physalaemin has been researched along with Lung-Neoplasms* in 3 studies
1 review(s) available for physalaemin and Lung-Neoplasms
Article | Year |
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Preneoplasia and neoplasia of the bronchus, esophagus, and colon: the use of markers in determining phenotypes and classification.
Topics: alpha-Fetoproteins; Amines; Animals; Bombesin; Bronchi; Calcitonin; Calmodulin; Carcinoembryonic Antigen; Carcinoma in Situ; Carcinoma, Bronchogenic; Chorionic Gonadotropin; Cytoskeletal Proteins; Esophageal Neoplasms; Glycogen; Growth Hormone; Hormones; Humans; Intestinal Neoplasms; Lung Neoplasms; Parathyroid Hormone; Physalaemin; Placental Lactogen; Precancerous Conditions; Somatostatin; Vasoactive Intestinal Peptide | 1985 |
2 other study(ies) available for physalaemin and Lung-Neoplasms
Article | Year |
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Physalaemin-like immunoreactivity from human lung small cell carcinoma: isocratic reversed-phase HPLC analysis of the chemically modified peptide.
Topics: Animals; Carcinoma, Small Cell; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Kinins; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Physalaemin; Radioimmunoassay; Transplantation, Heterologous | 1985 |
Physalaemin: an amphibian tachykinin in human lung small-cell carcinoma.
Immunoreactivity to the amphibian peptide physalaemin was characterized from extracts of a human lung small-cell carcinoma by immunological, chemical, and pharmacological means. Tumor-related peptide cross-reacted with three antiserums to physalaemin to yield 1.1 to 1.6 nanomoles per gram of tissue. Physalaemin and tumor peptide had similar retention times on high-performance liquid chromatography after chemical and enzymic modifications that included pH changes, oxone oxidation, use of a hydrophilic ion-pairing reagent, and digestion with trypsin and pyroglutamate aminopeptidase. Both physalaemin and the tumor peptide produced a contractile response of isolated guinea pig ileum at threshold concentrations of approximately 100 to 150 picograms per milliliter. These data suggest that small-cell carcinoma of the lung contains a physalaemin-like peptide that has structural and biological homology to its amphibian counterpart. Topics: Carcinoma, Small Cell; Chromatography, High Pressure Liquid; Cross Reactions; Humans; Immune Sera; Kinins; Lung Neoplasms; Oxidation-Reduction; Peptides; Physalaemin; Tachykinins | 1983 |