Page last updated: 2024-10-20

phthalic acid and Innate Inflammatory Response

phthalic acid has been researched along with Innate Inflammatory Response in 29 studies

phthalic acid: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7178
phthalic acid : A benzenedicarboxylic acid cosisting of two carboxy groups at ortho positions.

Research Excerpts

ExcerptRelevanceReference
"Lycopene is a natural bioactive component that can potentially reduce the risk of environmental factor-induced chronic diseases."5.91Lycopene Attenuates Di(2-ethylhexyl) Phthalate-Induced Mitochondrial Damage and Inflammation in Kidney via cGAS-STING Signaling. ( Dai, XY; Li, JL; Li, MZ; Li, XW; Zhao, Y; Zhao, YX, 2023)
"Lycopene is a natural bioactive component that can potentially reduce the risk of environmental factor-induced chronic diseases."1.91Lycopene Attenuates Di(2-ethylhexyl) Phthalate-Induced Mitochondrial Damage and Inflammation in Kidney via cGAS-STING Signaling. ( Dai, XY; Li, JL; Li, MZ; Li, XW; Zhao, Y; Zhao, YX, 2023)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (3.45)29.6817
2010's13 (44.83)24.3611
2020's15 (51.72)2.80

Authors

AuthorsStudies
Saunders, MJ1
Edwards, BS1
Zhu, J1
Sklar, LA1
Graves, SW1
Schaffert, A1
Arnold, J1
Karkossa, I1
Blüher, M1
von Bergen, M1
Schubert, K1
Bao, C1
Lv, J1
Chen, JR1
Wei, GZ1
Liu, N2
Wang, YT1
Ding, Z1
Liu, WB1
Li, XD1
Cao, HJ1
Sheng, J2
Liu, KY1
He, J1
Tao, FB2
Wang, QN2
Schwendt, A1
Chammas, JB1
Chalifour, LE1
Zhou, X1
Zhang, Z1
Shi, H1
Liu, Q1
Chang, Y1
Feng, W1
Zhu, S1
Sun, S1
Fandiño-Del-Rio, M1
Matsui, EC1
Peng, RD1
Meeker, JD4
Quirós-Alcalá, L1
Hou, P1
Dai, W1
Jin, Y1
Zhao, F1
Liu, J1
Liu, H1
Wang, JQ1
Liang, CM1
Hu, YB1
Xia, X1
Li, ZJ1
Gao, H1
Huang, K1
Wang, SF1
Zhu, P1
Hao, JH1
Lai, CC1
Liu, FL1
Tsai, CY1
Wang, SL1
Chang, DM1
Li, MZ1
Dai, XY1
Zhao, YX1
Li, XW1
Zhao, Y1
Li, JL1
Zhang, Y1
Qian, H1
Wang, J1
Zhu, Y1
Miao, X1
Li, X1
Yin, J1
Zhang, R1
Ye, J1
Huo, C1
Zhao, W1
Ye, L1
Kim, SH1
Quoc, QL1
Park, HS1
Shin, YS1
Qian, Y1
Zhu, L1
Chen, J1
Zhou, Y1
Huang, Z1
Liang, L1
Ding, B1
Ren, WQ1
Shen, Y1
Wang, XY1
Zhou, Q1
Rui, C1
Yang, XH1
Cao, SL1
Li, LY1
Wāng, Y1
Yang, L1
Yin, W1
Li, P1
Hu, C1
Hou, J1
Wang, L1
Yuan, J1
Yu, Z1
Trim, A1
Hankinson, SE1
Liu, S1
Shadyab, AH1
Meliker, J1
Bao, W1
Luo, J1
Liu, B1
Manson, JE1
Tinker, L1
Bigelow, C1
Reeves, KW1
Vercelli, D1
Mazioti, M1
Bahrami, N1
Mehrzadi, S1
Goudarzi, M1
Mansouri, E1
Fatemi, I1
Svoboda, E1
Kelley, AS1
Banker, M1
Goodrich, JM1
Dolinoy, DC1
Burant, C1
Domino, SE1
Smith, YR1
Song, PXK1
Padmanabhan, V1
Sweeney, MR1
O'Leary, KG1
Jeney, Z1
Braunlin, MC1
Gibb, HJ1
Ferguson, KK3
Cantonwine, DE1
Rivera-González, LO1
Loch-Caruso, R3
Mukherjee, B2
Anzalota Del Toro, LV1
Jiménez-Vélez, B1
Calafat, AM1
Ye, X1
Alshawabkeh, AN1
Cordero, JF1
McElrath, TF1
Bornehag, CG1
Nanberg, E1
Vetrano, AM1
Laskin, DL1
Archer, F1
Syed, K1
Gray, JP1
Laskin, JD1
Nwebube, N1
Weinberger, B1
Singh, S1
Li, SS1
Latini, G1
Massaro, M1
De Felice, C1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Personalized Mobile Intervention to Reduce Exposure to Endocrine Disrupting Chemicals (EDCs) in Women of Child-Bearing Age and Their Partners[NCT05780047]220 participants (Actual)Interventional2022-05-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for phthalic acid and Innate Inflammatory Response

