Page last updated: 2024-10-20

phthalic acid and Preterm Birth

phthalic acid has been researched along with Preterm Birth in 28 studies

phthalic acid: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7178
phthalic acid : A benzenedicarboxylic acid cosisting of two carboxy groups at ortho positions.

Research Excerpts

ExcerptRelevanceReference
"Parental preconception exposure to select phenols and phthalates was previously associated with increased risk of preterm birth in single chemical analyses."8.02Parental preconception exposure to phenol and phthalate mixtures and the risk of preterm birth. ( Calafat, AM; Demokritou, M; Hauser, R; Lee, A; Messerlian, C; Mustieles, V; Souter, I; Vagios, S; Williams, PL; Wylie, BJ; Zhang, Y, 2021)
"Higher pregnancy-averaged phthalic acid, low molecular weight phthalate (LMWP), high molecular weight phthalate (HMWP) and di-2-ethylhexylphthalate (DEHP) concentrations tended to be associated with lower fetal weight SDS across gestation."4.02Maternal phthalate urine concentrations, fetal growth and adverse birth outcomes. A population-based prospective cohort study. ( Asimakopoulos, AG; Jaddoe, VWV; Kannan, K; Martinez-Moral, MP; Philips, EM; Santos, S; Sol, CM; Trasande, L; van Zwol-Janssens, C, 2021)
"Parental preconception exposure to select phenols and phthalates was previously associated with increased risk of preterm birth in single chemical analyses."4.02Parental preconception exposure to phenol and phthalate mixtures and the risk of preterm birth. ( Calafat, AM; Demokritou, M; Hauser, R; Lee, A; Messerlian, C; Mustieles, V; Souter, I; Vagios, S; Williams, PL; Wylie, BJ; Zhang, Y, 2021)
" An assessment of non-linear trends showed some evidence of non-monotonic dose-response relationships between phthalates and PTB."1.56Associations of prenatal urinary phthalate exposure with preterm birth: the Maternal-Infant Research on Environmental Chemicals (MIREC) Study. ( Arbuckle, TE; Braun, JM; Chen, A; Fraser, WD; Hu, JMY; Janssen, P; Lanphear, BP; McCandless, LC; Platt, RW, 2020)
"Preterm birth is a leading cause of neonatal mortality, with a variety of contributing causes and risk factors."1.40Environmental phthalate exposure and preterm birth. ( Ferguson, KK; McElrath, TF; Meeker, JD, 2014)
"Preterm birth is a significant public health problem, affecting over 1 in 10 live births and contributing largely to infant mortality and morbidity."1.40Variability in urinary phthalate metabolite levels across pregnancy and sensitive windows of exposure for the risk of preterm birth. ( Ferguson, KK; Ko, YA; McElrath, TF; Meeker, JD; Mukherjee, B, 2014)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's10 (35.71)24.3611
2020's18 (64.29)2.80

