phthalic acid has been researched along with Insulin Resistance in 14 studies
phthalic acid: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7178
phthalic acid : A benzenedicarboxylic acid cosisting of two carboxy groups at ortho positions.
Insulin Resistance: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Insulin resistance was assessed using homeostatic model assessment (HOMA) and defined as HOMA-IR >2." | 5.72 | Mixed exposure to phenol, parabens, pesticides, and phthalates and insulin resistance in NHANES: A mixture approach. ( Bai, J; Ma, Y; Mubarik, S; Yang, D; Yu, C; Zhao, Y, 2022) |
| " We modeled six phthalate metabolites with prevalent exposure and known or suspected antiandrogenic activity as predictors of waist circumference and log-transformed homeostatic model assessment (HOMA; a measure of insulin resistance) using multiple linear regression, adjusted for age, race/ethnicity, fat and total calorie consumption, physical activity level, serum cotinine, and urine creatinine (model 1); and adjusted for model 1 covariates plus measures of renal and hepatic function (model 2)." | 3.74 | Concentrations of urinary phthalate metabolites are associated with increased waist circumference and insulin resistance in adult U.S. males. ( Cook, S; Dye, TD; Stahlhut, RW; Swan, SH; van Wijngaarden, E, 2007) |
| "Insulin resistance was assessed using homeostatic model assessment (HOMA) and defined as HOMA-IR >2." | 1.72 | Mixed exposure to phenol, parabens, pesticides, and phthalates and insulin resistance in NHANES: A mixture approach. ( Bai, J; Ma, Y; Mubarik, S; Yang, D; Yu, C; Zhao, Y, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 6 (42.86) | 24.3611 |
| 2020's | 7 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gao, H | 1 |
| Chen, D | 1 |
| Zang, M | 1 |
| Zhang, W | 1 |
| Xu, P | 1 |
| Li, JY | 1 |
| Hsia, TI | 1 |
| Huang, PC | 2 |
| Chen, HC | 1 |
| Lo, YC | 2 |
| Chang, WT | 1 |
| Jou, YY | 1 |
| Huang, HB | 2 |
| Wei, X | 1 |
| Yang, D | 2 |
| Zhang, B | 1 |
| Fan, X | 1 |
| Du, H | 1 |
| Zhu, R | 1 |
| Sun, X | 1 |
| Zhao, M | 1 |
| Gu, N | 1 |
| Bai, J | 1 |
| Ma, Y | 1 |
| Zhao, Y | 1 |
| Mubarik, S | 1 |
| Yu, C | 1 |
| Etzel, TM | 2 |
| Kuiper, JR | 2 |
| Wang, X | 2 |
| Mueller, NT | 2 |
| Calafat, AM | 2 |
| Cecil, KM | 2 |
| Chen, A | 2 |
| Lanphear, BP | 2 |
| Yolton, K | 2 |
| Kalkwarf, HJ | 2 |
| Braun, JM | 2 |
| Buckley, JP | 2 |
| Milankov, A | 1 |
| Milanović, M | 1 |
| Milošević, N | 1 |
| Sudji, J | 1 |
| Pejaković, S | 1 |
| Milić, N | 1 |
| Bjelica, A | 1 |
| Medić Stojanoska, M | 1 |
| Li, MC | 1 |
| Mínguez-Alarcón, L | 1 |
| Bellavia, A | 1 |
| Williams, PL | 1 |
| James-Todd, T | 1 |
| Hauser, R | 1 |
| Chavarro, JE | 1 |
| Chiu, YH | 1 |
| Lee, I | 1 |
| Kim, S | 2 |
| Park, S | 1 |
| Mok, S | 1 |
| Jeong, Y | 1 |
| Moon, HB | 1 |
| Lee, J | 1 |
| Kim, HJ | 1 |
| Choi, G | 1 |
| Choi, S | 1 |
| Kim, SY | 1 |
| Lee, A | 1 |
| Park, J | 1 |
| Choi, K | 1 |
| Chen, SY | 1 |
| Hwang, JS | 1 |
| Sung, FC | 1 |
| Lin, CY | 1 |
| Hsieh, CJ | 1 |
| Chen, PC | 1 |
| Su, TC | 1 |
| Dong, R | 1 |
| Chen, J | 1 |
| Zheng, J | 1 |
| Zhang, M | 1 |
| Zhang, H | 1 |
| Wu, M | 1 |
| Li, S | 1 |
| Chen, B | 1 |
| Shoshtari-Yeganeh, B | 1 |
| Zarean, M | 1 |
| Mansourian, M | 1 |
| Riahi, R | 1 |
| Poursafa, P | 1 |
| Teiri, H | 1 |
| Rafiei, N | 1 |
| Dehdashti, B | 1 |
| Kelishadi, R | 1 |
| Ko, NY | 1 |
| Huang, YC | 1 |
| Chang, JL | 1 |
| Stahlhut, RW | 1 |
| van Wijngaarden, E | 1 |
| Dye, TD | 1 |
| Cook, S | 1 |
| Swan, SH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Associations of Exposure to Phthalates With Insulin Resistance and Epigenetic Change[NCT02284477] | 60 participants (Anticipated) | Interventional | 2015-01-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for phthalic acid and Insulin Resistance
| Article | Year |
|---|---|
Association between phthalate exposure and insulin resistance: a systematic review and meta-analysis update.