ArticleYear
Systematic review and quality ranking of studies of two phthalate metabolites and anogenital distance, bone health, inflammation, and oxidative stress.
    Critical reviews in toxicology, 2019, Volume: 49, Issue:4

    Topics: Adult; Anal Canal; Bone Density; Environmental Exposure; Environmental Pollutants; Female; Genitalia

2019
Phthalate exposure and asthma in children.
    International journal of andrology, 2010, Volume: 33, Issue:2

    Topics: Adolescent; Animals; Asthma; Child; Diethylhexyl Phthalate; Endocrine Disruptors; Environmental Expo

2010

Other Studies

27 other studies available for phthalic acid and Innate Inflammatory Response

ArticleYear
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr

2010
The Emerging Plasticizer Alternative DINCH and Its Metabolite MINCH Induce Oxidative Stress and Enhance Inflammatory Responses in Human THP-1 Macrophages.
    Cells, 2021, 09-09, Volume: 10, Issue:9

    Topics: Apoptosis; Dicarboxylic Acids; DNA Damage; DNA Repair; Esters; Humans; Inflammation; Macrophages; NF

2021
Chronic inflammation as a potential mediator between phthalate exposure and depressive symptoms.
    Ecotoxicology and environmental safety, 2022, Mar-15, Volume: 233

    Topics: Aged; Depression; Dibutyl Phthalate; Environmental Exposure; Environmental Pollutants; Humans; Infla

2022
Acute exposure to phthalates during recovery from a myocardial infarction induces greater inflammasome activation in male C57bl/6N mice.
    Toxicology and applied pharmacology, 2022, 04-01, Volume: 440

    Topics: Animals; Humans; Inflammasomes; Inflammation; Male; Mice; Mice, Inbred C57BL; Myocardial Infarction;

2022
Effects of Lycium barbarum glycopeptide on renal and testicular injury induced by di(2-ethylhexyl) phthalate.
    Cell stress & chaperones, 2022, Volume: 27, Issue:3

    Topics: Diethylhexyl Phthalate; Glycopeptides; HEK293 Cells; Humans; Inflammation; Kidney; Lycium; Male; Pht

2022
Phthalate biomarkers and associations with respiratory symptoms and healthcare utilization among low-income urban children with asthma.
    Environmental research, 2022, Volume: 212, Issue:Pt B

    Topics: Asthma; Biomarkers; Child; Delivery of Health Care; Diethylhexyl Phthalate; Environmental Exposure;

2022
Maternal exposure to di-2-ethylhexyl phthalate (DEHP) depresses lactation capacity in mice.
    The Science of the total environment, 2022, Sep-01, Volume: 837

    Topics: Animals; Diethylhexyl Phthalate; Female; Humans; Inflammation; Insulin; Lactation; Maternal Exposure

2022
The effect of phthalates exposure during pregnancy on asthma in infants aged 0 to 36 months: a birth cohort study.
    Environmental geochemistry and health, 2023, Volume: 45, Issue:5

    Topics: Asthma; Child; Child, Preschool; Cohort Studies; Environmental Exposure; Environmental Pollutants; F

2023
Di-(2-ethylhexyl) phthalate exposure links to inflammation and low bone mass in premenopausal and postmenopausal females: Evidence from ovariectomized mice and humans.
    International journal of rheumatic diseases, 2022, Volume: 25, Issue:8

    Topics: Animals; Bone Density; Diethylhexyl Phthalate; Female; Humans; Inflammation; Interleukin-10; Interle

2022
Lycopene Attenuates Di(2-ethylhexyl) Phthalate-Induced Mitochondrial Damage and Inflammation in Kidney via cGAS-STING Signaling.
    Journal of agricultural and food chemistry, 2023, Jan-11, Volume: 71, Issue:1

    Topics: Animals; Diethylhexyl Phthalate; DNA, Mitochondrial; Inflammation; Interferons; Kidney; Lycopene; Mi

2023
Di-(2-ethylhexyl) phthalate (DEHP) promoted hepatic lipid accumulation by activating Notch signaling pathway.
    Environmental toxicology, 2023, Volume: 38, Issue:7

    Topics: Animals; Diethylhexyl Phthalate; Inflammation; Lipids; Liver; Male; Rats; Rats, Wistar; Signal Trans

2023
The effect of apigenin, an aryl hydrocarbon receptor antagonist, in Phthalate-Exacerbated eosinophilic asthma model.
    Journal of cellular and molecular medicine, 2023, Volume: 27, Issue:13