Authors

AuthorsStudies
Mesquita, I1
Lorigo, M1
Cairrao, E1
Yland, JJ1
Zhang, Y3
Williams, PL2
Mustieles, V2
Vagios, S2
Souter, I2
Calafat, AM3
Hauser, R3
Messerlian, C3
Cathey, AL3
Aung, MT2
Watkins, DJ4
Rosario, ZY2
Vélez Vega, CM1
Alshawabkeh, AN3
Cordero, JF4
Mukherjee, B4
Meeker, JD7
Vélez, C1
Seymore, TN1
Rivera-Núñez, Z1
Stapleton, PA1
Adibi, JJ1
Barrett, ES3
Welch, BM1
Keil, AP1
Buckley, JP1
Christenbury, KE1
Engel, SM1
O'Brien, KM1
Rosen, EM2
James-Todd, T1
Zota, AR1
Ferguson, KK5
Bush, NR1
Nguyen, RHN2
Sathyanarayana, S2
Swan, SH3
Cantonwine, DE1
McElrath, TF5
Aalborg, J1
Dabelea, D1
Starling, AP1
Bradman, A1
Eskenazi, B1
Harley, KG1
Holland, N1
Bloom, MS1
Newman, RB1
Wenzel, AG1
Braun, JM2
Lanphear, BP2
Yolton, K1
Factor-Litvak, P1
Herbstman, JB1
Rauh, VA1
Drobnis, EZ1
Sparks, AE1
Redmon, JB1
Wang, C1
Binder, AM1
Michels, KB1
Baird, DD1
Jukic, AMZ1
Weinberg, CR1
Wilcox, AJ1
Rich, DQ2
Weinberger, B2
Padmanabhan, V1
Hertz-Picciotto, I1
Schmidt, RJ1
Wang, X1
Wang, LL1
Tian, YK1
Xiong, SM1
Liu, YJ1
Zhang, HN1
Shen, XB1
Zhou, YZ1
Chen, Y1
Xiao, H1
Namat, A1
Liu, J1
Ruan, F1
Xu, S1
Li, R1
Xia, W1
Ali, A1
Jørgensen, JS1
Lamont, RF2
Park, S1
Hao, W1
Zeng, L1
Pennathur, S1
Rosario-Pabón, Z1
Vélez-Vega, CM1
Alshawabkeh, A1
Stroustrup, A1
Zhang, X1
Spear, E1
Bandyopadhyay, S1
Narasimhan, S1
Meher, AK1
Choi, J1
Qi, G1
Poindexter, BB1
Teitelbaum, SL1
Andra, SS1
Gennings, C1
Aschner, JL1
Sultan, W1
Arain, FH1
Mansoor, S1
Amir, A1
Broe, A1
Pottegård, A1
Hallas, J1
Ahern, TP1
Damkier, P1
Bush, N1
Etzel, RA1
Hu, JMY1
Arbuckle, TE1
Janssen, P1
Platt, RW1
Chen, A1
Fraser, WD1
McCandless, LC1
Qian, Y1
Shao, H1
Ying, X1
Huang, W1
Hua, Y1
Santos, S1
Sol, CM1
van Zwol-Janssens, C1
Philips, EM1
Asimakopoulos, AG1
Martinez-Moral, MP1
Kannan, K1
Jaddoe, VWV1
Trasande, L1
Wylie, BJ1
Demokritou, M1
Lee, A1
Zhong, Q1
Liu, HL1
Fu, H1
Niu, QS1
Wu, HB1
Huang, F1
Gao, H1
Wang, YF1
Huang, K1
Han, Y1
Zhu, YD1
Zhang, QF1
Xiang, HY1
Qi, J1
Feng, LL1
Zhu, P1
Hao, JH1
Tao, XG1
Tao, FB1
Vetrano, AM1
Archer, FE1
Marcella, SW1
Buckley, B1
Wartenberg, D1
Robson, MG1
Klim, J1
Azhar, S1
Cavin, S1
Wang, L2
Moreno, M1
Huang, Y1
Li, J1
Garcia, JM1
Lin, H1
Wang, Y1
Yan, P1
Tan, Y1
Luo, J1
Qiu, Z1
Chen, JA1
Shu, W1
Ko, YA1
Chen, YH1
VanderWeele, TJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Developmental Impact of Neonatal Intensive Care Unit (NICU) Exposures: Environmental Influences on Child Health Outcomes (ECHO)[NCT03061890]600 participants (Actual)Observational [Patient Registry]2017-04-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for phthalic acid and Preterm Birth

ArticleYear
Update about the disrupting-effects of phthalates on the human reproductive system.
    Molecular reproduction and development, 2021, Volume: 88, Issue:10

    Topics: Adult; Environmental Pollutants; Female; Genitalia; Humans; Infant, Newborn; Male; Phthalic Acids; P

2021
Phthalate Exposures and Placental Health in Animal Models and Humans: A Systematic Review.
    Toxicological sciences : an official journal of the Society of Toxicology, 2022, 07-28, Volume: 188, Issue:2

    Topics: Animals; Child; Female; Humans; Infant, Newborn; Models, Animal; Phthalic Acids; Placenta; Pregnancy