Topics: Adolescent; Adult; Asia; Environmental Exposure; Environmental Pollutants; Female; Humans; Insulin; | 2021 |
Systematic review and meta-analysis on the association between phthalates exposure and insulin resistance.
Topics: Diabetes Mellitus; Environmental Exposure; Environmental Pollutants; Esters; Europe; Humans; Insulin | 2019 |
12 other studies available for phthalic acid and Insulin Resistance
| Article | Year |
|---|---|
The crucial role of thioredoxin interacting protein in the liver insulin resistance induced by di (2-ethylhexyl) phthalates.
Topics: Diethylhexyl Phthalate; Humans; Insulin; Insulin Resistance; Liver; Phosphatidylinositol 3-Kinases; | 2022 |
Relationships among phthalate exposure, oxidative stress, and insulin resistance in young military soldiers: A cumulative risk assessment and mediation approach.
Topics: Biomarkers; Dibutyl Phthalate; Diethylhexyl Phthalate; Environmental Exposure; Environmental Polluta | 2022 |
Di-(2-ethylhexyl) phthalate increases plasma glucose and induces lipid metabolic disorders via FoxO1 in adult mice.
Topics: Animals; Blood Glucose; Diethylhexyl Phthalate; Forkhead Box Protein O1; Glucose; Insulin Resistance | 2022 |
Mixed exposure to phenol, parabens, pesticides, and phthalates and insulin resistance in NHANES: A mixture approach.
Topics: Bayes Theorem; Chlorophenols; Diethylhexyl Phthalate; Environmental Exposure; Environmental Pollutan | 2022 |
Associations of early life phthalate exposures with adolescent lipid levels and insulin resistance: The HOME Study.
Topics: Adolescent; Biomarkers; Cardiovascular Diseases; Child; Environmental Exposure; Environmental Pollut | 2023 |
Associations of early life phthalate exposures with adolescent lipid levels and insulin resistance: The HOME Study.
Topics: Adolescent; Biomarkers; Cardiovascular Diseases; Child; Environmental Exposure; Environmental Pollut | 2023 |
Associations of early life phthalate exposures with adolescent lipid levels and insulin resistance: The HOME Study.
Topics: Adolescent; Biomarkers; Cardiovascular Diseases; Child; Environmental Exposure; Environmental Pollut | 2023 |
Associations of early life phthalate exposures with adolescent lipid levels and insulin resistance: The HOME Study.
Topics: Adolescent; Biomarkers; Cardiovascular Diseases; Child; Environmental Exposure; Environmental Pollut | 2023 |
The effects of phthalate exposure on metabolic parameters in polycystic ovary syndrome.
Topics: Blood Glucose; Body Mass Index; Cholesterol, HDL; Cross-Sectional Studies; Female; Humans; Insulin; | 2023 |
Serum beta-carotene modifies the association between phthalate mixtures and insulin resistance: The National Health and Nutrition Examination Survey 2003-2006.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bayes Theorem; beta Carotene; Child; Cross-Sectional Stu | 2019 |
Association of urinary phthalate metabolites and phenolics with adipokines and insulin resistance related markers among women of reproductive age.
Topics: Adult; Biomarkers; Environmental Exposure; Environmental Pollutants; Female; Humans; Insulin Resista | 2019 |
Mono-2-ethylhexyl phthalate associated with insulin resistance and lower testosterone levels in a young population.
Topics: Adolescent; Adult; Child; Diethylhexyl Phthalate; Environmental Exposure; Environmental Pollutants; | 2017 |
The role of oxidative stress in cardiometabolic risk related to phthalate exposure in elderly diabetic patients from Shanghai.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Biomarkers; China; Deoxyguanosine; Diabetes Mellitus; Diabetic Ca | 2018 |
Changes in insulin resistance mediate the associations between phthalate exposure and metabolic syndrome.
Topics: Adult; Cross-Sectional Studies; Environmental Exposure; Environmental Pollutants; Humans; Insulin Re | 2019 |
Concentrations of urinary phthalate metabolites are associated with increased waist circumference and insulin resistance in adult U.S. males.
Topics: Adult; Age Factors; Biomarkers; Body Weights and Measures; Cotinine; Creatinine; Diet; Environmental | 2007 |