 1999, Mar-10, Volume: 52, Issue:4

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Double-Blind Method; Female; Humans; Male; Middle Aged; Physostigmine; Treatment Outcome

1999

Other Studies

10 other study(ies) available for physostigmine heptyl and Acute Confusional Senile Dementia

ArticleYear
Quinolizidinyl derivatives of bi- and tricyclic systems as potent inhibitors of acetyl- and butyrylcholinesterase with potential in Alzheimer's disease.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:6

    Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Butyrylcholinesterase; Cattle; Cholinesterase Inhibitors; Crystallography, X-Ray; Dose-Response Relationship, Drug; Erythrocytes; Models, Molecular; Molecular Structure; Quinolizidines; Stereoisomerism; Structure-Activity Relationship

2011
Fatty Acid Amide Hydrolase (FAAH), Acetylcholinesterase (AChE), and Butyrylcholinesterase (BuChE): Networked Targets for the Development of Carbamates as Potential Anti-Alzheimer's Disease Agents.
    Journal of medicinal chemistry, 2016, 07-14, Volume: 59, Issue:13

    Topics: Acetylcholinesterase; Alzheimer Disease; Amidohydrolases; Butyrylcholinesterase; Carbamates; Cell Line, Tumor; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Models, Molecular; Molecular Structure; Structure-Activity Relationship

2016
Potencies and selectivities of inhibitors of acetylcholinesterase and its molecular forms in normal and Alzheimer's disease brain.
    Acta biologica Hungarica, 2003, Volume: 54, Issue:2

    Topics: Acetylcholinesterase; Alzheimer Disease; Benzazepines; Brain; Butyrylcholinesterase; Carbamates; Cerebral Cortex; Cholinesterase Inhibitors; Edrophonium; Humans; In Vitro Techniques; Phenylcarbamates; Physostigmine; Rivastigmine; Tacrine; Trichlorfon

2003
Pharmacology of selective acetylcholinesterase inhibitors: implications for use in Alzheimer's disease.
    European journal of pharmacology, 2004, Feb-13, Volume: 486, Issue:1

    Topics: Acetylcholine; Alzheimer Disease; Animals; Brain; Butyrylcholinesterase; Cholinesterase Inhibitors; Donepezil; Dose-Response Relationship, Drug; Humans; Indans; Male; Mice; Physostigmine; Piperidines; Rats; Rats, Sprague-Dawley; Tacrine

2004
Scientific and ethical concerns in clinical trials in Alzheimer's patients: the bridging study.
    European journal of clinical pharmacology, 1995, Volume: 48, Issue:6

    Topics: Alzheimer Disease; Cholinesterase Inhibitors; Clinical Trials as Topic; Dihydropyridines; Ethics, Medical; Humans; Nootropic Agents; Oximes; Physostigmine; Psychotropic Drugs; Pyridines; Tacrine; Thiadiazoles

1995
Pharmacodynamic monitoring of eptastigmine in capillary blood.
    European journal of clinical pharmacology, 1996, Volume: 50, Issue:5

    Topics: Acetylcholinesterase; Adult; Alzheimer Disease; Butyrylcholinesterase; Cholinesterase Inhibitors; Humans; Male; Middle Aged; Physostigmine; Time Factors

1996
Cardiac autonomic dysfunction in patients with Alzheimer disease: possible pathogenetic mechanisms.
    Alzheimer disease and associated disorders, 1998, Volume: 12, Issue:4

    Topics: Acetylcholinesterase; Aged; Alzheimer Disease; Autonomic Nervous System; Autonomic Nervous System Diseases; Cholinesterase Inhibitors; Electrocardiography; Erythrocytes; Female; Fourier Analysis; Heart; Heart Rate; Humans; Male; Middle Aged; Physostigmine; Signal Processing, Computer-Assisted

1998
[Drugs for Alzheimer disease: what will the minister decide].
    Tijdschrift voor gerontologie en geriatrie, 1998, Volume: 29, Issue:6

    Topics: Activities of Daily Living; Aged; Alzheimer Disease; Cholinesterase Inhibitors; Drug Approval; Female; Health Policy; Humans; Male; Middle Aged; Netherlands; Neurobehavioral Manifestations; Physostigmine; Religion and Medicine

1998
Kinetics of cholinesterase inhibition by eptastigmine in man.
    European journal of clinical pharmacology, 1991, Volume: 41, Issue:1

    Topics: Adult; Alzheimer Disease; Cholinesterase Inhibitors; Humans; Kinetics; Male; Physostigmine

1991
Anticholinesterase activity of a new carbamate, heptylphysostigmine, in view of its use in patients with Alzheimer-type dementia.
    European journal of biochemistry, 1986, May-15, Volume: 157, Issue:1

    Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Cholinesterase Inhibitors; Eels; In Vitro Techniques; Kinetics; Mathematics; Physostigmine

1986