2022
Association between exposures to phthalate metabolites and preterm birth and spontaneous preterm birth: A systematic review and meta-analysis.
    Reproductive toxicology (Elmsford, N.Y.), 2022, Volume: 113

    Topics: Environmental Exposure; Environmental Pollutants; Female; Humans; Infant, Newborn; Phthalic Acids; P

2022
The Endocrine Disruption of Prenatal Phthalate Exposure in Mother and Offspring.
    Frontiers in public health, 2020, Volume: 8

    Topics: Adolescent; Child; Female; Humans; Infant; Infant, Newborn; Male; Mothers; Phthalic Acids; Pregnancy

2020
Prenatal exposure to phthalates with preterm birth and gestational age: A systematic review and meta-analysis.
    Chemosphere, 2021, Volume: 282

    Topics: Cohort Studies; Female; Gestational Age; Humans; Infant, Newborn; Multicenter Studies as Topic; Phth

2021

Other Studies

23 other studies available for phthalic acid and Preterm Birth

ArticleYear
Phthalate and DINCH urinary concentrations across pregnancy and risk of preterm birth.
    Environmental pollution (Barking, Essex : 1987), 2022, Jan-01, Volume: 292, Issue:Pt B

    Topics: Female; Humans; Infant, Newborn; Infertility; Phthalic Acids; Pregnancy; Premature Birth; Prospectiv

2022
Mediation by hormone concentrations on the associations between repeated measures of phthalate mixture exposure and timing of delivery.
    Journal of exposure science & environmental epidemiology, 2022, Volume: 32, Issue:3

    Topics: Environmental Pollutants; Female; Gestational Age; Hormones; Humans; Infant, Newborn; Male; Phthalic

2022
Biomarkers of Exposure to Phthalate Mixtures and Adverse Birth Outcomes in a Puerto Rico Birth Cohort.
    Environmental health perspectives, 2022, Volume: 130, Issue:3

    Topics: Bayes Theorem; Biomarkers; Birth Cohort; Birth Weight; Environmental Pollutants; Female; Humans; Inf

2022
Associations Between Prenatal Urinary Biomarkers of Phthalate Exposure and Preterm Birth: A Pooled Study of 16 US Cohorts.
    JAMA pediatrics, 2022, 09-01, Volume: 176, Issue:9

    Topics: Adult; Biomarkers; Female; Humans; Infant, Newborn; Maternal Exposure; Odds Ratio; Phthalic Acids; P

2022
Association between trimester-specific exposure to thirteen endocrine disrupting chemicals and preterm birth: Comparison of three statistical models.
    The Science of the total environment, 2022, Dec-10, Volume: 851, Issue:Pt 2

    Topics: Bayes Theorem; Benzothiazoles; Endocrine Disruptors; Environmental Pollutants; Female; Humans; Infan

2022
The safety of phthalate-containing medications used during pregnancy.
    Expert opinion on drug safety, 2023, Volume: 22, Issue:4

    Topics: Abortion, Spontaneous; Diabetes, Gestational; Female; Humans; Infant, Newborn; Maternal Exposure; Pl

2023
Associations of phthalates, phthalate replacements, and their mixtures with eicosanoid biomarkers during pregnancy.
    Environment international, 2023, Volume: 178

    Topics: Biomarkers; Environmental Exposure; Environmental Pollutants; Female; Humans; Hydroxyeicosatetraenoi

2023
Phthalate exposure in the neonatal intensive care unit is associated with development of bronchopulmonary dysplasia.
    Environment international, 2023, Volume: 178

    Topics: Bronchopulmonary Dysplasia; Child; Cohort Studies; Female; Gestational Age; Humans; Infant; Infant,

2023
The widely disregarded health risks posed by phthalates - A global call for action.
    Toxicology in vitro : an international journal published in association with BIBRA, 2023, Volume: 93

    Topics: Animals; Female; Humans; Infant, Newborn; Phthalic Acids; Plastics; Premature Birth; Reproduction

2023
Phthalate exposure from drugs during pregnancy and possible risk of preterm birth and small for gestational age.
    European journal of obstetrics, gynecology, and reproductive biology, 2019, Volume: 240