    Topics: Animals; Apigenin; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Inflamma

2023
Di-(2-ethylhexyl) phthalate aggravates psoriasis-like skin lesions: In vitro and in vivo evaluation.
    Toxicology and applied pharmacology, 2023, Nov-15, Volume: 479

    Topics: Animals; Diethylhexyl Phthalate; Humans; Imiquimod; Inflammation; Mice; p38 Mitogen-Activated Protei

2023
Subchronic exposure to di-(2-ethylhexyl) phthalate (DEHP) elicits blood-brain barrier dysfunction and neuroinflammation in male C57BL/6J mice.
    Toxicology, 2023, Volume: 499

    Topics: Animals; Blood-Brain Barrier; Diethylhexyl Phthalate; Inflammation; Male; Mice; Mice, Inbred C57BL;

2023
Seasonal exposure to phthalates and inflammatory parameters: A pilot study with repeated measures.
    Ecotoxicology and environmental safety, 2021, Jan-15, Volume: 208

    Topics: China; Environmental Exposure; Environmental Pollutants; Female; Humans; Inflammation; Male; Phthali

2021
Biomarkers of phthalates and inflammation: Findings from a subgroup of Women's Health Initiative participants.
    International journal of hygiene and environmental health, 2021, Volume: 234

    Topics: Biomarkers; Case-Control Studies; Environmental Exposure; Environmental Pollutants; Female; Humans;

2021
Are we what our mothers made us? Lessons from epigenetics.
    The Journal of allergy and clinical immunology, 2018, Volume: 141, Issue:2

    Topics: Epigenesis, Genetic; Epigenomics; Female; Humans; Inflammation; Mothers; Phthalic Acids

2018
The potential role of endocrine disrupting chemicals in cellulite.
    Medical hypotheses, 2018, Volume: 116

    Topics: Benzhydryl Compounds; Cellulite; Endocrine Disruptors; Environmental Exposure; Estrogens; Homeostasi

2018
Lycopene abrogates di-(2-ethylhexyl) phthalate induced testicular injury by modulating oxidative, endocrine and inflammatory changes in mice.
    Life sciences, 2018, Aug-15, Volume: 207

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Carotenoids; Diethylhexyl Phthalate; Endocrine Syst

2018
When skin's defence against pollution fails.
    Nature, 2018, Volume: 563, Issue:7732

    Topics: Benzhydryl Compounds; Chlorpyrifos; Eczema; Environmental Pollution; Female; Humans; Inflammation; M

2018
Early pregnancy exposure to endocrine disrupting chemical mixtures are associated with inflammatory changes in maternal and neonatal circulation.
    Scientific reports, 2019, 04-01, Volume: 9, Issue:1

    Topics: Adolescent; Adult; Birth Weight; Cytokines; Endocrine Disruptors; Female; Gestational Age; Humans; I

2019
Urinary phthalate metabolite associations with biomarkers of inflammation and oxidative stress across pregnancy in Puerto Rico.
    Environmental science & technology, 2014, Jun-17, Volume: 48, Issue:12

    Topics: Adult; Biomarkers; Confidence Intervals; Female; Humans; Inflammation; Linear Models; Oxidative Stre

2014
Associations between Maternal Biomarkers of Phthalate Exposure and Inflammation Using Repeated Measurements across Pregnancy.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: Adult; Biomarkers; Case-Control Studies; Female; Humans; Infant, Newborn; Inflammation; Inflammation

2015
Inflammatory effects of phthalates in neonatal neutrophils.
    Pediatric research, 2010, Volume: 68, Issue:2

    Topics: Adult; Apoptosis; Chemotaxis; Diethylhexyl Phthalate; Humans; Hydrogen Peroxide; Infant, Newborn; In

2010
Exploration of oxidative stress and inflammatory markers in relation to urinary phthalate metabolites: NHANES 1999-2006.
    Environmental science & technology, 2012, Jan-03, Volume: 46, Issue:1

    Topics: Adolescent; Adult; Biomarkers; Child; Female; Humans; Inflammation; Male; Middle Aged; Multivariate

2012
Bisphenol A and phthalates exhibit similar toxicogenomics and health effects.
    Gene, 2012, Feb-15, Volume: 494, Issue:1

    Topics: Benzhydryl Compounds; Databases as Topic; Environmental Exposure; Humans; Inflammation; Phenols; Pht

2012
Prenatal exposure to phthalates and intrauterine inflammation: a unifying hypothesis.
    Toxicological sciences : an official journal of the Society of Toxicology, 2005, Volume: 85, Issue:1

    Topics: Animals; Female; Fetal Development; Inflammation; Phthalic Acids; Pregnancy; Prenatal Exposure Delay

2005