    Topics: Adult; Case-Control Studies; Denmark; Endocrine Disruptors; Environmental Exposure; Female; Humans;

2019
Joint impact of phthalate exposure and stressful life events in pregnancy on preterm birth.
    Environment international, 2019, Volume: 133, Issue:Pt B

    Topics: Adult; Female; Humans; Infant, Newborn; Male; Maternal Exposure; Phthalic Acids; Pregnancy; Pregnanc

2019
Is the Environment Associated With Preterm Birth?
    JAMA network open, 2020, 04-01, Volume: 3, Issue:4

    Topics: Female; Humans; Infant, Newborn; Parents; Phthalic Acids; Pregnancy; Premature Birth

2020
Associations of prenatal urinary phthalate exposure with preterm birth: the Maternal-Infant Research on Environmental Chemicals (MIREC) Study.
    Canadian journal of public health = Revue canadienne de sante publique, 2020, Volume: 111, Issue:3

    Topics: Adult; Canada; Cohort Studies; Female; Humans; Infant, Newborn; Male; Phthalic Acids; Pregnancy; Pre

2020
Maternal phthalate urine concentrations, fetal growth and adverse birth outcomes. A population-based prospective cohort study.
    Environment international, 2021, Volume: 151

    Topics: Cohort Studies; Female; Fetal Development; Humans; Infant, Newborn; Maternal Exposure; Netherlands;

2021
Parental preconception exposure to phenol and phthalate mixtures and the risk of preterm birth.
    Environment international, 2021, Volume: 151

    Topics: Bayes Theorem; Benzhydryl Compounds; Diethylhexyl Phthalate; Female; Humans; Infant; Infant, Newborn

2021
Prenatal phthalate exposure in relation to gestational age and preterm birth in a prospective cohort study.
    Environmental research, 2019, Volume: 176

    Topics: Female; Gestational Age; Humans; Infant, Newborn; Maternal Exposure; Phthalic Acids; Pregnancy; Preg

2019
Effects of maternal exposure to phthalates and bisphenol A during pregnancy on gestational age.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2014, Volume: 27, Issue:4

    Topics: Adolescent; Adult; Benzhydryl Compounds; Biomarkers; Environmental Pollutants; Female; Gestational A

2014
Environmental phthalate exposure and the odds of preterm birth: an important contribution to environmental reproductive epidemiology.
    JAMA pediatrics, 2014, Volume: 168, Issue:1

    Topics: Environmental Exposure; Female; Humans; Maternal Exposure; Phthalic Acids; Pregnancy; Premature Birt

2014
Environmental phthalate exposure and preterm birth.
    JAMA pediatrics, 2014, Volume: 168, Issue:1

    Topics: Adult; Case-Control Studies; Environmental Exposure; Female; Humans; Infant, Newborn; Massachusetts;

2014
JAMA Pediatrics patient page. Phthalate exposure and health risks.
    JAMA pediatrics, 2014, Volume: 168, Issue:1

    Topics: Environmental Exposure; Female; Humans; Infant, Newborn; Phthalic Acids; Pregnancy; Premature Birth;

2014
Phthalate levels in cord blood are associated with preterm delivery and fetal growth parameters in Chinese women.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Asian People; Birth Weight; China; Esters; Female; Fetal Blood; Fetal Development; Gestational Age;

2014
Variability in urinary phthalate metabolite levels across pregnancy and sensitive windows of exposure for the risk of preterm birth.
    Environment international, 2014, Volume: 70

    Topics: Adult; Boston; Diethylhexyl Phthalate; Female; Humans; Infant, Newborn; Male; Maternal Exposure; Pht

2014
Mediation of the Relationship between Maternal Phthalate Exposure and Preterm Birth by Oxidative Stress with Repeated Measurements across Pregnancy.
    Environmental health perspectives, 2017, Volume: 125, Issue:3

    Topics: Biomarkers; Environmental Pollutants; Female; Humans; Maternal Exposure; Oxidative Stress; Phthalic

2017